ketanserin has been researched along with Cold Fingers, Hereditary in 42 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This specific type of pharmaceutical treatment appeared to be especially suitable for this disease owing to a combination of therapeutic efficacy and a substantial reduction in the total dosage for each patient." | 2.67 | Regional intravenous ketanserin and guanethidine therapy in Raynaud's phenomenon. ( Caputi, CA; De Carolis, G; Tomasetti, C, 1991) |
| "The ketanserin treated group reported a 16." | 2.67 | Ketanserin and capillary flow in Raynaud's phenomenon. ( Black, C; Rawlinson, DW; Tooke, JE; Williams, SA, 1990) |
| "On Ketanserin treatment DBP measurements show a significant increase in the digit to brachial systolic blood pressure index (DBI) after cold provocation." | 2.66 | Quantitative study of the effects of Ketanserin in patients with primary Raynaud's phenomenon. A randomized, double blind, placebo controlled investigation and an additional long term open trial. ( Skotnicki, SH; van de Wal, HJ; van Lier, HJ; Wijn, PF, 1985) |
| "Ketanserin treatment was discontinued in one patient owing to dizziness and anxiety." | 2.66 | Effect of ketanserin on Raynaud's phenomenon in progressive systemic sclerosis: a double-blind trial. ( Lukác, J; Rovenský, J; Tauchmannová, H; Zitnan, D, 1985) |
| "Now progressive systemic sclerosis (PSS) is considered a disease of small vessels with which many immunologic alterations are associated." | 1.27 | Ketanserin in the treatment of progressive systemic sclerosis. ( Altomare, GF; Pigatto, PD; Polenghi, MM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (73.81) | 18.7374 |
| 1990's | 10 (23.81) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seibold, JR | 2 |
| Jageneau, AH | 1 |
| Roald, OK | 2 |
| Seem, E | 1 |
| Stranden, E | 1 |
| Krohg, K | 1 |
| Wollersheim, H | 1 |
| van Zwieten, PA | 1 |
| Gasser, P | 1 |
| Pola, P | 1 |
| Tondi, P | 1 |
| Serricchio, M | 1 |
| Favuzzi, A | 1 |
| Gerardino, L | 1 |
| Pope, J | 1 |
| Fenlon, D | 1 |
| Thompson, A | 1 |
| Shea, B | 1 |
| Furst, D | 1 |
| Wells, G | 1 |
| Silman, A | 1 |
| Brouwer, RM | 4 |
| Wenting, GJ | 4 |
| Schalekamp, MA | 4 |
| Coffman, JD | 2 |
| Arosio, E | 2 |
| Montesi, G | 2 |
| Zannoni, M | 2 |
| Perbellini, L | 2 |
| Paluani, F | 2 |
| Lechi, A | 2 |
| Caputi, CA | 1 |
| De Carolis, G | 1 |
| Tomasetti, C | 1 |
| Marasini, B | 3 |
| Biondi, ML | 2 |
| Mollica, R | 1 |
| Bassani, C | 1 |
| Tooke, JE | 1 |
| Williams, SA | 1 |
| Rawlinson, DW | 1 |
| Black, C | 1 |
| Longstaff, J | 1 |
| Gush, R | 1 |
| Williams, EH | 1 |
| Jayson, MI | 1 |
| Man in't Veld, AJ | 2 |
| Rustin, MH | 1 |
| Bunker, CB | 1 |
| Dowd, PM | 1 |
| Codella, O | 1 |
| Caramaschi, P | 1 |
| Olivieri, O | 1 |
| Perbellini, A | 1 |
| Bambara, LM | 1 |
| Corrocher, R | 1 |
| De Sandre, G | 1 |
| Clement, DL | 1 |
| Creager, MA | 1 |
| Dormandy, JA | 2 |
| Janssens, MM | 1 |
| McKendry, RJ | 1 |
| Murray, GD | 1 |
| Nielsen, SL | 1 |
| Belch, JJ | 1 |
| vd Meiracker, AJ | 1 |
| Kunnen, JJ | 1 |
| Dahler, HP | 1 |
| Doorenspleet, JG | 1 |
| van Oene, JC | 2 |
| Lazareth, I | 1 |
| Allegra, C | 1 |
| Tonelli, V | 1 |
| Bonifacio, M | 1 |
| Mari, A | 1 |
| Assogna, G | 1 |
| Terregino, CA | 1 |
| van de Wal, HJ | 1 |
| Wijn, PF | 1 |
| van Lier, HJ | 1 |
| Skotnicki, SH | 1 |
| Lagerkvist, BE | 1 |
| Linderholm, H | 1 |
| Engelhart, M | 1 |
| Berent, A | 1 |
| Downes, SJ | 1 |
| Larsen, VH | 1 |
| Fabricius, J | 1 |
| Nielsen, G | 1 |
| Hansen, KS | 1 |
| Burns, EC | 1 |
| Dunger, DB | 1 |
| Dillon, MJ | 1 |
| Bianchi, E | 1 |
| Dell'Orto, P | 1 |
| Agostoni, A | 1 |
| Bellucci, S | 1 |
| Kedra, W | 1 |
| Ajzenberg, N | 1 |
| Tobelem, G | 1 |
| Caen, J | 1 |
| Visser, W | 1 |
