ketanserin has been researched along with Pregnancy in 68 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 9.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| "Ketanserin appears to be an attractive medicine in the treatment of severe hypertension in pregnancy, but the optimal dosage could not be established." | 9.10 | The optimal dosage of ketanserin for patients with severe hypertension in pregnancy. ( de Jeu, RM; Odendaal, HJ; Steyn, DW; van Geijn, HP; van Schie, DL, 2002) |
| "To compare the efficacy and safety of intravenous dihydralazine with ketanserin in the management of severe hypertension in the third trimester." | 9.08 | Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results. ( Odendaal, HJ; Steyn, DW, 1997) |
| "To compare the haemodynamic efficacy of ketanserin (a selective serotonin2-receptor blocker) with dihydralazine in the management of severe early-onset hypertension in pregnancy." | 9.08 | The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy. ( Bolte, AC; Dekker, GA; Strack van Schijndel, RJ; van Eyck, J; van Geijn, HP, 1998) |
| " We investigated the role of ketanserin, a selective serotonin-2-receptor antagonist, in lowering the rate of pre-eclampsia among pregnant women with mild to moderate hypertension." | 9.08 | Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997) |
| "To compare ketanserin with hydralazine in the treatment of hypertension in late pregnancy." | 9.08 | Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial. ( Howarth, G; Odendaal, HJ; Rossouw, HJ, 1995) |
| "We investigated the effect of peripheral serotonin receptor blockade on preeclamptic hypertension in 20 postpartum patients by the use of ketanserin, a serotonin receptor antagonist." | 9.05 | Control of preeclamptic hypertension by ketanserin, a new serotonin receptor antagonist. ( Socol, ML; Vaisrub, N; Weiner, CP, 1984) |
| "After completion of this article, the reader will be able to list the various drugs and their associated side effects that are used to treat hypertensive disorders during pregnancy; to describe the various effects of serotonin on the cardiovascular system; to summarize the literature concerning the use of ketanserin during pregnancy; and to list the potential uses of ketanserin in this setting." | 8.80 | Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin. ( Odendaal, HJ; Steyn, DW, 2000) |
| "1 nM) on isolated ovine uterine artery of late pregnancy, which were competitively antagonized by ketanserin." | 7.68 | Lysergic acid diethylamide is a partial agonist at 5-HT2 receptors in ovine uterine artery of late pregnancy. ( Dyer, DC; Zhang, L, 1993) |
| "Ketanserin is an attractive alternative in the management of severe early-onset preeclampsia." | 6.69 | Ketanserin versus dihydralazine in the management of severe early-onset preeclampsia: maternal outcome. ( Bolte, AC; Bruinse, HW; Dekker, GA; Kanhai, HH; van Eyck, J; van Geijn, HP, 1999) |
| "Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group." | 5.42 | [Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015) |
| "Ketanserin appears to be a better option than dihydralazine for treatment of severe preeclampsia since fewer maternal complications and side-effects were observed in patients receiving ketanserin." | 5.31 | Ketanserin for the treatment of preeclampsia. ( Bolte, AC; Dekker, GA; Gaffar, SF; van Eyck, J; van Geijn, HP, 2001) |
