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ketanserin and Subarachnoid Hemorrhage

ketanserin has been researched along with Subarachnoid Hemorrhage in 5 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"After subarachnoid hemorrhage, a pronounced network of serotonin-immunoreactive nerve fibers was demonstrated in the vessel wall."1.28Uptake and release of serotonin in rat cerebrovascular nerves after subarachnoid hemorrhage. ( Emilsson, K; Hardebo, JE; Nystedt, S; Owman, C; Szabò, C, 1992)
"The subarachnoid hemorrhage was induced by injecting arterial blood in the cisterna magna."1.28Effects of subarachnoid hemorrhage on platelet-derived vasoconstriction of rabbit basilar artery. ( Kassell, NF; Tanaka, Y; Torner, JC, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tagari, PC1
Kaye, AH1
Teddy, PJ1
Schachter, M1
Adams, CB1
Boullin, DJ1
Tsuji, T2
Cook, DA1
Orz, YI1
Aoki, T1
Yen, Y1
Chiba, S1
Kobayashi, S1
Szabò, C1
Emilsson, K1
Hardebo, JE1
Nystedt, S1
Owman, C1
Tanaka, Y1
Kassell, NF1
Torner, JC1

Other Studies

5 other studies available for ketanserin and Subarachnoid Hemorrhage

ArticleYear
The 5-hydroxytryptamine antagonist ketanserin inhibits the vasoconstrictor activity of per-operative CSF, from subarachnoid haemorrhage patients, on isolated tissues.
    Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:3

    Topics: Adult; Aged; Animals; Female; Humans; Hydroxyindoleacetic Acid; Intracranial Aneurysm; Intraoperativ

1983
Effect of ketanserin on 5-hydroxytryptamine-induced constriction in isolated, perfused canine basilar arteries exposed to blood.
    Acta neurochirurgica, 1996, Volume: 138, Issue:9

    Topics: Animals; Basilar Artery; Dogs; Ischemic Attack, Transient; Ketanserin; Perfusion; Potassium Chloride

1996
Effects of oxyhemoglobin on vasoconstriction in response to 5-hydroxytryptamine in isolated, perfused canine basilar arteries.
    Neurosurgery, 1998, Volume: 43, Issue:5

    Topics: Animals; Basilar Artery; Dogs; Dose-Response Relationship, Drug; Ketanserin; Oxyhemoglobins; Recepto

1998
Uptake and release of serotonin in rat cerebrovascular nerves after subarachnoid hemorrhage.
    Stroke, 1992, Volume: 23, Issue:1

    Topics: Animals; Basilar Artery; Electric Stimulation; Ischemic Attack, Transient; Ketanserin; Male; Oxidopa

1992
Effects of subarachnoid hemorrhage on platelet-derived vasoconstriction of rabbit basilar artery.
    Surgical neurology, 1989, Volume: 32, Issue:6

    Topics: Animals; Basilar Artery; Blood Platelets; Imidazoles; Indomethacin; Isometric Contraction; Ketanseri

1989