ketoconazole has been researched along with Adenocarcinoma, Basal Cell in 49 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole has been used with success to treat disseminated intravascular coagulation and acute spinal cord compression syndromes associated with metastatic prostatic adenocarcinoma." | 8.79 | Ketoconazole-induced adrenal crisis in a patient with metastatic prostatic adenocarcinoma: case report and review of the literature. ( Ahmann, FR; Dalkin, BL; Sarver, RG, 1997) |
| "We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma." | 7.67 | Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989) |
| "• Ketoconazole was administered by oral route at a dose of 200 mg every 8 h continuous dosing until the onset of serious adverse events or disease progression." | 6.76 | Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration. ( Bajetta, E; Capone, F; Giganti, MO; Guadalupi, V; Mariani, L; Nicolai, N; Procopio, G; Salvioni, R; Valdagni, R, 2011) |
| "Biological investigations revealed a disseminated intravascular coagulation (DIC)." | 6.38 | [Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative]. ( Balin, C; Fleyfel, M; Leroy, B; Marecaux, O; Plouvier, F; Scherpereel, P, 1991) |
| "A patient with spontaneous bleeding from disseminated intravascular coagulation was treated with 400 mg." | 5.27 | The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer. ( Lowe, FC; Somers, WJ, 1987) |
| "Ketoconazole has been used with success to treat disseminated intravascular coagulation and acute spinal cord compression syndromes associated with metastatic prostatic adenocarcinoma." | 4.79 | Ketoconazole-induced adrenal crisis in a patient with metastatic prostatic adenocarcinoma: case report and review of the literature. ( Ahmann, FR; Dalkin, BL; Sarver, RG, 1997) |
| "These results indicate that ketoconazole significantly reduced hepatic metastases from the human pancreatic carcinoma RWP-2 in the nude mouse model, and inhibited thromboxane B2 formation, potentiating a concomitant redirection of platelet endoperoxide metabolism into PGD2, PGE2, and 6-keto-F1a." | 3.71 | The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. ( Krambovitis, E; Tsatsakis, AM; Tzanakakis, GN; Vezeridis, MP, 2002) |
| "The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachidonic acid lipoxygenases and cytochrome P-450 enzymes, were tested in human colon and breast cancer cell lines." | 3.68 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. ( Coudray, AM; Fagot, D; Forgue-Lafitte, ME; Mester, J, 1992) |
| "We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma." | 3.67 | Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989) |
| "• Ketoconazole was administered by oral route at a dose of 200 mg every 8 h continuous dosing until the onset of serious adverse events or disease progression." | 2.76 | Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration. ( Bajetta, E; Capone, F; Giganti, MO; Guadalupi, V; Mariani, L; Nicolai, N; Procopio, G; Salvioni, R; Valdagni, R, 2011) |
| " Overall, the chemotherapy combined with Sr-89 was well tolerated." | 2.73 | Bone-targeted therapy: phase II study of strontium-89 in combination with alternating weekly chemohormonal therapies for patients with advanced androgen-independent prostate cancer. ( Amato, RJ; Henary, H; Hernandez-McClain, J, 2008) |