| "Oral ketanserin was used in an attempt to control gestational proteinuric hypertension and to improve perinatal outcome in 20 patients before 34 weeks." | 5.27 | [Oral ketanserin in the treatment of pre-eclampsia]. ( Hulme, VA; Odendaal, HJ, 1988) |
| "Ketanserin was administered intravenously as either 20 or 10 mg boluses to 16 patients with severe preeclampsia in labor." | 5.27 | Intrapartum treatment of preeclamptic hypertension by ketanserin. ( Hulme, VA; Odendaal, HJ, 1986) |
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 5.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| "Ketanserin is an antihypertensive drug that is increasingly being used parenterally in the treatment of pre-eclampsia." | 5.11 | Population pharmacokinetics of ketanserin in pre-eclamptic patients and its association with antihypertensive response. ( Hanff, LM; Steegers, EA; Visser, W; Vulto, AG, 2005) |
| "Ketanserin appears to be an attractive medicine in the treatment of severe hypertension in pregnancy, but the optimal dosage could not be established." | 5.10 | The optimal dosage of ketanserin for patients with severe hypertension in pregnancy. ( de Jeu, RM; Odendaal, HJ; Steyn, DW; van Geijn, HP; van Schie, DL, 2002) |
| "To compare the efficacy and safety of intravenous dihydralazine with ketanserin in the management of severe hypertension in the third trimester." | 5.08 | Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results. ( Odendaal, HJ; Steyn, DW, 1997) |
| "To compare the haemodynamic efficacy of ketanserin (a selective serotonin2-receptor blocker) with dihydralazine in the management of severe early-onset hypertension in pregnancy." | 5.08 | The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy. ( Bolte, AC; Dekker, GA; Strack van Schijndel, RJ; van Eyck, J; van Geijn, HP, 1998) |
| "To compare ketanserin with hydralazine in the treatment of hypertension in late pregnancy." | 5.08 | Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial. ( Howarth, G; Odendaal, HJ; Rossouw, HJ, 1995) |
| " We investigated the role of ketanserin, a selective serotonin-2-receptor antagonist, in lowering the rate of pre-eclampsia among pregnant women with mild to moderate hypertension." | 5.08 | Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997) |
| "We investigated the effect of peripheral serotonin receptor blockade on preeclamptic hypertension in 20 postpartum patients by the use of ketanserin, a serotonin receptor antagonist." | 5.05 | Control of preeclamptic hypertension by ketanserin, a new serotonin receptor antagonist. ( Socol, ML; Vaisrub, N; Weiner, CP, 1984) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "After completion of this article, the reader will be able to list the various drugs and their associated side effects that are used to treat hypertensive disorders during pregnancy; to describe the various effects of serotonin on the cardiovascular system; to summarize the literature concerning the use of ketanserin during pregnancy; and to list the potential uses of ketanserin in this setting." | 4.80 | Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin. ( Odendaal, HJ; Steyn, DW, 2000) |
| "Control and maternally separated litters received treatment with the 5-HT(2) receptor antagonist, ketanserin, or vehicle during postnatal life and were examined for effects on adult anxiety behavior, adult stress-induced immediate early gene expression responses, and transcriptional changes within the prefrontal cortex during postnatal life and in adulthood." | 3.77 | Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress. ( Benekareddy, M; Nair, AR; Vadodaria, KC; Vaidya, VA, 2011) |
