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ketanserin and Diabetes Mellitus, Type 2

ketanserin has been researched along with Diabetes Mellitus, Type 2 in 8 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to determine the efficacy of topically applied ketanserin for healing acceleration of diabetic foot ulcers."9.08Randomized single-blind trial of topical ketanserin for healing acceleration of diabetic foot ulcers. ( Castañeda, M; García-Alonso, J; Martínez-de Jesús, FR; Mendiola-Segura, I; Morales-Guzmán, M; Pérez-Morales, A, 1997)
"The objective of this study was to determine the efficacy of topically applied ketanserin for healing acceleration of diabetic foot ulcers."5.08Randomized single-blind trial of topical ketanserin for healing acceleration of diabetic foot ulcers. ( Castañeda, M; García-Alonso, J; Martínez-de Jesús, FR; Mendiola-Segura, I; Morales-Guzmán, M; Pérez-Morales, A, 1997)
"Ketanserin was well tolerated."2.66An evaluation of ketanserin therapy for the hypertensive diabetic patient. ( Tooke, JE; Williams, SA, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's6 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pietraszek, MH2
Takada, Y2
Taminato, A2
Yoshimi, T2
Watanabe, I2
Takada, A2
Takeshita, N1
Yamaguchi, I1
Martínez-de Jesús, FR1
Morales-Guzmán, M1
Castañeda, M1
Pérez-Morales, A1
García-Alonso, J1
Mendiola-Segura, I1
Fujita, M1
Carleo, R1
Gobbo, M1
Bonavita, M1
De Matteo, A1
Gallo, M1
Gatti, A1
Fogari, R1
Zoppi, A1
Pasotti, C1
Nicrosini, S1
Lazzari, P1
Corradi, L1
Tooke, JE1
Williams, SA1
Janka, HU1
Mehnert, H1
Fisher, R1
Seiler, KU1

Trials

2 trials available for ketanserin and Diabetes Mellitus, Type 2

ArticleYear
Randomized single-blind trial of topical ketanserin for healing acceleration of diabetic foot ulcers.
    Archives of medical research, 1997,Spring, Volume: 28, Issue:1

    Topics: Administration, Topical; Aged; Combined Modality Therapy; Debridement; Diabetes Mellitus, Type 2; Di

1997
An evaluation of ketanserin therapy for the hypertensive diabetic patient.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Blood Flow Velocity; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Bl

1989

Other Studies

6 other studies available for ketanserin and Diabetes Mellitus, Type 2

ArticleYear
The effect of MCI-9042 on serotonin-induced platelet aggregation in type 2 diabetes mellitus.
    Thrombosis research, 1993, Apr-15, Volume: 70, Issue:2

    Topics: Adult; Aged; Collagen; Diabetes Mellitus, Type 2; Female; Humans; Ketanserin; Male; Middle Aged; Pla

1993
Meta-chlorophenylpiperazine attenuates formalin-induced nociceptive responses through 5-HT1/2 receptors in both normal and diabetic mice.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Formaldehyde; Indoles; Ketanser

1995
Blood serotonergic mechanisms in type 2 (non-insulin-dependent) diabetes mellitus.
    Thrombosis research, 1992, Jun-15, Volume: 66, Issue:6

    Topics: Adult; Aged; Binding Sites; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabe

1992
[Effects of ketanserin on glucose metabolism in hypertensive diabetic subjects].
    Bollettino della Societa italiana di biologia sperimentale, 1990, Volume: 66, Issue:7

    Topics: Diabetes Mellitus, Type 2; Electrolytes; Female; Glucose; Hemodynamics; Humans; Hypertension; Insuli

1990
Ketanserin in chronic treatment of hypertension in type 2 diabetes mellitus.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:5

    Topics: Aged; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose; Glucose Tol

1990
Influence of ketanserin on glucose and lipid metabolism in diabetic patients with hypertension.
    Drugs, 1988, Volume: 36 Suppl 1

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Ketanserin; Lipids; M

1988