ketanserin has been researched along with Gastric Ulcer in 4 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Excerpt | Relevance | Reference |
---|---|---|
"Risperidone pretreatment reverses the stress induced alteration in hexosamine, PGE(2) and microvascular permeability." | 1.37 | Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions. ( Krishnamurthy, S; Saxena, B; Singh, S, 2011) |
"When ketanserin was administered to rats, only ketanserin and none of the metabolites was detected in plasma, indicating that the parent drug is the pharmacologically active substance." | 1.27 | Pharmacokinetic evaluation of the in vitro and in vivo pharmacological profile of the major metabolites of ketanserin in the rat. ( Awouters, F; Heykants, J; Leysen, JE; Michiels, M; Schuurkes, J; Van Nueten, JM; Woestenborghs, R, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Nishijima, CM | 1 |
Ganev, EG | 1 |
Mazzardo-Martins, L | 1 |
Martins, DF | 1 |
Rocha, LR | 1 |
Santos, AR | 1 |
Hiruma-Lima, CA | 1 |
Saxena, B | 1 |
Krishnamurthy, S | 1 |
Singh, S | 1 |
Yoneda, M | 1 |
Taché, Y | 1 |
Heykants, J | 1 |
Michiels, M | 1 |
Woestenborghs, R | 1 |
Awouters, F | 1 |
Leysen, JE | 1 |
Schuurkes, J | 1 |
Van Nueten, JM | 1 |
4 other studies available for ketanserin and Gastric Ulcer
Article | Year |
---|---|
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci | 2014 |
Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions.
Topics: Animals; Antipsychotic Agents; Capillary Permeability; Dinoprostone; Disease Models, Animal; Dopamin | 2011 |
Potentiating interactions between medullary serotonin and thyrotropin-releasing hormone-induced gastric erosions in rats.
Topics: Animals; Cold Temperature; Indomethacin; Injections; Injections, Intravenous; Ketanserin; Male; Medu | 1993 |
Pharmacokinetic evaluation of the in vitro and in vivo pharmacological profile of the major metabolites of ketanserin in the rat.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cricetinae; In Vitro Techniques | 1988 |