| "The aim of this prospective, observational study was to assess transplacental transmission of ketanserin, an antihypertensive drug used in pre-eclampsia, and to determine disposition and effects in the neonate after maternal ketanserin use." | 3.72 | Ketanserin in pre-eclamptic patients: transplacental transmission and disposition in neonates. ( Bulsink, MJ; Hanff, LM; Roofthooft, DW; Steegers, EA; Vermes, A; Visser, W; Vulto, AG, 2004) |
| " Responses to ovalbumin of uterine tissues in rats sensitized to the antigen were highest at midpregnancy and decreased during the last 10 days of gestation." | 3.70 | Modulation of rat uterine contractility by mast cells and their mediators. ( Bytautiene, E; Garfield, RE; Marshall, JS; Romero, R; Vedernikov, YP, 2000) |
| " The role of inositol 1,4,5-trisphosphate (InsP3) in the reduced vascular responsiveness to 5-hydroxytryptamine (5-HT) caused by chronic hypoxia was examined in uterine arteries obtained from normoxic (control) and chronically hypoxic pregnant sheep (approximately 140 days gestation) maintained at high altitude (3820 m; arterial PO2, 60 mmHg) from 30 days gestation." | 3.69 | Chronic hypoxia suppresses pharmacomechanical coupling of the uterine artery in near-term pregnant sheep. ( Hu, XQ; Zhang, L, 1997) |
| "1 nM) on isolated ovine uterine artery of late pregnancy, which were competitively antagonized by ketanserin." | 3.68 | Lysergic acid diethylamide is a partial agonist at 5-HT2 receptors in ovine uterine artery of late pregnancy. ( Dyer, DC; Zhang, L, 1993) |
| "Ketanserin is an attractive alternative in the management of severe early-onset preeclampsia." | 2.69 | Ketanserin versus dihydralazine in the management of severe early-onset preeclampsia: maternal outcome. ( Bolte, AC; Bruinse, HW; Dekker, GA; Kanhai, HH; van Eyck, J; van Geijn, HP, 1999) |
| "The etiology of preeclampsia is still unknown." | 2.41 | Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers. ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001) |
| "Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group." | 1.42 | [Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015) |
| "Comparative study of the effects of chronic administration of 5-HT(2A/2C)-receptors agonist (m-CPP, 0." | 1.38 | [Behavioral effects of ketanserine in prenatally stressed female rats]. ( Fedotova, IuO; Ordian, NE; Pivina, SG, 2012) |
| "Maternal HELLP syndrome was diagnosed more often in hypotensive compared to normotensive neonates (P=." | 1.38 | The effect of maternal ketanserin use on the circulation of the neonate: a prospective, observational study. ( de Vries, NK; Morssink, LP; Schaafstra, L; van Roon, EN, 2012) |
| "Pretreatment with fasudil, a Rho kinase inhibitor, blunted the effects of 5-HT infusion." | 1.37 | Pulmonary vascular effects of serotonin and selective serotonin reuptake inhibitors in the late-gestation ovine fetus. ( Abman, SH; Delaney, C; Gien, J; Grover, TR; Roe, G, 2011) |
| "Pregnant women with preeclampsia have increased serotonin levels, suggesting a possible role of this amine in abnormal pregnancy." | 1.34 | Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels. ( Aranda, E; Downey, P; Giacaman, A; Mezzano, D; Romero, W; Salas, SP; Vío, CP, 2007) |
