ketanserin has been researched along with Decerebrate Posturing in 17 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketanserin was found to attenuate the excitatory responses produced by norepinephrine, an alpha 1-adrenoceptor-mediated response, in the lateral geniculate nucleus." | 1.27 | Effects of ketanserin on neuronal responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus. ( Aghajanian, GK; Lakoski, JM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, M | 1 |
| Nishida, T | 1 |
| Ono, H | 1 |
| Koshizaki, M | 1 |
| Kawamata, M | 1 |
| Shimada, SG | 1 |
| Saito, Y | 1 |
| Collins, JG | 1 |
| Centurión, D | 1 |
| Mehotra, S | 1 |
| Sánchez-López, A | 1 |
| Gupta, S | 1 |
| MaassenVanDenBrink, A | 1 |
| Villalón, CM | 1 |
| Toppin, VA | 1 |
| Harris, MB | 1 |
| Kober, AM | 1 |
| Leiter, JC | 2 |
| St-John, WM | 2 |
| Zuperku, EJ | 1 |
| Brandes, IF | 1 |
| Stucke, AG | 1 |
| Sanchez, A | 1 |
| Hopp, FA | 1 |
| Stuth, EA | 1 |
| Castillo, C | 1 |
| Bobadilla, RA | 1 |
| Ibarra, M | 1 |
| Castillo, EF | 1 |
| Hong, E | 1 |
| Lee, JY | 1 |
| Hancock, AA | 1 |
| Warner, RB | 1 |
| Brune, ME | 1 |
| Meyer, MD | 1 |
| DeBernardis, JF | 1 |
| Bernardi, M | 1 |
| Rossini, L | 1 |
| Tonnini, C | 1 |
| Scalbert, E | 2 |
| Richer, C | 2 |
| Giudicelli, JF | 2 |
| Malinowska, B | 1 |
| Buczko, W | 1 |
| Aono, J | 1 |
| Nabata, H | 1 |
| Ishizuka, N | 1 |
| Sakai, K | 1 |
| Korstanje, C | 1 |
| Sprenkels, R | 1 |
| Doods, HN | 1 |
| Hugtenburg, JG | 1 |
| Boddeke, E | 1 |
| Batink, HD | 1 |
| Thoolen, MJ | 1 |
| Van Zwieten, PA | 1 |
| Gradin, K | 1 |
| Pettersson, A | 1 |
| Hedner, T | 1 |
| Persson, B | 1 |
| Göthert, M | 1 |
| Schlicker, E | 1 |
| Kollecker, P | 1 |
| Lakoski, JM | 1 |
| Aghajanian, GK | 1 |
17 other studies available for ketanserin and Decerebrate Posturing
| Article | Year |
|---|---|
Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cyproheptadine; Decerebrate State; Dose-Re | 2003 |
5-HT3 receptors partially mediate halothane depression of spinal dorsal horn sensory neurons.
Topics: Anesthetics, Inhalation; Animals; Decerebrate State; Depression, Chemical; Halothane; Indoles; Ketan | 2003 |
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Rec | 2006 |
Persistence of eupnea and gasping following blockade of both serotonin type 1 and 2 receptors in the in situ juvenile rat preparation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Decerebrate State; Disease Models, Animal; Dose-Res | 2007 |
Major components of endogenous neurotransmission underlying the discharge activity of hypoglossal motoneurons in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Decerebrate State; Dogs; Excitatory Amino Acid An | 2008 |
Maintenance of gasping and restoration of eupnea after hypoxia is impaired following blockers of alpha1-adrenergic receptors and serotonin 5-HT2 receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Am | 2008 |
A comparative study of the effects of some 5-HT1A receptor agonists on the blood pressure of pithed rats.
Topics: 5-Methoxytryptamine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; | 1995 |
Cardiovascular activity of A-74283, a 5-hydroxytryptamine 1A agent, in the spontaneously hypertensive rat.
Topics: Adrenergic Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cisterna Magna; Decerebrat | 1998 |
[Power spectra of the inter-cycle heart fluctuations in Xenopus laevis (L.), conscious or pithed, exposed to temperature changes and pharmacological treatments].
Topics: Adrenergic beta-Agonists; Animals; Body Temperature; Consciousness; Decerebrate State; Heart Conduct | 1991 |
Ketanserin: systemic and regional hemodynamic characterization of its serotonergic and alpha-adrenergic receptor blocking effects in the pithed SHR.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Cardiac Output | 1989 |
Influence of captopril on the vasopressor effect of serotonin in pithed rats.
Topics: Animals; Arteries; Blood Pressure; Captopril; Decerebrate State; Dose-Response Relationship, Drug; K | 1989 |
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Decerebrate State; Gastr | 1985 |
Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Decerebrate Stat | 1986 |
Chronic 5-HT2 receptor blockade with ritanserin does not reduce blood pressure in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; | 1985 |
Receptor-mediated effects of serotonin and 5-methoxytryptamine on noradrenaline release in the rat vena cava and in the heart of the pithed rat.
Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Decerebrate State; Desipramine; Electric Stimulation; | 1986 |
Effects of ketanserin on neuronal responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus.
Topics: Animals; Decerebrate State; Electrophysiology; Frontal Lobe; gamma-Aminobutyric Acid; Geniculate Bod | 1985 |
Lack of presynaptic effects of ketanserin on cardiac noradrenergic nerve terminals in the SHR.
Topics: Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Heart; Heart Rate; Ket | 1988 |