ketoconazole has been researched along with AIDS-Related Complex in 3 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
AIDS-Related Complex: A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomised, double-blind study the efficacy and toxicity of oral fluconazole 50 mg daily and ketoconazole 200 mg daily were compared for the treatment of oropharyngeal candidiasis in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC)." | 5.06 | Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS. ( Clumeck, N; De Wit, S; Goossens, H; Weerts, D, 1989) |
| "Ketoconazole was administered po in order to block adrenal steroidogenesis, the drug caused a remarkable fall of cortisol serum concentrations, but was unable to modify significantly the immunological pattern of the patient." | 1.28 | Hormonal and immunological pattern in a patient with acquired immunodeficiency syndrome related complex and Cushing's syndrome. ( De Mercato, R; Ghiggi, MR; Giuliani, M; Lombardi, G; Panza, N; Rezza, G; Rossi, R; Suligoi, B; Tommaselli, AP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rossi, R | 1 |
| Tommaselli, AP | 1 |
| Panza, N | 1 |
| Ghiggi, MR | 1 |
| Rezza, G | 1 |
| Giuliani, M | 1 |
| Suligoi, B | 1 |
| De Mercato, R | 1 |
| Lombardi, G | 1 |
| De Wit, S | 1 |
| Weerts, D | 1 |
| Goossens, H | 1 |
| Clumeck, N | 1 |
| Wishner, AJ | 1 |
| Teplitz, ED | 1 |
| Goodman, DS | 1 |
1 trial available for ketoconazole and AIDS-Related Complex
| Article | Year |
|---|---|
Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Aged; AIDS-Related Complex; Candidi | 1989 |
2 other studies available for ketoconazole and AIDS-Related Complex
| Article | Year |
|---|---|
Hormonal and immunological pattern in a patient with acquired immunodeficiency syndrome related complex and Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; AIDS-Related Complex; Cushing Syndrome; Hum | 1992 |
Pityrosporum, ketoconazole, and seborrheic dermatitis.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dermatitis, Seborrheic; Humans; Ketoconazo | 1987 |