| " There was no dose-response relationship with the agonist." | 1.33 | Maternal aggression in Wistar rats: effect of 5-HT2A/2C receptor agonist and antagonist microinjected into the dorsal periaqueductal gray matter and medial septum. ( da Silva, SP; de Almeida, RM; de Oliveira, VP; Giovenardi, M; Stein, DJ, 2005) |
| "Ketanserin appears to be a better option than dihydralazine for treatment of severe preeclampsia since fewer maternal complications and side-effects were observed in patients receiving ketanserin." | 1.31 | Ketanserin for the treatment of preeclampsia. ( Bolte, AC; Dekker, GA; Gaffar, SF; van Eyck, J; van Geijn, HP, 2001) |
| "Ketanserin was administered intravenously as either 20 or 10 mg boluses to 16 patients with severe preeclampsia in labor." | 1.27 | Intrapartum treatment of preeclamptic hypertension by ketanserin. ( Hulme, VA; Odendaal, HJ, 1986) |
| "Ketanserin was the main component of tissue radioactivity." | 1.27 | Pharmacokinetics and tissue distribution of ketanserin in rat, rabbit and dog. ( Geerts, R; Hendriks, R; Heykants, J; Meuldermans, W; Michiels, M; Monbaliu, J; Woestenborghs, R, 1988) |
| "Oral ketanserin was used in an attempt to control gestational proteinuric hypertension and to improve perinatal outcome in 20 patients before 34 weeks." | 1.27 | [Oral ketanserin in the treatment of pre-eclampsia]. ( Hulme, VA; Odendaal, HJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (23.53) | 18.7374 |
| 1990's | 24 (35.29) | 18.2507 |
| 2000's | 18 (26.47) | 29.6817 |
| 2010's | 8 (11.76) | 24.3611 |
| 2020's | 2 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Bhat, AD | 1 |
| Keasler, PM | 1 |
| Kolluru, L | 1 |
| Dombrowski, MM | 1 |
| Palanisamy, A | 1 |
| Singh, PM | 1 |
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Fedotova, IuO | 2 |
| Pivina, SG | 2 |
| Akulova, VK | 1 |
| Ordian, NÉ | 2 |
| Bijvank, SW | 1 |
| Visser, W | 5 |
| Duvekot, JJ | 1 |
| Steegers, EA | 5 |
| Edens, MA | 1 |
| Roofthooft, DW | 2 |
| Vulto, AG | 5 |
| Hanff, LM | 5 |
| Bras, H | 1 |
| Gaytán, SP | 1 |
| Portalier, P | 1 |
| Zanella, S | 1 |
| Pásaro, R | 1 |
| Coulon, P | 1 |
| Hilaire, G | 1 |
| Delaney, C | 1 |
| Gien, J | 1 |
| Grover, TR | 1 |
| Roe, G | 1 |
| Abman, SH | 1 |
| Benekareddy, M | 1 |
| Vadodaria, KC | 1 |
| Nair, AR | 1 |
| Vaidya, VA | 1 |
| Goyal, R | 1 |
| Papamatheakis, DG | 1 |
| Loftin, M | 1 |
| Vrancken, K | 1 |
| Dawson, AS | 1 |
| Osman, NJ | 1 |
| Blood, AB | 1 |
| Pearce, WJ | 1 |
| Longo, LD | 1 |
| Wilson, SM | 1 |
| McOmish, CE | 1 |
| Gingrich, JA | 1 |
| Schaafstra, L | 1 |
| van Roon, EN | 1 |
| Morssink, LP | 1 |
| de Vries, NK | 1 |
| Adebiyi, A | 1 |
| Adaikan, GP | 1 |
| Prasad, RN | 1 |
| Banga, FR | 1 |
| Bolte, AC | 5 |
| Dekker, GA | 5 |
| van Geijn, HP | 6 |
| Bulsink, MJ | 1 |
| Vermes, A | 1 |
| de Almeida, RM | 1 |
| Giovenardi, M | 1 |
| da Silva, SP | 1 |
| de Oliveira, VP | 1 |
| Stein, DJ | 1 |
| Freerksen, N | 1 |
| Betancourt, A | 1 |
| Maul, H | 1 |
| Wentz, M | 1 |
| Orise, P | 1 |
| Günter, HH | 1 |
| Sohn, C | 1 |
| Vedernikov, Y | 1 |
| Saade, G | 1 |
| Garfield, R | 1 |
| Gupta, S | 2 |
| Saxena, PR | 2 |
| MaassenVanDenBrink, A | 2 |
| Gerendai, I | 1 |
| Banczerowski, P | 1 |
| Csernus, V | 1 |
| Halász, B | 1 |
| Salas, SP | 1 |
| Giacaman, A | 1 |
| Romero, W | 1 |
| Downey, P | 1 |
| Aranda, E | 1 |
