ketanserin has been researched along with Edema in 5 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Local delivery of serotonin (5-HT) produces a rapid edematous response in soft tissues via increased fluid extravasation which is prevented by 5-HT2 antagonists such as ketanserin or mianserin." | 3.69 | A novel class of 5-HT2A receptor antagonists: aryl aminoguanidines. ( Baez, MB; Bryant, HU; Button, D; Cole, HW; Koppel, GA; Lucaites, VL; Nelson, DL; Reel, J; Simon, R; Wainscott, DB; Whitesitt, C, 1996) |
| " The 5-HT2 receptor-antagonistic properties of AHR-16303B were demonstrated by inhibition of (a) [3H]ketanserin binding to rat cerebral cortical membranes (IC50 = 165 nM); (b) 5-hydroxytryptamine (5-HT)-induced foot edema in rats (minimum effective dose, (MED) = 0." | 3.68 | AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels. ( Appell, KC; Barrett, RJ; Kilpatrick, BF; Nolan, JC; Proakis, AG; Walsh, DA, 1991) |
| "Edema was assessed by FITC-albumin extravasation." | 1.42 | 5-HT2a receptor antagonism reduces burn-induced macromolecular efflux in rats. ( Hernekamp, JF; Klein, H; Kneser, U; Kremer, T; Schmidt, K, 2015) |
| " dosage again displayed significant efficacy when administered at 15 min delaying treatment to 30 min resulted in only marginal therapeutic actions." | 1.29 | Characterization of mianserin neuroprotection in experimental spinal trauma: dose/route response and late treatment. ( Agresta, CA; Azim, S; Chavin, J; Kelly, G; Puniak, MA; Salzman, SK; Wang, L, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bryant, HU | 1 |
| Nelson, DL | 1 |
| Button, D | 1 |
| Cole, HW | 1 |
| Baez, MB | 1 |
| Lucaites, VL | 1 |
| Wainscott, DB | 1 |
| Whitesitt, C | 1 |
| Reel, J | 1 |
| Simon, R | 1 |
| Koppel, GA | 1 |
| Hernekamp, JF | 1 |
| Klein, H | 1 |
| Schmidt, K | 1 |
| Kneser, U | 1 |
| Kremer, T | 1 |
| Salzman, SK | 1 |
| Kelly, G | 1 |
| Chavin, J | 1 |
| Wang, L | 1 |
| Puniak, MA | 1 |
| Agresta, CA | 1 |
| Azim, S | 1 |
| Doak, GJ | 1 |
| Sawynok, J | 1 |
| Barrett, RJ | 1 |
| Appell, KC | 1 |
| Kilpatrick, BF | 1 |
| Proakis, AG | 1 |
| Nolan, JC | 1 |
| Walsh, DA | 1 |
5 other studies available for ketanserin and Edema
| Article | Year |
|---|---|
A novel class of 5-HT2A receptor antagonists: aryl aminoguanidines.
Topics: Animals; Cell Line, Transformed; Cell Membrane; Cricetinae; Edema; Female; Guanidines; Humans; Mesoc | 1996 |
5-HT2a receptor antagonism reduces burn-induced macromolecular efflux in rats.
Topics: Animals; Burns; Edema; Endothelium, Vascular; Hemodynamics; Ketanserin; Leukocytes; Mesentery; Rats, | 2015 |
Characterization of mianserin neuroprotection in experimental spinal trauma: dose/route response and late treatment.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Ketanserin; Male; Mian | 1994 |
Formalin-induced nociceptive behavior and edema: involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes.
Topics: Animals; Edema; Formaldehyde; Indoles; Inflammation; Ketanserin; Male; Pain; Propranolol; Rats; Rats | 1997 |
AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels.
Topics: Animals; Atrial Function; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Calci | 1991 |