| Altomare, GF | 1 |
| Pigatto, PD | 1 |
| Polenghi, MM | 1 |
| Cadranel, J | 1 |
| Blétry, O | 1 |
| Guillevin, L | 1 |
| Lacombe, C | 1 |
| Fraitag, B | 1 |
| Duloroy, J | 1 |
| Mouthon, JM | 1 |
| Godeau, P | 1 |
| Baart de la Faille, H | 1 |
| van Weelden, H | 1 |
| Banga, JD | 1 |
| van Kesteren, RG | 1 |
| Kirch, W | 1 |
| Linder, HR | 1 |
| Hutt, HJ | 1 |
| Ohnhaus, EE | 1 |
| Mahler, F | 1 |
| Meloni, F | 1 |
| Transi, MG | 1 |
| Sciacca, V | 1 |
| De Felice, C | 1 |
| Bagarone, A | 1 |
| Sciacca, A | 1 |
| Lukác, J | 1 |
| Rovenský, J | 1 |
| Tauchmannová, H | 1 |
| Zitnan, D | 1 |
4 reviews available for ketanserin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis.
Topics: Humans; Ketanserin; Raynaud Disease; Scleroderma, Systemic; Serotonin Antagonists | 2000 |
Raynaud's phenomenon. An update.
Topics: Calcium Channel Blockers; Captopril; Humans; Ketanserin; Prostaglandins; Raynaud Disease; Sympatholy | 1991 |
Raynaud's phenomenon.
Topics: Antibody Formation; Blood Vessels; Endothelium, Vascular; Fatty Acids, Essential; Humans; Inflammati | 1989 |
[New treatments for Raynaud's syndrome].
Topics: Alprostadil; Epoprostenol; Humans; Ketanserin; Raynaud Disease; Receptors, Serotonin | 1988 |
24 trials available for ketanserin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Treatment of Raynaud's phenomenon with ketanserin, a selective antagonist of the serotonin2 (5-HT2) receptor.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Fingers; Humans; Ketanserin; Male; Middle Aged; Pilot | 1984 |
Treatment of Raynaud's phenomenon with ketanserin in patients with connective tissue disorders.
Topics: Adult; Clinical Trials as Topic; Connective Tissue Diseases; Double-Blind Method; Female; Fingers; H | 1984 |
Treatment of Raynaud's phenomenon with the 5-HT2-receptor antagonist ketanserin.
Topics: Adult; Aged; Female; Fingers; Humans; Ketanserin; Male; Middle Aged; Piperidines; Raynaud Disease; R | 1982 |
New prospects for the treatment of Raynaud's phenomenon using a serotoninergic S2 receptor antagonist (ketanserin) and stable derivatives of prostacyclin.
Topics: Adult; Aged; Blood Gas Monitoring, Transcutaneous; Drug Therapy, Combination; Epoprostenol; Female; | 1993 |
Regional intravenous ketanserin and guanethidine therapy in Raynaud's phenomenon.
Topics: Adult; Evaluation Studies as Topic; Female; Guanethidine; Humans; Injections, Intravenous; Ketanseri | 1991 |
Ketanserin and capillary flow in Raynaud's phenomenon.
Topics: Adult; Blood Flow Velocity; Capillaries; Cold Temperature; Female; Fingers; Humans; Ketanserin; Male | 1990 |
Effects of ketanserin on peripheral blood flow, haemorheology, and platelet function in patients with Raynaud's phenomenon.
Topics: Adult; Aged; Blood Platelets; Blood Viscosity; Female; Fingers; Humans; Ketanserin; Male; Middle Age | 1985 |
Role of alpha-adrenergic blockade in the cardiovascular actions of ketanserin: studies in patients with essential hypertension, autonomic insufficiency, and Raynaud's phenomenon.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Humans | 1987 |
Controlled comparison of ketanserin and nifedipine in Raynaud's phenomenon.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Ketanserin; Male; Middle Aged; Nifedipine; Ra | 1989 |
Comparative efficacy of ketanserin and pentoxiphylline in treatment of Raynaud's phenomenon.
Topics: Adult; Clinical Trials as Topic; Female; Hand; Humans; Ketanserin; Male; Middle Aged; Pentoxifylline | 1989 |
International study of ketanserin in Raynaud's phenomenon.
Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Fingers; Humans; Ketanserin; | 1989 |
Effects of intra-arterial ketanserin in Raynaud's phenomenon assessed by 99MTc-pertechnetate scintigraphy.
