ketanserin has been researched along with Supranuclear Palsy, Progressive in 2 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stamelou, M | 1 |
| Matusch, A | 1 |
| Elmenhorst, D | 1 |
| Hurlemann, R | 1 |
| Eggert, KM | 1 |
| Zilles, K | 1 |
| Oertel, WH | 1 |
| Höglinger, GU | 1 |
| Bauer, A | 1 |
| Maloteaux, JM | 1 |
| Laterre, EC | 1 |
| Laduron, PM | 1 |
| Javoy-Agid, F | 1 |
| Agid, Y | 1 |
2 other studies available for ketanserin and Supranuclear Palsy, Progressive
| Article | Year |
|---|---|
Nigrostriatal upregulation of 5-HT2A receptors correlates with motor dysfunction in progressive supranuclear palsy.
Topics: Aged; Brain Mapping; Corpus Striatum; Female; Fluorine Radioisotopes; Humans; Ketanserin; Magnetic R | 2009 |
Decrease of serotonin-S2 receptors in temporal cortex of patients with Parkinson's disease and progressive supranuclear palsy.
Topics: Aged; Aged, 80 and over; Dementia; Humans; Ketanserin; Middle Aged; Parkinson Disease; Receptors, Se | 1988 |