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ketanserin and Coronary Thrombosis

ketanserin has been researched along with Coronary Thrombosis in 6 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Accordingly, coronary thrombosis was induced in anesthetized, open-chest dogs by insertion of a copper coil into the left anterior descending coronary artery (LAD)."5.27Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis. ( Ashton, JH; Buja, LM; Glas-Greenwalt, P; Golino, P; McNatt, J; Willerson, JT, 1988)
"Accordingly, coronary thrombosis was induced in anesthetized, open-chest dogs by insertion of a copper coil into the left anterior descending coronary artery (LAD)."1.27Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis. ( Ashton, JH; Buja, LM; Glas-Greenwalt, P; Golino, P; McNatt, J; Willerson, JT, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kirchengast, M1
Rübsamen, K1
Lehmann, HD1
Vandeplassche, G1
Hermans, C1
Van Dael, L1
Wouters, L1
De Clerck, F1
Noble, MI2
Drake-Holland, AJ2
Dietrich, WD1
Busto, R1
Ginsberg, MD1
Golino, P1
Ashton, JH1
Glas-Greenwalt, P1
McNatt, J1
Buja, LM1
Willerson, JT1

Reviews

1 review available for ketanserin and Coronary Thrombosis

ArticleYear
The possible role of serotonin 5HT2 receptor antagonism in cardioprotection.
    The Netherlands journal of medicine, 1992, Volume: 41, Issue:3-4

    Topics: Arrhythmias, Cardiac; Blood Vessels; Coronary Thrombosis; Endothelium, Vascular; Humans; Ketanserin;

1992

Other Studies

5 other studies available for ketanserin and Coronary Thrombosis

ArticleYear
Inhibition by the combined Ca2+ and 5-HT2 receptor antagonist nexopamil (LU 49938) of intracoronary thrombus formation in a canine model of arterial stenosis and intimal damage.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5

    Topics: Animals; Calcium; Coronary Circulation; Coronary Thrombosis; Dogs; Female; Gallopamil; Hemodynamics;

1993
Interplay between platelet-derived 5-hydroxytryptamine and arachidonic acid metabolites limits the thrombolytic efficacy of streptokinase against canine platelet-rich coronary thrombosis.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1

    Topics: Animals; Arachidonic Acid; Bleeding Time; Blood Coagulation; Blood Platelets; Coronary Circulation;

1993
Evidence for a role of serotonin in initiation of coronary arterial thrombosis in dog and man.
    Clinical physiology and biochemistry, 1990, Volume: 8 Suppl 3

    Topics: Animals; Coronary Thrombosis; Dogs; Humans; Ketanserin; Platelet Aggregation; Receptors, Adrenergic,

1990
Effect of the serotonin antagonist ketanserin on the hemodynamic and morphological consequences of thrombotic infarction.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:6

    Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebral Infarction; Cerebrovascular Cir

1989
Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis.
    Circulation, 1988, Volume: 77, Issue:3

    Topics: Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Coronary Circulation; Coronary Di

1988