ketanserin has been researched along with Diabetic Neuropathies in 3 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The streptozotocin-induced diabetic rat model was used to compare the efficacy of duloxetine, 5-HT, the 5-HT(2A) receptor agonist [1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)] and two antagonists (ketanserin and pruvanserin) on tactile allodynia." | 3.77 | A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. ( Jolivalt, CG; Mixcoatl-Zecuatl, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bektas, N | 1 |
| Arslan, R | 1 |
| Ozturk, Y | 1 |
| Mixcoatl-Zecuatl, T | 1 |
| Jolivalt, CG | 1 |
| Takeshita, N | 1 |
| Ohkubo, Y | 1 |
| Yamaguchi, I | 1 |
3 other studies available for ketanserin and Diabetic Neuropathies
| Article | Year |
|---|---|
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Disease Models, Animal; Dose-Respons | 2014 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochlor | 2011 |
Tiapride attenuates pain transmission through an indirect activation of central serotonergic mechanism.
Topics: Animals; Central Nervous System; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dopamine An | 1995 |