| "The role of inhibition of aromatase in prostate cancer therapy, which was postulated for aminoglutethimide, could not be confirmed by the use of more selective aromatase inhibitors, such as formestane." | 2.39 | P450-dependent enzymes as targets for prostate cancer therapy. ( Bruynseels, J; De Coster, R; Wouters, W, 1996) |
| "Biological investigations revealed a disseminated intravascular coagulation (DIC)." | 2.38 | [Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative]. ( Balin, C; Fleyfel, M; Leroy, B; Marecaux, O; Plouvier, F; Scherpereel, P, 1991) |
| "Radiation port dermatophytosis is the occurrence of tinea corporis within the area of radiation therapy delivery." | 1.38 | Radiation port dermatophytosis: tinea corporis occurring at the site of irradiated skin. ( Casamiquela, KM; Cohen, PR, 2012) |
| "Unfortunately the patient died of respiratory failure due to metastasis." | 1.37 | [Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma]. ( Montes-Mollón, MÁ; Paz Moreno-Arrones, J, 2011) |
| "We report the case of a patient with prostate cancer who develops mediastinal lymphadenopathy, pulmonary nodules and cutaneous metastases 8 years after the diagnosis." | 1.34 | [Mediastinal lymph nodes during the course of a metastatic prostate cancer]. ( Aguilera Tubet, C; Ballestero Diego, R; Roca Edreira, A; Villanueva Peña, A; Zubillaga Guerrero, S, 2007) |
| "Ketoconazole was generally well tolerated." | 1.34 | Efficacy of low-dose ketoconazole in hormone refractory prostate cancer patients at the National Cancer Centre and The Cancer Institute, Singapore. ( Ngo, LS; Tay, MH; Wong, AS; Yeo, A, 2007) |
| "at bedtime)." | 1.31 | Low dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen independent prostate cancer. ( Bok, RA; Harris, KA; Kakefuda, M; Small, EJ; Weinberg, V, 2002) |
| "In patients with metastatic prostate cancer, we are evaluating the addition of the bisphosphonate alendronate when added to ketoconazole for impact on matrix metalloproteinase (MMP)-2 and MMP-9 as well as traditional clinical endpoints." | 1.31 | National Cancer Institute intramural approach to advanced prostate cancer. ( Arlen, PM; Cox, MC; Dahut, W; Figg, WD; Gulley, J; Linehan, WM, 2002) |
| "Cushing's syndrome is infrequently associated with adenocarcinomas of the lung." | 1.30 | [Paraneoplastic hypercorticism associated with a bronchial adenocarcinoma]. ( Chaouat, A; Kessler, R; Schott, R; Tavernier, M; Weitzenblum, E, 1999) |
| "Metastases to the meninges from prostatic cancer are rare, accounting for less than 0." | 1.29 | Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma. ( DeAngelis, LM; Mencel, PJ; Motzer, RJ, 1994) |
| "A patient with invasive basophilic pituitary adenoma is described, in whom the hypercortisolaemia and clinical features persisted despite two attempts to reduce the tumour mass by transfrontal pituitary surgery and external beam radiotherapy." | 1.28 | Persistent Cushing's disease in a patient with invasive pituitary adenoma. ( Dash, RJ; Kak, VK; Khandekar, S, 1990) |
| "Ketoconazole is a potent inhibitor of the P450 series of enzymes that are essential for the production of androgens." | 1.27 | The effects of ketoconazole on testosterone production and normal and malignant androgen dependent tissues of the adult rat. ( Trachtenberg, J, 1984) |