| Mezzano, D | 1 |
| Vío, CP | 1 |
| Weiner, CP | 2 |
| Socol, ML | 2 |
| Vaisrub, N | 1 |
| Reiche, R | 1 |
| Frey, HH | 1 |
| Gelfan, R | 1 |
| Zhang, L | 4 |
| Hu, XQ | 3 |
| Rossouw, HJ | 1 |
| Howarth, G | 1 |
| Odendaal, HJ | 7 |
| Johansson-Wallsten, CE | 1 |
| Berg, M | 1 |
| Meyerson, BJ | 1 |
| Gao, BX | 1 |
| Ziskind-Conhaim, L | 1 |
| Dyer, DC | 4 |
| Gajraj, NM | 1 |
| Hutter, C | 1 |
| Schneider, TJ | 1 |
| Struijk, PC | 1 |
| Lotgering, FK | 1 |
| Wallenburg, HC | 1 |
| Steyn, DW | 4 |
| Watanabe, M | 1 |
| Kodama, Y | 1 |
| Hagino, Y | 1 |
| Nonaka, R | 1 |
| Kaichi, Y | 1 |
| van Eyck, J | 3 |
| Strack van Schijndel, RJ | 1 |
| Karlsson, C | 1 |
| Bodelsson, G | 1 |
| Bodelsson, M | 1 |
| Stjernquist, M | 1 |
| Kanhai, HH | 1 |
| Bruinse, HW | 1 |
| Jahn, GA | 2 |
| Kalia, V | 1 |
| Hole, D | 1 |
| Wilson, CA | 1 |
| Deis, RP | 2 |
| Fiorica-Howells, E | 1 |
| Maroteaux, L | 1 |
| Gershon, MD | 1 |
| Marcondes, S | 1 |
| Lafay, M | 1 |
| Brohard-Bohn, B | 1 |
| de Nucci, G | 1 |
| Rendu, F | 1 |
| Garfield, RE | 1 |
| Bytautiene, E | 1 |
| Vedernikov, YP | 1 |
| Marshall, JS | 1 |
| Romero, R | 1 |
| Gaffar, SF | 1 |
| van Schie, DL | 1 |
| de Jeu, RM | 1 |
| Reviriego, J | 3 |
| Fernandez-Alfonso, MS | 2 |
| Guerra, P | 1 |
| Marín, J | 3 |
| Furuhashi, N | 1 |
| Tsujiei, M | 1 |
| Kimura, H | 1 |
| Yajima, A | 1 |
| Hembrough, FB | 1 |
| Isla, M | 1 |
| Distler, A | 1 |
| Zmira, N | 1 |
| Manpach, M | 1 |
| Varon, D | 1 |
| Maymon, R | 1 |
| Bahary, C | 1 |
| Mistry, AM | 1 |
| Voogt, JL | 2 |
| Zhang, LB | 1 |
| Voto, LS | 1 |
| Zin, C | 1 |
| Neira, J | 1 |
| Lapidus, AM | 1 |
| Margulies, M | 1 |
| Mistry, A | 1 |
| Cruz, MA | 1 |
| Gonzalez, C | 1 |
| Acevedo, CG | 1 |
| Sepulveda, WH | 1 |
| Rudolph, MI | 1 |
| Montenegro, R | 1 |
| Knuppel, RA | 1 |
| Shah, D | 1 |
| O'Brien, WF | 1 |
| Hulme, VA | 2 |
| Weiss, S | 1 |
| Sebben, M | 2 |
| Kemp, DE | 1 |
| Bockaert, J | 2 |
| Breese, GR | 1 |
| Duncan, GE | 1 |
| Napier, TC | 1 |
| Bondy, SC | 1 |
| Iorio, LC | 1 |
| Mueller, RA | 1 |
| Vandeputte-Van Messon, G | 1 |
| Burvenich, C | 1 |
| Peeters, G | 1 |
| Michiels, M | 1 |
| Monbaliu, J | 1 |
| Meuldermans, W | 1 |
| Hendriks, R | 1 |
| Geerts, R | 1 |
| Woestenborghs, R | 1 |
| Heykants, J | 1 |
| Dumuis, A | 1 |
| Bouhelal, R | 1 |
5 reviews available for ketanserin and Pregnancy
| Article | Year |
|---|---|
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant | 2023 |
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Ketanserin; | 2000 |
Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diureti | 2001 |
Clinical aspects during therapy with the serotonin antagonist ketanserin.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Combinat | 1990 |
11 trials available for ketanserin and Pregnancy
| Article | Year |
|---|---|
Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Dihydralazine; Double-Blind Method; Female; Gestational Age; Hospita | 2015 |
Population pharmacokinetics of ketanserin in pre-eclamptic patients and its association with antihypertensive response.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension; Infusions, Intravenous; Ketanserin; Me | 2005 |
Control of preeclamptic hypertension by ketanserin, a new serotonin receptor antagonist.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Femal | 1984 |
Ketanserin and hydralazine in hypertension in pregnancy--a randomised double-blind trial.
Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Female; Humans; Hydralazine; Ketanserin; Pre | 1995 |
Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Hum | 1997 |
Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dihydralazine; Double-Blind Method; Female; Fetal De | 1997 |
The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Dihydralazine; Female; Heart Rate; H | 1998 |
Ketanserin versus dihydralazine in the management of severe early-onset preeclampsia: maternal outcome.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dihydralazine; Female; HELLP Syndrome; Humans; Ketan | 1999 |
The optimal dosage of ketanserin for patients with severe hypertension in pregnancy.
Topics: Adult; Antihypertensive Agents; Cesarean Section; Double-Blind Method; Female; Humans; Hypertension; | 2002 |
Ketanserin versus alpha-methyldopa in the treatment of hypertension during pregnancy: a preliminary report.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Fetus; Humans; Ketanserin; Methyldopa; Pre- | 1987 |
The effect of serotonergic blockade in postpartum preeclamptic patients.
Topics: Adult; Blood Pressure; Double-Blind Method; Female; Humans; Ketanserin; Piperidines; Pre-Eclampsia; | 1985 |
52 other studies available for ketanserin and Pregnancy
| Article | Year |
|---|---|
[Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats].
Topics: Animals; Behavior, Animal; Depression; Drug Administration Schedule; Drug Therapy, Combination; Estr | 2015 |
Prenatal activation of 5-HT2A receptor induces expression of 5-HT1B receptor in phrenic motoneurons and alters the organization of their premotor network in newborn mice.
Topics: Amphetamines; Animals; Animals, Newborn; Embryo, Mammalian; Female; Ketanserin; Mice; Mice, Inbred C | 2008 |
Pulmonary vascular effects of serotonin and selective serotonin reuptake inhibitors in the late-gestation ovine fetus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Female; Fe | 2011 |
Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Apoptosis Regulatory Proteins | 2011 |
Long-term maternal hypoxia: the role of extracellular Ca2+ entry during serotonin-mediated contractility in fetal ovine pulmonary arteries.
Topics: Animals; Calcium; Female; Fetus; Hypoxia; In Vitro Techniques; Ketanserin; Pregnancy; Pulmonary Arte | 2011 |
Stress and the baby brain.
Topics: Animals; Anxiety; Female; Gene Expression Regulation; Ketanserin; Male; Pregnancy; Prenatal Exposure | 2011 |
The effect of maternal ketanserin use on the circulation of the neonate: a prospective, observational study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; HELLP Syndrome; Humans; Infant, | 2012 |
[Behavioral effects of ketanserine in prenatally stressed female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Female; | 2012 |
Oxytocic activity of thrombin: modulation of thrombin-induced gravid rat myometrial contractions by 5-hydroxytryptamine receptor antagonists.
Topics: Animals; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Methysergide; Myometrium; Oxyto | 2004 |
Ketanserin in women with chronic hypertension and underlying thrombophilia.
Topics: Adult; Antihypertensive Agents; Female; Fetal Growth Retardation; HELLP Syndrome; Humans; Hypertensi | 2004 |
Ketanserin in pre-eclamptic patients: transplacental transmission and disposition in neonates.
Topics: Adult; Antihypertensive Agents; Female; Fetal Blood; Humans; Infant, Newborn; Ketanserin; Maternal-F | 2004 |
Maternal aggression in Wistar rats: effect of 5-HT2A/2C receptor agonist and antagonist microinjected into the dorsal periaqueductal gray matter and medial septum.
Topics: Aggression; Animals; Animals, Newborn; Female; Ketanserin; Male; Maternal Behavior; Microinjections; | 2005 |
PAR-2 activating peptide-induced stimulation of pregnant rat myometrium contractile activity partly involves the other membrane receptors.
Topics: Animals; Atropine; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hydraz | 2007 |
Functional reactivity of 5-HT receptors in human umbilical cord and maternal subcutaneous fat arteries after normotensive or pre-eclamptic pregnancy.
Topics: Adult; Arteries; Blood Pressure; Data Interpretation, Statistical; Female; Fetus; Humans; Ketanserin | 2006 |
Innervation and serotoninergic receptors of the testis interact with local action of interleukin-1beta on steroidogenesis.
