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ketanserin and Glaucoma

ketanserin has been researched along with Glaucoma in 3 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"The effect of topical ketanserin on intraocular pressure (IOP) in normotensive and hypertensive eyes was evaluated."9.07Effect of topical ketanserin administration on intraocular pressure. ( Costagliola, C; Iuliano, G; Mastropasqua, L; Rinaldi, M; Russo, V; Scibelli, G, 1993)
"We evaluated the effect of the antihypertensive drug ketanserin, a 5-HT antagonist, on intraocular pressure (IOP) in 20 patients with ocular hypertension."9.07Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients. ( Costagliola, C; Fasano, ML; Ferrara, LA; Mastropasqua, L; Scibelli, G, 1991)
"The effect of topical ketanserin on intraocular pressure (IOP) in normotensive and hypertensive eyes was evaluated."5.07Effect of topical ketanserin administration on intraocular pressure. ( Costagliola, C; Iuliano, G; Mastropasqua, L; Rinaldi, M; Russo, V; Scibelli, G, 1993)
"A series of ketanserin analogs were studied for their effects on intraocular pressure (IOP) recovery curve of rabbits infused with hypertonic saline."3.68Ocular hypotensive actions of serotonin antagonist-ketanserin analogs. ( Chiou, GC; Li, BH, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Costagliola, C2
Iuliano, G1
Rinaldi, M1
Russo, V1
Scibelli, G2
Mastropasqua, L2
Chiou, GC1
Li, BH1
Fasano, ML1
Ferrara, LA1

Trials

2 trials available for ketanserin and Glaucoma

ArticleYear
Effect of topical ketanserin administration on intraocular pressure.
    The British journal of ophthalmology, 1993, Volume: 77, Issue:6

    Topics: Administration, Topical; Adult; Aqueous Humor; Blood Pressure; Double-Blind Method; Female; Glaucoma

1993
Effect of oral ketanserin administration on intraocular pressure in glaucomatous patients.
    Experimental eye research, 1991, Volume: 52, Issue:5

    Topics: Administration, Oral; Adult; Blood Pressure; Female; Glaucoma; Humans; Intraocular Pressure; Ketanse

1991

Other Studies

1 other study available for ketanserin and Glaucoma

ArticleYear
Ocular hypotensive actions of serotonin antagonist-ketanserin analogs.
    Journal of ocular pharmacology, 1992,Spring, Volume: 8, Issue:1

    Topics: Animals; Glaucoma; Intraocular Pressure; Ketanserin; Ocular Hypertension; Ocular Hypotension; Rabbit

1992