| "Ketoconazole can suppress androgen production and has a beneficial role in the hormonal therapy of patients with prostate cancer who have not undergone orchiectomy." | 1.27 | High-dose ketoconazole therapy in patients with metastatic prostate cancer. ( Al-Sarraf, M; Decker, DA; Kresge, C; Subramanian, MG; Tapazoglou, E, 1986) |
| "A patient with spontaneous bleeding from disseminated intravascular coagulation was treated with 400 mg." | 1.27 | The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer. ( Lowe, FC; Somers, WJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.53) | 18.7374 |
| 1990's | 14 (28.57) | 18.2507 |
| 2000's | 13 (26.53) | 29.6817 |
| 2010's | 9 (18.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arun, Y | 1 |
| Bhaskar, G | 1 |
| Balachandran, C | 1 |
| Ignacimuthu, S | 1 |
| Perumal, PT | 1 |
| Jivrajani, M | 1 |
| Shaikh, MV | 1 |
| Shrivastava, N | 1 |
| Nivsarkar, M | 1 |
| Pokuri, VK | 1 |
| Nourkeyhani, H | 1 |
| Betsy, B | 1 |
| Herbst, L | 1 |
| Sikorski, M | 1 |
| Spangenthal, E | 1 |
| Fabiano, A | 1 |
| George, S | 1 |
| Amato, RJ | 1 |
| Hernandez-McClain, J | 1 |
| Henary, H | 1 |
| Procopio, G | 1 |
| Guadalupi, V | 1 |
| Giganti, MO | 1 |
| Mariani, L | 1 |
| Salvioni, R | 1 |
| Nicolai, N | 1 |
| Capone, F | 1 |
| Valdagni, R | 1 |
| Bajetta, E | 1 |
| Kota, BP | 1 |
| Allen, JD | 1 |
| Roufogalis, BD | 1 |
| Paz Moreno-Arrones, J | 1 |
| Montes-Mollón, MÁ | 1 |
| Lin, GW | 1 |
| Yao, XD | 1 |
| Ye, DW | 1 |
| Casamiquela, KM | 1 |
| Cohen, PR | 1 |
| Harris, KA | 1 |
| Weinberg, V | 1 |
| Bok, RA | 1 |
| Kakefuda, M | 1 |
| Small, EJ | 2 |
| Wang, YJ | 1 |
| Jeng, JH | 1 |
| Chen, RJ | 2 |
| Tseng, H | 1 |
| Chen, LC | 1 |
| Liang, YC | 1 |
| Lin, CH | 1 |
| Chen, CH | 1 |
| Chu, JS | 1 |
| Ho, WL | 1 |
| Ho, YS | 2 |
| Millikan, R | 1 |
| Thall, PF | 1 |
| Lee, SJ | 1 |
| Jones, D | 1 |
| Cannon, MW | 1 |
| Kuebler, JP | 1 |
| Wade, J | 1 |
| Logothetis, CJ | 1 |
| Tzanakakis, GN | 3 |
| Krambovitis, E | 1 |
| Tsatsakis, AM | 1 |
| Vezeridis, MP | 3 |
| Walczak, JR | 1 |
| Carducci, MA | 1 |
| Halabi, S | 1 |
| Dawson, NA | 1 |
| Stadler, WM | 1 |
| Rini, BI | 1 |
| Picus, J | 1 |
| Gable, P | 1 |
| Torti, FM | 2 |
| Kaplan, E | 1 |
| Vogelzang, NJ | 1 |
| Arlen, PM | 1 |
| Figg, WD | 1 |
| Gulley, J | 1 |
| Cox, MC | 1 |
| Linehan, WM | 1 |
| Dahut, W | 1 |
| Hobdy, EM | 1 |
| Shafi, NQ | 1 |
| Kummar, S | 1 |
| Roca Edreira, A | 1 |
| Aguilera Tubet, C | 1 |
| Villanueva Peña, A | 1 |
| Ballestero Diego, R | 1 |
| Zubillaga Guerrero, S | 1 |
| Ngo, LS | 1 |
| Yeo, A | 1 |
| Wong, AS | 1 |
| Tay, MH | 1 |
| Trachtenberg, J | 1 |
| Allen, JM | 1 |
| Kerle, DJ | 1 |
| Ware, H | 1 |
| Doble, A | 1 |
| Williams, G | 1 |
| Bloom, SR | 1 |
| Mencel, PJ | 1 |
| DeAngelis, LM | 1 |
| Motzer, RJ | 1 |
| De Coster, R | 1 |
| Wouters, W | 1 |
| Bruynseels, J | 1 |
| Sarver, RG | 1 |
| Dalkin, BL | 1 |
| Ahmann, FR | 1 |
| Vermuyten, K | 1 |
| Laurijssens, L | 1 |
| Vanden Bossche, H | 1 |
| Bare, RL | 1 |
| Tsai, PW | 1 |
| Yu, CF | 1 |
| Liu, HL | 1 |
| Lin, JK | 1 |
| Schott, R | 1 |
| Chaouat, A | 1 |
| Tavernier, M | 1 |
| Kessler, R | 1 |
| Weitzenblum, E | 1 |
| Rickman, T | 1 |
| Garmany, R | 1 |
| Doherty, T | 1 |
| Benson, D | 1 |
| Okusa, MD | 1 |
