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ketanserin and Lung Diseases, Obstructive

ketanserin has been researched along with Lung Diseases, Obstructive in 5 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"To indirectly test the hypothesis whether serotonin (5-HT) might have a role in the increase in pulmonary vascular resistance, we evaluated the haemodynamic and gas exchange response of intravenous ketanserin (K), a 5-HT receptor inhibitor, in eight severe but stable patients with chronic obstructive pulmonary disease with secondary pulmonary hypertension (mean pulmonary artery pressure (Ppa) 30."7.69Haemodynamic effects of ketanserin either alone or with oxygen in COPD patients with secondary pulmonary hypertension. ( Domenighetti, G; Feihl, F; Leuenberger, P, 1997)
"To indirectly test the hypothesis whether serotonin (5-HT) might have a role in the increase in pulmonary vascular resistance, we evaluated the haemodynamic and gas exchange response of intravenous ketanserin (K), a 5-HT receptor inhibitor, in eight severe but stable patients with chronic obstructive pulmonary disease with secondary pulmonary hypertension (mean pulmonary artery pressure (Ppa) 30."3.69Haemodynamic effects of ketanserin either alone or with oxygen in COPD patients with secondary pulmonary hypertension. ( Domenighetti, G; Feihl, F; Leuenberger, P, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cazzola, M3
Matera, MG1
D'Amato, G3
Rossi, F1
Domenighetti, G1
Leuenberger, P1
Feihl, F1
Guidetti, E1
Sepe, J2
Assogna, G2
Lucchetti, G1
Santangelo, G1
Hamet, A1
Král, B1
Cernohorský, D1
Lobefalo, G1
Guillaro, B1
Pietroletti, R1
Lauria, D1

Reviews

1 review available for ketanserin and Lung Diseases, Obstructive

ArticleYear
Effects of serotonin on airways: recent developments.
    Allergy, 1995, Volume: 50, Issue:1

    Topics: Allergy and Immunology; Animals; Bronchitis; Chronic Disease; Humans; Inflammation Mediators; Ketans

1995

Trials

2 trials available for ketanserin and Lung Diseases, Obstructive

ArticleYear
Acute respiratory and cardiovascular effects of inhaled ketanserin in chronic obstructive pulmonary disease. A comparative study with intravenously administered ketanserin.
    Chest, 1990, Volume: 97, Issue:4

    Topics: Administration, Inhalation; Adult; Aged; Blood Pressure; Double-Blind Method; Female; Forced Expirat

1990
Ketanserin, a new blocking agent of serotonin S2-receptors. Respiratory functional effects in chronic obstruction of the airways.
    Chest, 1987, Volume: 92, Issue:5

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expirator

1987

Other Studies

2 other studies available for ketanserin and Lung Diseases, Obstructive

ArticleYear
Haemodynamic effects of ketanserin either alone or with oxygen in COPD patients with secondary pulmonary hypertension.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1997, Volume: 52, Issue:5

    Topics: Female; Hemodynamics; Humans; Hypertension, Pulmonary; Ketanserin; Lung Diseases, Obstructive; Male;

1997
Comparative effects of oxygen, nifedipine and ketanserin in hypoxic pulmonary hypertension.
    Cor et vasa, 1985, Volume: 27, Issue:6

    Topics: Adult; Carbon Dioxide; Cardiac Output; Female; Heart Rate; Humans; Hypertension, Pulmonary; Hypoxia;

1985