ketanserin has been researched along with Parkinsonian Disorders in 2 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levodopa-induced dyskinesias (LIDs) are abnormal involuntary movements induced by the chronic use of levodopa (l-Dopa) limiting the quality of life of Parkinson's disease (PD) patients." | 1.37 | Brain 5-HT(2A) receptors in MPTP monkeys and levodopa-induced dyskinesias. ( Di Paolo, T; Morissette, M; Parent, M; Riahi, G, 2011) |
| "Well-formed visual hallucinations (VH) are common in patients with Parkinson's disease (PD)." | 1.36 | Increased 5-HT2A receptors in the temporal cortex of parkinsonian patients with visual hallucinations. ( Brotchie, JM; Darr, T; Fox, SH; Hazrati, LN; Huot, P; Johnston, TH; Pires, D; Visanji, NP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huot, P | 1 |
| Johnston, TH | 1 |
| Darr, T | 1 |
| Hazrati, LN | 1 |
| Visanji, NP | 1 |
| Pires, D | 1 |
| Brotchie, JM | 1 |
| Fox, SH | 1 |
| Riahi, G | 1 |
| Morissette, M | 1 |
| Parent, M | 1 |
| Di Paolo, T | 1 |
2 other studies available for ketanserin and Parkinsonian Disorders
| Article | Year |
|---|---|
Increased 5-HT2A receptors in the temporal cortex of parkinsonian patients with visual hallucinations.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Autoradiography; Female; Hallucinations; Humans; Keta | 2010 |
Brain 5-HT(2A) receptors in MPTP monkeys and levodopa-induced dyskinesias.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Bioge | 2011 |