ketanserin has been researched along with Morphine Abuse in 3 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 mg/kg, twice daily for 9 days) suppressed the development of morphine dependence as assessed by naloxone (2 mg/kg)-precipitated withdrawal jumps and diarrhea on day 10 of testing." | 7.70 | Ketanserin reverses dizocilpine-suppression of morphine dependence but not tolerance in mice. ( Kulkarni, SK; Ninan, I, 2000) |
| "2 mg/kg, twice daily for 9 days) suppressed the development of morphine dependence as assessed by naloxone (2 mg/kg)-precipitated withdrawal jumps and diarrhea on day 10 of testing." | 3.70 | Ketanserin reverses dizocilpine-suppression of morphine dependence but not tolerance in mice. ( Kulkarni, SK; Ninan, I, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beubler, E | 1 |
| Bukhave, K | 1 |
| Rask-Madsen, J | 1 |
| Ninan, I | 1 |
| Kulkarni, SK | 1 |
| Neal, BS | 1 |
| Sparber, SB | 1 |
3 other studies available for ketanserin and Morphine Abuse
| Article | Year |
|---|---|
Colonic secretion mediated by prostaglandin E2 and 5-hydroxytryptamine may contribute to diarrhea due to morphine withdrawal in the rat.
Topics: Animals; Atropine; Clonidine; Colon; Cyclic AMP; Diarrhea; Dinoprostone; Female; Humans; Indomethaci | 1984 |
Ketanserin reverses dizocilpine-suppression of morphine dependence but not tolerance in mice.
Topics: Animals; Dizocilpine Maleate; Drug Combinations; Drug Tolerance; Excitatory Amino Acid Antagonists; | 2000 |
Ketanserin and pirenperone attenuate acute morphine withdrawal in rats.
Topics: Animals; Body Temperature; Conditioning, Operant; Ketanserin; Male; Morphine Dependence; Piperidines | 1986 |