| Verlinden, L | 1 |
| Verstuyf, A | 1 |
| Quack, M | 1 |
| Van Camp, M | 1 |
| Van Etten, E | 1 |
| De Clercq, P | 1 |
| Vandewalle, M | 1 |
| Carlberg, C | 1 |
| Bouillon, R | 1 |
| Forgue-Lafitte, ME | 1 |
| Coudray, AM | 1 |
| Fagot, D | 1 |
| Mester, J | 1 |
| Gerber, GS | 1 |
| Chodak, GW | 1 |
| Agarwal, KC | 2 |
| Veronikis, DK | 1 |
| Fleyfel, M | 1 |
| Leroy, B | 1 |
| Plouvier, F | 1 |
| Balin, C | 1 |
| Marecaux, O | 1 |
| Scherpereel, P | 1 |
| Ahmad, S | 1 |
| Dash, RJ | 1 |
| Khandekar, S | 1 |
| Kak, VK | 1 |
| Bhadoria, DP | 1 |
| Mukhopadhyay, DK | 1 |
| Mehta, S | 1 |
| Mittal, D | 1 |
| Rao, YV | 1 |
| Malhotra, KK | 1 |
| Witjes, FJ | 1 |
| Debruyne, FM | 1 |
| Fernandez del Moral, P | 1 |
| Geboers, AD | 1 |
| Jubelirer, SJ | 1 |
| Hogan, T | 1 |
| Garciá-Girón, C | 1 |
| Artal, A | 1 |
| Garrido, P | 1 |
| González Barón, M | 1 |
| Hanash, KA | 1 |
| Tapazoglou, E | 1 |
| Subramanian, MG | 1 |
| Al-Sarraf, M | 1 |
| Kresge, C | 1 |
| Decker, DA | 1 |
| Vanuytsel, L | 1 |
| Ang, KK | 1 |
| Vantongelen, K | 1 |
| Drochmans, A | 1 |
| Baert, L | 1 |
| van der Schueren, E | 1 |
| Hassellund, S | 1 |
| Norman, N | 1 |
| Sander, S | 1 |
| Lowe, FC | 1 |
| Somers, WJ | 1 |
| Smith, JB | 1 |
| Ghayad, PY | 1 |
| Dhabuwala, CB | 1 |
| Drelichman, A | 1 |
| Pierce, JM | 1 |
| Feldman, LD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mechanisms of Control of the Intratesticular Hormonal Milieu in Man[NCT01215292] | Phase 1/Phase 2 | 46 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| A Randomized Phase II Trial of Taxol/VP-16/Estramustine vs. Ketoconazole/Doxorubicin/Vinblastine/Estramustine in Androgen Independent Prostate Cancer[NCT00003084] | Phase 2 | 75 participants (Actual) | Interventional | 1997-12-31 | Completed | ||
| A Phase III Randomized Trial for Evaluating Second Line Hormonal Therapy (Ketoconazole/Hydrocortisone) Versus Paclitaxel/Estramustine Combination Chemotherapy on Progression Free Survival in Asymptomatic Patients With a Rising PSA After Hormonal Therapy f[NCT00027859] | Phase 3 | 0 participants | Interventional | 2003-10-08 | Completed | ||
| A PHASE III TWO-ARM RANDOMIZED STUDY COMPARING ANTIANDROGEN WITHDRAWAL ALONE VERSUS ANTIANDROGEN WITHDRAWAL COMBINED WITH KETOCONAZOLE AND HYDROCORTISON IN PATIENTS WITH ADVANCED PROSTAGE CANCER[NCT00002760] | Phase 3 | 260 participants (Actual) | Interventional | 1996-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel (Tgel)+ Placebo | .87 |
| Acyline + Tgel + Ketoconazole 400mg | 0.5 |
| Acyline + Tgel + Ketoconazole 800mg | 0.12 |
| Acyline & TGel & Dutasteride 2.5mg | 1.7 |
| Acyline & TGel & Anastrazole 1mg | 3.6 |
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel (Tgel)+ Placebo | 3.17 |
| Acyline & TGel & Ketoconazole 400 mg | 2.08 |
| Acyline & TGel & Ketoconazole 800 mg | 1.46 |
| Acyline & TGel & Dutasteride | 0.12 |
| Acyline & TGel & Anastrazole | 3.63 |
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel + Placebo | 14 |
| Acyline + Tgel + Ketoconazole 400mg | 3.7 |
| Acyline + Tgel + Ketoconazole 800mg | 1.7 |
| Acyline & TGel & Dutasteride 2.5mg | 18.4 |
| Acyline & TGel & Anastrazole 1mg | 24.0 |
5 reviews available for ketoconazole and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
P450-dependent enzymes as targets for prostate cancer therapy.
