ketanserin has been researched along with Intraocular Pressure in 12 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of topical ketanserin on intraocular pressure (IOP) in normotensive and hypertensive eyes was evaluated." | 9.07 | Effect of topical ketanserin administration on intraocular pressure. ( Costagliola, C; Iuliano, G; Mastropasqua, L; Rinaldi, M; Russo, V; Scibelli, G, 1993) |
| "We evaluated the effect of the antihypertensive drug ketanserin, a 5-HT antagonist, on intraocular pressure (IOP) in 20 patients with ocular hypertension." | 9.07 | Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients. ( Costagliola, C; Fasano, ML; Ferrara, LA; Mastropasqua, L; Scibelli, G, 1991) |
| "The effects of fluoxetine, which is a selective inhibitor of serotonin reuptake (SSRI) have been studied on the intraocular pressure (IOP) in the rabbit." | 7.70 | Effect of fluoxetine on intraocular pressure in the rabbit. ( Capone, D; Ciancaglini, M; Costagliola, C; Mastropasqua, L; Pisanti, N; Verolino, M, 2000) |
| "The effects of topical and intracameral serotonin and topical, intracameral and intravenous selective (5-HT2) serotonin antagonist, ketanserin, on the intraocular pressure (IOP) were studied in the rabbit." | 7.67 | Effect of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit. ( Krootila, K; Palkama, A; Uusitalo, H, 1987) |
| "5% eye drops on intraocular pressure and orbital blood flow in some healthy volunteers." | 5.09 | Color doppler imaging of ocular blood flow after topical ketanserin. ( Caramazza, R; Cellini, M, 1999) |
| "The effect of topical ketanserin on intraocular pressure (IOP) in normotensive and hypertensive eyes was evaluated." | 5.07 | Effect of topical ketanserin administration on intraocular pressure. ( Costagliola, C; Iuliano, G; Mastropasqua, L; Rinaldi, M; Russo, V; Scibelli, G, 1993) |
| "The effects of fluoxetine, which is a selective inhibitor of serotonin reuptake (SSRI) have been studied on the intraocular pressure (IOP) in the rabbit." | 3.70 | Effect of fluoxetine on intraocular pressure in the rabbit. ( Capone, D; Ciancaglini, M; Costagliola, C; Mastropasqua, L; Pisanti, N; Verolino, M, 2000) |
| "25% w/v solution by corneal and scleral applications, was found to lower intraocular pressure with four times more activity than its metabolite, ketanserinol." | 3.70 | The ocular pharmacokinetics of ketanserin and its metabolite, ketanserinol, in albino rabbits. ( Schoenwald, RD; Zhu, J, 2000) |
| "A series of ketanserin analogs were studied for their effects on intraocular pressure (IOP) recovery curve of rabbits infused with hypertonic saline." | 3.68 | Ocular hypotensive actions of serotonin antagonist-ketanserin analogs. ( Chiou, GC; Li, BH, 1992) |
| "The effects of topical and intracameral serotonin and topical, intracameral and intravenous selective (5-HT2) serotonin antagonist, ketanserin, on the intraocular pressure (IOP) were studied in the rabbit." | 3.67 | Effect of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit. ( Krootila, K; Palkama, A; Uusitalo, H, 1987) |
| "Ketanserin is a specific antagonist of 5-HT2 and 5-HT1c receptors." | 2.68 | Ocular hypotensive effect of topical ketanserin in timolol users. ( Carpineto, P; Ciancaglini, M; Costagliola, C; Mastropasqua, L, 1997) |
| "Methysergide seems to inhibit the response, probably acting via the 5-HT1-receptors." | 1.27 | Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye. ( Krootila, K; Palkama, A; Uusitalo, H, 1987) |
| "Ketanserin has been characterized as a relatively selective antagonist for serotonin (5-HT2) receptors." | 1.27 | Mechanism of the ocular hypotensive action of ketanserin. ( Burke, JA; Chang, FW; Potter, DE, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Costagliola, C | 6 |
| Iuliano, G | 2 |
| Rinaldi, M | 1 |
| Russo, V | 1 |
| Scibelli, G | 2 |
| Mastropasqua, L | 5 |
| Ciancaglini, M | 3 |
| Carpineto, P | 2 |
| Gallenga, PE | 1 |
| Cellini, M | 1 |
| Caramazza, R | 1 |
| Capone, D | 1 |
| Verolino, M | 1 |
| Pisanti, N | 1 |
| Schoenwald, RD | 1 |
| Zhu, J | 1 |
| Chiou, GC | 1 |
| Li, BH | 1 |
| Fasano, ML | 2 |
| Ferrara, LA | 2 |
| Krootila, K | 2 |
| Uusitalo, H | 2 |
| Palkama, A | 2 |
| Chang, FW | 1 |
| Burke, JA | 1 |
| Potter, DE | 1 |
6 trials available for ketanserin and Intraocular Pressure
| Article | Year |
|---|---|
Effect of topical ketanserin administration on intraocular pressure.
Topics: Administration, Topical; Adult; Aqueous Humor; Blood Pressure; Double-Blind Method; Female; Glaucoma | 1993 |
Ocular hypotensive effect of topical ketanserin in timolol users.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Cross-Over Studies; Double-Blind Method; Femal | 1997 |
Ocular hypotensive effect of ketanserin in patients with primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, | 1997 |
Color doppler imaging of ocular blood flow after topical ketanserin.
Topics: Administration, Topical; Aged; Arteries; Ciliary Body; Double-Blind Method; Eye; Female; Humans; Int | 1999 |
Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Glaucoma; Humans; Intraocular Pressure; Ketanse | 1991 |
Effects of ketanserin on intraocular pressure.
Topics: Adult; Blood Pressure; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Ket | 1990 |
6 other studies available for ketanserin and Intraocular Pressure
| Article | Year |
|---|---|
Effect of fluoxetine on intraocular pressure in the rabbit.
Topics: Administration, Topical; Animals; Antidepressive Agents; Diuresis; Female; Fluoxetine; Hydroxyindole | 2000 |
The ocular pharmacokinetics of ketanserin and its metabolite, ketanserinol, in albino rabbits.
Topics: Administration, Topical; Animals; Eye; Female; Intraocular Pressure; Ketanserin; Male; Rabbits; Sero | 2000 |
Ocular hypotensive actions of serotonin antagonist-ketanserin analogs.
Topics: Animals; Glaucoma; Intraocular Pressure; Ketanserin; Ocular Hypertension; Ocular Hypotension; Rabbit | 1992 |
Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye.
Topics: Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Blood Pressure; Eye Diseases; Eye Proteins; Fe | 1987 |
Effect of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit.
Topics: Anesthesia; Animals; Aqueous Humor; Eye; Eye Proteins; Female; Injections; Injections, Intravenous; | 1987 |
Mechanism of the ocular hypotensive action of ketanserin.
Topics: Animals; Blinking; Cats; Cebus; Eye; Female; Intraocular Pressure; Ketanserin; Male; Rabbits; Reflex | 1985 |