ketanserin has been researched along with Heart Disease, Ischemic in 8 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that ketanserin augments coronary collateral blood flow and decreases myocardial ischemia during balloon angioplasty." | 9.09 | Intracoronary ketanserin augments coronary collateral blood flow and decreases myocardial ischemia during balloon angioplasty. ( Antoniadis, A; Kremastinos, DT; Kyriakides, ZS; Nikolaou, N; Sbarouni, E, 1999) |
| "To test the hypothesis that ketanserin augments coronary collateral blood flow and decreases myocardial ischemia during balloon angioplasty." | 5.09 | Intracoronary ketanserin augments coronary collateral blood flow and decreases myocardial ischemia during balloon angioplasty. ( Antoniadis, A; Kremastinos, DT; Kyriakides, ZS; Nikolaou, N; Sbarouni, E, 1999) |
| "Myocardial ischemia was induced by a treadmill exercise test associated with limitation of left anterior descending coronary blood flow." | 1.32 | Serotonin aggravates exercise-induced cardiac ischemia in the dog: effect of serotonin receptor antagonists. ( Dubreuil, B; Guilbert, F; Herbert, JM; Janiak, P; Lainée, P; McCort, G; O'Connor, SE, 2004) |
| " Animals in groups 4 and 8 were given both lidoflazine and ketanserin according to the dosing schedules above." | 1.27 | Preservation of the ischemic canine myocardium: a comparison of hypothermia, lidoflazine, and ketanserin. ( Clark, NJ; McJames, SW; Pace, NL; Port, JD; Stanley, TH; Stockham, RJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guilbert, F | 1 |
| Lainée, P | 1 |
| Dubreuil, B | 1 |
| McCort, G | 1 |
| O'Connor, SE | 1 |
| Janiak, P | 1 |
| Herbert, JM | 1 |
| Clark, NJ | 1 |
| Port, JD | 1 |
| McJames, SW | 1 |
| Stockham, RJ | 1 |
| Stanley, TH | 1 |
| Pace, NL | 1 |
| Grover, GJ | 1 |
| Sargent, CA | 1 |
| Dzwonczyk, S | 1 |
| Normandin, DE | 1 |
| Antonaccio, MJ | 1 |
| Mitsuoka, W | 1 |
| Egashira, S | 1 |
| Tagawa, H | 1 |
| Kuga, T | 1 |
| Hayashi, Y | 1 |
| Yamada, A | 1 |
| Tomoike, H | 1 |
| Nakamura, M | 1 |
| Takeshita, A | 1 |
| Kaumann, AJ | 1 |
| Frenken, M | 1 |
| Posival, H | 1 |
| Brown, AM | 1 |
| Buus, NH | 1 |
| Terp, K | 1 |
| Baandrup, U | 1 |
| Mulvany, MJ | 1 |
| Nyborg, NC | 1 |
| Kyriakides, ZS | 1 |
| Sbarouni, E | 1 |
| Nikolaou, N | 1 |
| Antoniadis, A | 1 |
| Kremastinos, DT | 1 |
| Schad, H | 1 |
| Heimisch, W | 1 |
| Barankay, A | 1 |
| Hesse, S | 1 |
| Mendler, N | 1 |
1 trial available for ketanserin and Heart Disease, Ischemic
| Article | Year |
|---|---|
Intracoronary ketanserin augments coronary collateral blood flow and decreases myocardial ischemia during balloon angioplasty.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Collateral Circulation; Coronary Circulation; Coronar | 1999 |
7 other studies available for ketanserin and Heart Disease, Ischemic
| Article | Year |
|---|---|
Serotonin aggravates exercise-induced cardiac ischemia in the dog: effect of serotonin receptor antagonists.
Topics: Animals; Dogs; Endothelium, Vascular; Female; Hemodynamics; Hypercholesterolemia; Infusions, Intrave | 2004 |
Preservation of the ischemic canine myocardium: a comparison of hypothermia, lidoflazine, and ketanserin.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cardiopu | 1988 |
Protective effect of serotonin (5-HT2) receptor antagonists in ischemic rat hearts.
Topics: Animals; Cinanserin; Disease Models, Animal; Ergolines; Heart; Hemodynamics; Ketanserin; L-Lactate D | 1993 |
Augmentation of coronary responsiveness to serotonin at the site of X-ray-induced intimal thickening in miniature pigs.
Topics: Animals; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular; Histamine; Ketanserin; Male; M | 1995 |
Variable participation of 5-HT1-like receptors and 5-HT2 receptors in serotonin-induced contraction of human isolated coronary arteries. 5-HT1-like receptors resemble cloned 5-HT1D beta receptors.
Topics: Adult; Arteriosclerosis; Binding, Competitive; Cardiomyopathy, Dilated; Cloning, Molecular; Coronary | 1994 |
Pharmacological characterization of coronary small arteries from pigs with chronic ischaemic myocardial remodelling.
Topics: Acetylcholine; Animals; Bradykinin; Cardiomegaly; Cardiotonic Agents; Chronic Disease; Coronary Vess | 1998 |
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Heart; Hea | 1992 |