Topics: Adenocarcinoma; Aldehyde-Lyases; Androgen Antagonists; Androgens; Animals; Antineoplastic Agents, Ho | 1996 |
Ketoconazole-induced adrenal crisis in a patient with metastatic prostatic adenocarcinoma: case report and review of the literature.
Topics: Adenocarcinoma; Adrenal Gland Diseases; Aged; Bone Neoplasms; Humans; Ketoconazole; Male; Prostatic | 1997 |
Endocrine therapy of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Antineoplasti | 1998 |
[Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative].
Topics: Adenocarcinoma; Antineoplastic Agents; Biopsy, Needle; Blood Coagulation Tests; Diethylstilbestrol; | 1991 |
High dose ketoconazole for the treatment of hormone refractory metastatic prostate carcinoma: 16 cases and review of the literature.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Diethylstilbestrol; Humans; Ketoconazole; Male; Middle Aged | 1989 |
6 trials available for ketoconazole and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Bone-targeted therapy: phase II study of strontium-89 in combination with alternating weekly chemohormonal therapies for patients with advanced androgen-independent prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antifungal Agents; Antineoplastic Combined Chemotherapy Pro | 2008 |
Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Antineoplastic Agents, Hor | 2011 |
Randomized, multicenter, phase II trial of two multicomponent regimens in androgen-independent prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin | 2003 |
Phase 3 randomized trial evaluating second-line hormonal therapy versus docetaxel-estramustine combination chemotherapy on progression-free survival in asymptomatic patients with a rising prostate-specific antigen level after hormonal therapy for prostate
Topics: Adenocarcinoma; Adult; Aged; Androgen Antagonists; Anticoagulants; Antineoplastic Agents, Hormonal; | 2003 |
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined | 2004 |
Ketoconazole high dose in management of hormonally pretreated patients with progressive metastatic prostate cancer. Dutch South-Eastern Urological Cooperative Group.
Topics: Acid Phosphatase; Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Clinical Trials as | 1989 |
38 other studies available for ketoconazole and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tum | 2013 |
An improved and versatile immunosuppression protocol for the development of tumor xenograft in mice.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cyclophosphamide; Cyclosporine; Cytochrome P-450 CYP3A In | 2014 |
Strategies to Circumvent Testosterone Surge and Disease Flare in Advanced Prostate Cancer: Emerging Treatment Paradigms.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Gonadotropin-Releasing Hormone; Humans; Ketoc | 2015 |
Singapore Cancer Network (SCAN) Guidelines for the Management of Advanced Castrate-Resistant Prostate Cancer.
Topics: Adenocarcinoma; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Cancer Vaccine | 2015 |
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcitriol; Cell Line, Tumo | 2011 |
[Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma].
Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aged; Antineoplastic Combined Chemotherapy | 2011 |
Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration.
Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Humans; Ketoconazole; Male; P | 2011 |
Radiation port dermatophytosis: tinea corporis occurring at the site of irradiated skin.
Topics: Adenocarcinoma; Aged; Antifungal Agents; Humans; Ketoconazole; Male; Prostatic Neoplasms; Radioderma | 2012 |
Low dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen independent prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Biomarkers, Tumor; Disease | 2002 |
Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Pro | 2002 |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Animals; Antineoplastic Agents; Dinoprostone; Humans; | 2002 |
National Cancer Institute intramural approach to advanced prostate cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Biomedical Research; Cancer Vaccines; Clinical Trials as Topi | 2002 |
Prostate cancer metastasis to supraclavicular lymph node.
Topics: Acid Phosphatase; Adenocarcinoma; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Prot | 2004 |
[Mediastinal lymph nodes during the course of a metastatic prostate cancer].
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols; Bon | 2007 |
Efficacy of low-dose ketoconazole in hormone refractory prostate cancer patients at the National Cancer Centre and The Cancer Institute, Singapore.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Humans; Ketoconazole; Male | 2007 |
The effects of ketoconazole on testosterone production and normal and malignant androgen dependent tissues of the adult rat.
