ketanserin has been researched along with Leg Ulcer in 7 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical ketanserin is a valuable therapy for difficult-to-treat leg ulcers." | 9.12 | Healing effect of ketanserin on chronic leg ulcers in patients with diabetes. ( Cauwenbergh, G; Kharfi, M; Paquet, P; Piérard, GE; Quatresooz, P; Vroome, V, 2006) |
| "Topical ketanserin is a valuable therapy for difficult-to-treat leg ulcers." | 5.12 | Healing effect of ketanserin on chronic leg ulcers in patients with diabetes. ( Cauwenbergh, G; Kharfi, M; Paquet, P; Piérard, GE; Quatresooz, P; Vroome, V, 2006) |
| "One trial met the inclusion criteria, which was a small trial that compared 2% ketanserin ointment in polyethylene glycol (PEG) with vehicle alone (PEG) control, changed twice a day in 40 participants with arterial leg ulcers." | 4.91 | Dressings and topical agents for arterial leg ulcers. ( Forster, R; Pagnamenta, F, 2015) |
| "The majority of leg ulcers are associated with circulation problems; poor blood return in the veins causes venous ulcers (around 70% of ulcers) and poor blood supply to the legs causes arterial ulcers (around 25% of ulcers)." | 2.44 | Dressings and topical agents for arterial leg ulcers. ( Bradley, MD; Nelson, EA, 2007) |
| "The majority of leg ulcers are associated with circulation problems; poor blood return in the veins causes venous ulcers (around 70% of ulcers) and poor blood supply to the legs causes arterial ulcers (around 25% of ulcers)." | 2.42 | Dressings and topical agents for arterial leg ulcers. ( Bradley, MD; Nelson, EA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forster, R | 1 |
| Pagnamenta, F | 1 |
| Nelson, EA | 2 |
| Bradley, MD | 2 |
| Quatresooz, P | 1 |
| Kharfi, M | 1 |
| Paquet, P | 1 |
| Vroome, V | 1 |
| Cauwenbergh, G | 1 |
| Piérard, GE | 1 |
| Cox, NH | 1 |
| Dufton, PA | 1 |
| Rooman, RP | 1 |
| Janssen, H | 1 |
| Rustin, MH | 1 |
| Bunker, CB | 1 |
| Dowd, PM | 1 |
3 reviews available for ketanserin and Leg Ulcer
| Article | Year |
|---|---|
Dressings and topical agents for arterial leg ulcers.
Topics: Administration, Topical; Arteries; Humans; Ketanserin; Leg Ulcer; Occlusive Dressings; Ointments; Pl | 2015 |
Dressings and topical agents for arterial leg ulcers.
Topics: Administration, Topical; Humans; Ketanserin; Leg Ulcer; Occlusive Dressings; Ointments; Platelet Agg | 2003 |
Dressings and topical agents for arterial leg ulcers.
Topics: Administration, Topical; Arteries; Humans; Ketanserin; Leg Ulcer; Occlusive Dressings; Ointments; Pl | 2007 |
2 trials available for ketanserin and Leg Ulcer
| Article | Year |
|---|---|
Healing effect of ketanserin on chronic leg ulcers in patients with diabetes.
Topics: Administration, Cutaneous; Aged; Chronic Disease; Diabetes Mellitus, Type 1; Diabetic Foot; Double-B | 2006 |
Ketanserin promotes wound healing: clinical and preclinical results.
Topics: Aged; Chronic Disease; Double-Blind Method; Female; Granulation Tissue; Humans; Ketanserin; Leg Ulce | 1991 |
2 other studies available for ketanserin and Leg Ulcer
| Article | Year |
|---|---|
Treatment of Raynaud's phenomenon with ketanserin.
Topics: Adolescent; Humans; Ketanserin; Leg Ulcer; Male; Piperidines; Scleroderma, Systemic | 1984 |
Chronic leg ulceration with livedoid vasculitis, and response to oral ketanserin.
Topics: Administration, Oral; Chronic Disease; Female; Humans; Ketanserin; Leg Ulcer; Middle Aged; Raynaud D | 1989 |