Topics: Analysis of Variance; Animals; Drug Combinations; Female; Functional Laterality; Interleukin-1beta; | 2007 |
The effect of maternal ketanserin treatment on foetal 5-HT receptor function in umbilical cord artery of pre-eclamptic patients.
Topics: Adolescent; Adult; Antihypertensive Agents; Benzamides; Case-Control Studies; Dose-Response Relation | 2007 |
Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels.
Topics: 5-Hydroxytryptophan; Aldosterone; Animals; Blood Pressure; Creatinine; Disease Models, Animal; Femal | 2007 |
Antagonism of the 5-HT-induced bronchoconstriction in the cat.
Topics: Animals; Bronchi; Carbachol; Cats; Clenbuterol; Cyproheptadine; Female; Hemodynamics; Ketanserin; Ma | 1983 |
Intrapartum treatment of preeclamptic hypertension by ketanserin--a serotonin receptor antagonist.
Topics: Adult; Antihypertensive Agents; Delivery, Obstetric; Female; Humans; Hydralazine; Hypertension; Infa | 1984 |
Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium; Female; Inositol 1,4,5-Trisphosphate; Keta | 1995 |
The effects of long-term treatment with the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT2/1C receptor agonist DOI in the neonatal rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Dose-Response Relat | 1993 |
Development of chemosensitivity in serotonin-deficient spinal cords of rat embryos.
Topics: Animals; Female; Fenclonine; Ketanserin; Membrane Potentials; Motor Neurons; Pregnancy; Rats; Recept | 1993 |
Lysergic acid diethylamide is a partial agonist at 5-HT2 receptors in ovine uterine artery of late pregnancy.
Topics: Animals; Arteries; Female; In Vitro Techniques; Ketanserin; Lysergic Acid Diethylamide; Muscle Contr | 1993 |
Serotonin in pre-eclampsia.
Topics: Female; Humans; Ketanserin; Pre-Eclampsia; Pregnancy; Serotonin; Serotonin Antagonists | 1996 |
Placental transfer and maternal and fetal hemodynamic effects of ketanserin in the pregnant ewe.
Topics: Adrenergic alpha-Antagonists; Animals; Female; Fetus; Half-Life; Hemodynamics; Hydrogen-Ion Concentr | 1996 |
Chronic hypoxia suppresses pharmacomechanical coupling of the uterine artery in near-term pregnant sheep.
Topics: Animals; Female; Hypoxia; Inositol 1,4,5-Trisphosphate; Ketanserin; Muscle, Smooth, Vascular; Phenox | 1997 |
5-Hydroxytryptamine stimulates phosphoinositide hydrolysis and contraction in the ovine umbilical artery.
Topics: Animals; Female; In Vitro Techniques; Inositol Phosphates; Ketanserin; Muscle Contraction; Muscle, S | 1997 |
Effect of chronic amitriptyline administration on serotonergic receptors in rats with methylazoxymethanol-induced microencephaly.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkylating Agents; Amitriptyline; Animals; Antidepressive Ag | 1998 |
Characterization of 5-hydroxytryptamine receptors mediating circular smooth muscle contraction in the human umbilical artery.
Topics: Adolescent; Adult; Female; Humans; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth; Pre | 1999 |
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergi | 1999 |
Serotonin and the 5-HT(2B) receptor in the development of enteric neurons.
Topics: Age Factors; Amphetamines; Animals; Antibodies; Antigens, Differentiation; Cell Differentiation; Cel | 2000 |
Platelets induce human umbilical vein endothelial cell proliferation through P-selectin.
Topics: Aspirin; Blood Platelets; Cell Adhesion; Cell Division; Cell Line; Endothelium, Vascular; Female; Hu | 2000 |
Modulation of rat uterine contractility by mast cells and their mediators.
Topics: Animals; Antibodies, Anti-Idiotypic; Blood; Carbachol; Female; Histamine; Immunoglobulin E; Ketanser | 2000 |
Ketanserin for the treatment of preeclampsia.
