Page last updated: 2024-10-29

ketanserin and Hypotension

ketanserin has been researched along with Hypotension in 10 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Two patients developed profound hypotension approximately one hour after taking an initial oral dose of ketanserin 40 mg."7.67Profound hypotension after the first dose of ketanserin. ( Cameron, HA; Ramsay, LE; Waller, PC, 1987)
"Two patients developed profound hypotension approximately one hour after taking an initial oral dose of ketanserin 40 mg."3.67Profound hypotension after the first dose of ketanserin. ( Cameron, HA; Ramsay, LE; Waller, PC, 1987)
"Pretreatment with cyproheptadine (2."1.28Hypotension induced by growth-hormone-releasing peptide is mediated by mast cell serotonin release in the rat. ( Gabel, RA; Macia, RA; Matthews, WD; Reginato, MJ, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's5 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Perim, RR1
Kubilis, PS1
Seven, YB1
Mitchell, GS1
Vellinga, NA1
Veenstra, G1
Scorcella, C1
Koopmans, M1
van Roon, EN1
Ince, C1
Boerma, EC1
Egan, BM1
Stepniakowski, K1
Zweifler, AJ1
Lin, MT1
Chueh, FY1
Hsieh, MT1
Chen, CF1
Van Gelderen, EM1
Saxena, PR2
Macia, RA1
Gabel, RA1
Reginato, MJ1
Matthews, WD1
Roffe, C1
Tidmarsh, M1
Howlett, TA1
Wiggins, RC1
Glatfelter, A1
Campbell, AM1
Kunkel, RG1
Ulevitch, RJ1
Dhasmana, KM1
Banerjee, AK1
Waller, PC1
Cameron, HA1
Ramsay, LE1

Trials

2 trials available for ketanserin and Hypotension

ArticleYear
Effects of ketanserin on microcirculatory alterations in septic shock: An open-label pilot study.
    Journal of critical care, 2015, Volume: 30, Issue:6

    Topics: Adult; Aged; Capillaries; Female; Hemodynamics; Humans; Hypotension; Inflammation; Ketanserin; Male;

2015
Ketanserin's sympatholytic and serotonin2-receptor blocking actions precede the hypotensive effects.
    Journal of human hypertension, 1994, Volume: 8, Issue:1

    Topics: Double-Blind Method; Humans; Hypotension; Ketanserin; Male; Middle Aged; Placebos; Serotonin Antagon

1994

Other Studies

8 other studies available for ketanserin and Hypotension

ArticleYear
Hypoxia-induced hypotension elicits adenosine-dependent phrenic long-term facilitation after carotid denervation.
    Experimental neurology, 2020, Volume: 333

    Topics: Adenosine; Animals; Arterial Pressure; Blood Gas Analysis; Carotid Body; Denervation; Hypotension; H

2020
Antihypertensive effects of DL-tetrahydropalmatine: an active principle isolated from Corydalis.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:8

    Topics: Amphetamines; Analysis of Variance; Animals; Antihypertensive Agents; Berberine Alkaloids; Blood Pre

1996
Effect of N(G)-nitro-L-arginine methyl ester on the hypotensive and hypertensive responses to 5-hydroxytryptamine in pithed rats.
    European journal of pharmacology, 1992, Nov-10, Volume: 222, Issue:2-3

    Topics: Animals; Appetite Depressants; Arginine; Blood Pressure; Drug Interactions; Endothelium, Vascular; H

1992
Hypotension induced by growth-hormone-releasing peptide is mediated by mast cell serotonin release in the rat.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Analysis of Variance; Animals; Cimetidine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Sy

1990
Ketanserin overdose: a case report.
    Postgraduate medical journal, 1991, Volume: 67, Issue:791

    Topics: Adolescent; Bradycardia; Female; Humans; Hypotension; Ketanserin; Suicide, Attempted

1991
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
    Circulation research, 1985, Volume: 57, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autonomic Nervous System; Blood Platelets; Bradyc

1985
Hypotension and bradycardia after intrathecal ketanserin and phentolamine in the rat.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: Animals; Blood Pressure; Bradycardia; Female; Heart Rate; Hypotension; Injections, Spinal; Ketanseri

1989
Profound hypotension after the first dose of ketanserin.
    Postgraduate medical journal, 1987, Volume: 63, Issue:738

    Topics: Aged; Female; Heart Rate; Humans; Hypertension; Hypotension; Ketanserin; Male; Middle Aged

1987