ketanserin has been researched along with Kernicterus in 1 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Kernicterus: A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe neonatal hyperbilirubinemia has been known to cause the clinical syndrome of kernicterus and a milder one the syndrome of bilirubin-induced neurologic dysfunction (BIND)." | 4.12 | Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin. ( Arauchi, R; Fukushima, M; Hashioka, S; Hayashida, M; Inagaki, M; Miura, S; Miyaoka, T; Oh-Nishi, A; Otsuki, K; Tsuchie, K; Tsumori, T; Wake, R, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miura, S | 1 |
| Tsuchie, K | 1 |
| Fukushima, M | 1 |
| Arauchi, R | 1 |
| Tsumori, T | 1 |
| Otsuki, K | 1 |
| Hayashida, M | 1 |
| Hashioka, S | 1 |
| Wake, R | 1 |
| Miyaoka, T | 1 |
| Inagaki, M | 1 |
| Oh-Nishi, A | 1 |
1 other study available for ketanserin and Kernicterus
| Article | Year |
|---|---|
Normalizing hyperactivity of the Gunn rat with bilirubin-induced neurological disorders via ketanserin.
Topics: Animals; Bilirubin; Humans; Hyperbilirubinemia; Kernicterus; Ketanserin; Rats; Rats, Gunn; Rats, Wis | 2022 |