Topics: Antihypertensive Agents; Aspartate Aminotransferases; Delivery, Obstetric; Dihydralazine; Female; Ge | 2001 |
Effects of Ca2+ antagonists nifedipine and diltiazem on isolated human chorionic arteries and veins.
Topics: Arteries; Calcium; Calcium Radioisotopes; Diltiazem; Female; Humans; In Vitro Techniques; Ketanserin | 1990 |
Effects of ketanserin--a serotonin receptor antagonist--on placental blood flow, placental weight and fetal weight of spontaneously hypertensive rats and normal Wistar Kyoto rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Fetus; Hydrogen; Ketanserin; Plac | 1991 |
Effect of R(-)2,5-dimethoxy-4-methylamphetamine on uterine and umbilical blood flow in conscious pregnant sheep.
Topics: Animals; Arteries; Blood Flow Velocity; Blood Pressure; DOM 2,5-Dimethoxy-4-Methylamphetamine; Femal | 1991 |
Ability of ketanserin to block different receptors in human placental vessels.
Topics: Female; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Ketanserin; Muscle Contractio | 1990 |
Evaluation of ketanserin as a tocolytic agent in third trimester pregnant rats.
Topics: Animals; Bradycardia; Female; Ketanserin; Pregnancy; Pregnancy, Animal; Rats; Serotonin Antagonists; | 1991 |
Serotonin synthesis inhibition or receptor antagonism reduces pregnancy-induced nocturnal prolactin secretion.
Topics: Analysis of Variance; Animals; Biogenic Monoamines; Dorsomedial Hypothalamic Nucleus; Dose-Response | 1990 |
Characterization of serotonergic receptors mediating contraction of ovine umbilical artery.
Topics: Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Female; In Vitro Techniques; Ketanserin; Piperazines | 1990 |
Role of serotonin in nocturnal and diurnal surges of prolactin in the pregnant rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Circadian Rhythm; Dopamine; Ergolines; Female; Fenclonine; | 1989 |
Effects of 5-hydroxytryptamine on human isolated placental chorionic arteries and veins.
Topics: Arteries; Calcium; Calcium Radioisotopes; Female; Humans; In Vitro Techniques; Ketanserin; Methyserg | 1989 |
Effects of histamine and serotonin on the contractility of isolated pregnant and nonpregnant human myometrium.
Topics: Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Humans; In Vitro | 1989 |
Intrapartum treatment of preeclamptic hypertension by ketanserin.
Topics: Blood Pressure; Female; Fetal Heart; Heart Rate; Humans; Hypertension; Ketanserin; Obstetric Labor C | 1986 |
Effect of serotonin antagonists on prolactin and progesterone secretion in rats: evidence that the stimulatory and inhibitory actions of serotonin on prolactin release may be mediated through different receptors.
Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Fluoxetine; Indoles; Ketanserin; Pregnancy; Proest | 1988 |
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus S | 1986 |
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Ani | 1987 |
Effect of serotonin on the motility of smooth muscles in teats of lactating cows.
Topics: Animals; Cattle; Female; Ketanserin; Lactation; Mammary Glands, Animal; Methysergide; Mianserin; Mil | 1985 |
Pharmacokinetics and tissue distribution of ketanserin in rat, rabbit and dog.
Topics: Animals; Autoradiography; Dogs; Feces; Female; Ketanserin; Male; Maternal-Fetal Exchange; Milk; Preg | 1988 |
A 5-HT receptor in the central nervous system, positively coupled with adenylate cyclase, is antagonized by ICS 205 930.
Topics: Adenylyl Cyclases; Animals; Brain; Female; Indoles; Ketanserin; Male; Methiothepin; Mice; Pregnancy; | 1988 |
[Oral ketanserin in the treatment of pre-eclampsia].
Topics: Administration, Oral; Adolescent; Adult; Blood Pressure; Female; Humans; Ketanserin; Pre-Eclampsia; | 1988 |