ketanserin has been researched along with Nerve Pain in 10 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The involvement of opioid receptor activation in the antinociceptive effect of either fluvoxamine, a selective serotonin reuptake inhibitor, or serotonin (5-HT) on thermal hyperalgesia and mechanical allodynia in a model of neuropathic pain in mice induced by sciatic nerve ligation was examined." | 3.73 | Possible involvement of opioidergic systems in the antinociceptive effect of the selective serotonin reuptake inhibitors in sciatic nerve-injured mice. ( Kamei, J; Nozaki, C, 2006) |
| "The behavioral signs of cold allodynia in Sprague-Dawley (SD) rats were induced by a single injection of oxaliplatin (6 mg/kg, i." | 1.40 | Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats. ( Go, D; Kim, SK; Lee, JH; Li, DX; Min, BI; Quan, FS; Yoon, H, 2014) |
| "Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems." | 1.36 | Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S | 1 |
| Nakata, E | 1 |
| Morita, A | 1 |
| Mizuno, K | 1 |
| Yamamura, K | 1 |
| Kato, A | 1 |
| Ohashi, K | 1 |
| Patel, R | 1 |
| Dickenson, AH | 1 |
| Nishijima, CM | 1 |
| Ganev, EG | 1 |
| Mazzardo-Martins, L | 1 |
| Martins, DF | 1 |
| Rocha, LR | 1 |
| Santos, AR | 1 |
| Hiruma-Lima, CA | 1 |
| Lee, JH | 1 |
| Li, DX | 1 |
| Yoon, H | 1 |
| Go, D | 1 |
| Quan, FS | 1 |
| Min, BI | 1 |
| Kim, SK | 1 |
| Wang, D | 1 |
| Chen, T | 1 |
| Gao, Y | 1 |
| Quirion, R | 1 |
| Hong, Y | 1 |
| Barchini, J | 1 |
| Tchachaghian, S | 1 |
| Shamaa, F | 1 |
| Jabbur, SJ | 1 |
| Meyerson, BA | 1 |
| Song, Z | 1 |
| Linderoth, B | 1 |
| Saadé, NE | 1 |
| Obata, H | 1 |
| Saito, S | 1 |
| Sakurazawa, S | 1 |
| Sasaki, M | 1 |
| Usui, T | 1 |
| Goto, F | 1 |
| Nitanda, A | 1 |
| Yasunami, N | 1 |
| Tokumo, K | 1 |
| Fujii, H | 1 |
| Hirai, T | 1 |
| Nishio, H | 1 |
| Nozaki, C | 1 |
| Kamei, J | 1 |
| Davies, JA | 1 |
| Beswick, T | 1 |
| Dickson, G | 1 |
10 other studies available for ketanserin and Nerve Pain
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, | 2010 |
Modality selective roles of pro-nociceptive spinal 5-HT
Topics: Animals; Disease Models, Animal; Ketanserin; Male; Membrane Potentials; Neural Pathways; Neuralgia; | 2018 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci | 2014 |
Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats.
Topics: Acupuncture Analgesia; Acupuncture Points; Animals; Apitherapy; Bee Venoms; Cold Temperature; Fenclo | 2014 |
Inhibition of SNL-induced upregulation of CGRP and NPY in the spinal cord and dorsal root ganglia by the 5-HT(2A) receptor antagonist ketanserin in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Denervation; Disease Models, Animal; Ganglia, Spinal; Hype | 2012 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; | 2012 |
Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury.
Topics: Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Ligation; Lumbar Vertebrae; Male; Ne | 2004 |
Contribution of the peripheral 5-HT 2A receptor to mechanical hyperalgesia in a rat model of neuropathic pain.
Topics: Animals; Binding Sites; Binding, Competitive; Denervation; Disease Models, Animal; Drug Interactions | 2005 |
Possible involvement of opioidergic systems in the antinociceptive effect of the selective serotonin reuptake inhibitors in sciatic nerve-injured mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fluvoxamine; Hyperalgesia; Injections, Spinal | 2006 |
Ketanserin and guanethidine in the treatment of causalgia.
Topics: Administration, Oral; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Ketanserin; | 1987 |