Topics: Adenocarcinoma; Animals; Castration; Depression, Chemical; Gonadotropin-Releasing Hormone; Half-Life | 1984 |
Combined treatment with ketoconazole and luteinising hormone releasing hormone analogue: a novel approach to resistant progressive prostatic cancer.
Topics: Adenocarcinoma; Aged; Drug Resistance; Drug Therapy, Combination; Gonadotropin-Releasing Hormone; Go | 1983 |
Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dexameth | 1994 |
Azole antifungals: weak inhibitors of inducible nitric oxide synthase in mouse and human cells.
Topics: Adenocarcinoma; Adult; Animals; Antifungal Agents; Azoles; Candida albicans; Colorectal Neoplasms; E | 1997 |
Ketoconazole-induced apoptosis through P53-dependent pathway in human colorectal and hepatocellular carcinoma cell lines.
Topics: Adenocarcinoma; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Hepato | 1998 |
[Paraneoplastic hypercorticism associated with a bronchial adenocarcinoma].
Topics: Adenocarcinoma; Aged; Antifungal Agents; Cushing Syndrome; Humans; Ketoconazole; Lung Neoplasms; Mal | 1999 |
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma.
Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Adrenocorticotropic Hormone; Aged; Alkalosis; Comorbidity; C | 2001 |
Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements.
Topics: Adenocarcinoma; Alkynes; Animals; Breast Neoplasms; Calcitriol; Cell Division; Chlorocebus aethiops; | 2001 |
Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Breast Neoplasms; Cell | 1992 |
Prostate specific antigen for assessing response to ketoconazole and prednisone in patients with hormone refractory metastatic prostate cancer.
Topics: Adenocarcinoma; Antigens, Neoplasm; Biomarkers, Tumor; Drug Therapy, Combination; Humans; Ketoconazo | 1990 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neo | 1991 |
Ketoconazole for prostate cancer.
Topics: Adenocarcinoma; Humans; Ketoconazole; Male; Prostatic Neoplasms | 1990 |
Persistent Cushing's disease in a patient with invasive pituitary adenoma.
Topics: Adenocarcinoma; Adult; Combined Modality Therapy; Cushing Syndrome; Female; Humans; Hydrocortisone; | 1990 |
Inhibition of hepatic metastasis from a human pancreatic adenocarcinoma (RWP-2) in the nude mouse by prostacyclin, forskolin, and ketoconazole.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colforsin; Epoprostenol; Hu | 1990 |
Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Bone Neoplasms; Disseminated Intravascular Coagulation; Emergencies; Humans; K | 1989 |
[Control of adrenal adenocarcinoma and Cushing's syndrome with ketoconazole].
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Humans; Ketoconazole; Male | 1989 |
Neurologic complications of ketoconazole therapy for advanced prostatic cancer.
Topics: Adenocarcinoma; Aged; Brain Diseases; Humans; Ketoconazole; Male; Prostatic Neoplasms; Radiography | 1989 |
High-dose ketoconazole therapy in patients with metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Androstenedione; Combined Modality Therapy; Dehydroepiandrosterone; Dexamethas | 1986 |
Ketoconazole therapy for advanced prostatic cancer: feasibility and treatment results.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Asthenia; Drug Administration Schedule; Drug Eruptions; Fea | 1987 |
Ketoconazole high dose in the hormonal treatment of advanced carcinoma of the prostate. A pilot study.
Topics: Adenocarcinoma; Aged; Androgens; Hormones; Humans; Ketoconazole; Male; Pilot Projects; Prostatic Neo | 1987 |
The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer.
Topics: Adenocarcinoma; Aged; Disseminated Intravascular Coagulation; Emergencies; Humans; Ketoconazole; Mal | 1987 |
The effects of cyclophosphamide, ketoconazole, aclacinomycin-A, methotrexate, and scheduled methotrexate-5-fluorouracil combination chemotherapy on the transplantable R-3327 prostatic adenocarcinoma in the F1 hybrid male rat.
Topics: Aclarubicin; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphami | 1985 |
Ketoconazole for male metastatic breast cancer.
Topics: Adenocarcinoma; Breast Neoplasms; Humans; Ketoconazole; Male; Middle Aged | 1986 |