Page last updated: 2024-10-29

ketanserin and Gastric Ulcer

ketanserin has been researched along with Gastric Ulcer in 4 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Risperidone pretreatment reverses the stress induced alteration in hexosamine, PGE(2) and microvascular permeability."1.37Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions. ( Krishnamurthy, S; Saxena, B; Singh, S, 2011)
"When ketanserin was administered to rats, only ketanserin and none of the metabolites was detected in plasma, indicating that the parent drug is the pharmacologically active substance."1.27Pharmacokinetic evaluation of the in vitro and in vivo pharmacological profile of the major metabolites of ketanserin in the rat. ( Awouters, F; Heykants, J; Leysen, JE; Michiels, M; Schuurkes, J; Van Nueten, JM; Woestenborghs, R, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishijima, CM1
Ganev, EG1
Mazzardo-Martins, L1
Martins, DF1
Rocha, LR1
Santos, AR1
Hiruma-Lima, CA1
Saxena, B1
Krishnamurthy, S1
Singh, S1
Yoneda, M1
Taché, Y1
Heykants, J1
Michiels, M1
Woestenborghs, R1
Awouters, F1
Leysen, JE1
Schuurkes, J1
Van Nueten, JM1

Other Studies

4 other studies available for ketanserin and Gastric Ulcer

ArticleYear
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci

2014
Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions.
    Chemico-biological interactions, 2011, Apr-25, Volume: 190, Issue:2-3

    Topics: Animals; Antipsychotic Agents; Capillary Permeability; Dinoprostone; Disease Models, Animal; Dopamin

2011
Potentiating interactions between medullary serotonin and thyrotropin-releasing hormone-induced gastric erosions in rats.
    Neuroscience letters, 1993, Oct-29, Volume: 161, Issue:2

    Topics: Animals; Cold Temperature; Indomethacin; Injections; Injections, Intravenous; Ketanserin; Male; Medu

1993
Pharmacokinetic evaluation of the in vitro and in vivo pharmacological profile of the major metabolites of ketanserin in the rat.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cricetinae; In Vitro Techniques

1988