Page last updated: 2024-10-29

ketanserin and Fibrosarcoma

ketanserin has been researched along with Fibrosarcoma in 4 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The hepatic lodgement of intraportally injected fibrosarcoma cells was analysed with a combination of vital fluorescence microscopic, electron microscopic and isotope techniques in normal, thrombocytopenic and antiserotonin treated (Ketanserin) rats."3.66The effect of thrombocytopenia and antiserotonin treatment on the lodgement of circulating tumor cells. A vital fluorescence microscopic, electron microscopic and isotope study in the rat. ( Bagge, U; Ericson, LE; Skolnik, G, 1983)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Skolnik, G2
Ivarsson, L1
Bagge, U2
Ericson, LE1
Stücker, O1
Laemmel, E1
Teisseire, B1
Vicaut, E1
Manda, T1
Nishigaki, F1
Mori, J1
Shimomura, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Investigation of the Effect of Types of Catheters on Bloodstream Infection in Patients With Major Burns: Prediction With Procalcitonin and Prognosis[NCT05581316]34 participants (Actual)Interventional2019-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for ketanserin and Fibrosarcoma

ArticleYear
The influence of antiserotonin treatment with ketanserin on the pulmonary lodgement of circulating tumour cells in normal and traumatized rats.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Animals; Femoral Fractures; Fibrosarcoma; Ketanserin; Lung Neoplasms; Neoplasm Transplantation; Neop

1983
The effect of thrombocytopenia and antiserotonin treatment on the lodgement of circulating tumor cells. A vital fluorescence microscopic, electron microscopic and isotope study in the rat.
    Journal of cancer research and clinical oncology, 1983, Volume: 105, Issue:1

    Topics: Animals; Female; Fibrosarcoma; Ketanserin; Liver Neoplasms; Male; Microscopy, Electron; Microscopy,

1983
Specific response of mouse tumor-feeding arterioles to stimulation by 5-HT1 agonists.
    International journal of radiation oncology, biology, physics, 1997, Mar-15, Volume: 37, Issue:5

    Topics: Acetylcholine; Animals; Arterioles; Carcinogens; Female; Fibrosarcoma; Ketanserin; Methylcholanthren

1997
Important role of serotonin in the antitumor effects of recombinant human tumor necrosis factor-alpha in mice.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Animals; Cell Survival; Cyproheptadine; Female; Fibrosarcoma; Ketanserin; Mice; Mice, Inbred BALB C;

1988