Topics: Adult; Aged; Aged, 80 and over; Female; Hand; Humans; Injections, Intra-Arterial; Ketanserin; Male; | 1988 |
Raynaud's disease: a new therapeutic approach with a 5-HT2 receptors blocker.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketanserin; | 1985 |
Selective antagonism of S2-serotonergic receptors relieves but does not prevent cold induced vasoconstriction in primary Raynaud's phenomenon.
Topics: Adult; Cold Temperature; Female; Humans; Ketanserin; Piperidines; Raynaud Disease; Receptors, Adrene | 1986 |
Quantitative study of the effects of Ketanserin in patients with primary Raynaud's phenomenon. A randomized, double blind, placebo controlled investigation and an additional long term open trial.
Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Blood Pressure; Clinical Trials as Topic; Double-Blind | 1985 |
Ketanserin in the treatment of Raynaud's phenomenon associated with generalized scleroderma.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketanserin; Male; Middle | 1988 |
The use of the selective serotonin S2 receptor antagonist Ketanserin in the treatment of Raynaud's phenomenon.
Topics: Adult; Aged; Blood Flow Velocity; Clinical Trials as Topic; Double-Blind Method; Female; Fingers; Hu | 1988 |
Ketanserin in the treatment of traumatic vasospastic disease.
Topics: Adult; Blood Pressure; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Fingers; Hum | 1986 |
Ketanserin treatment and serotonin in patients with primary and secondary Raynaud's phenomenon.
Topics: Adolescent; Adult; Blood Platelets; Double-Blind Method; Female; Humans; Ketanserin; Male; Middle Ag | 1988 |
Does serotonin receptor blockade have a therapeutic effect in Raynaud's phenomenon?
Topics: Adult; Clinical Trials as Topic; Female; Fingers; Humans; Ketanserin; Male; Middle Aged; Raynaud Dis | 1987 |
[Treatment of systemic scleroderma with ketanserin. Randomized, double-blind 6-months study of 27 cases].
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketanserin; Male; Random Allocation; | 1986 |
Cold-induced Raynaud's phenomenon ameliorated by intravenous administration of ketanserin: a double-blind cross-over study.
Topics: Adult; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Female; Humans; Infusions, I | 1986 |
Ketanserin versus nifedipine in secondary Raynaud's phenomenon.
Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Humans; Ketanserin; Male; Middle Aged; Nifedipi | 1987 |
Effect of ketanserin on Raynaud's phenomenon in progressive systemic sclerosis: a double-blind trial.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Fingers; Humans; Ketanserin; Male; Mid | 1985 |
14 other studies available for ketanserin and Cold Fingers, Hereditary
| Article | Year |
|---|---|
Treatment of Raynaud's phenomenon.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Electric Stimulation Therapy; Humans; Ketans | 1993 |
[The use of capillary videomicroscopy in the therapeutic assessment of acral vasospastic phenomena: microcirculatory effect of ketanserin and nifedipine].
Topics: Capillaries; Humans; Ketanserin; Microcirculation; Microscopy; Nifedipine; Raynaud Disease; Video Re | 1994 |
Acute effects and mechanism of action of ketanserin in patients with primary Raynaud's phenomenon.
Topics: Adult; Blood Gas Monitoring, Transcutaneous; Female; Fingers; Humans; Ketanserin; Lasers; Male; Oxyg | 1990 |
Efficacy of ketanserin in the therapy of Raynaud's phenomenon: thermometric data.
Topics: Adult; Female; Fingers; Humans; Ketanserin; Male; Raynaud Disease; Skin Temperature; Thermometers | 1991 |
Effect of chronic ketanserin treatment on serotonin-induced platelet aggregation in patients with Raynaud's phenomenon.
Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Ketanserin; Middle Aged; Platelet Aggregati | 1990 |
Digital blood flow and 5-hydroxytryptamine receptor blockade after ketanserin in patients with Raynaud's phenomenon.
Topics: Adult; Blood Flow Velocity; Female; Fingers; Humans; Ketanserin; Male; Middle Aged; Platelet Aggrega | 1990 |
Chronic leg ulceration with livedoid vasculitis, and response to oral ketanserin.
Topics: Administration, Oral; Chronic Disease; Female; Humans; Ketanserin; Leg Ulcer; Middle Aged; Raynaud D | 1989 |
Mechanism of action of ketanserin in hypertension and vasospastic disease.
Topics: Blood Pressure; Drug Therapy, Combination; Fingers; Humans; Hypertension; Ketanserin; Muscle, Smooth | 1987 |
[Treatment of Raynaud's phenomenon].
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Captopril; Humans; Ketanserin; Prostaglandin | 1987 |
Cold hands after exposure to arsenic or vibrating tools: effects of ketanserin on finger blood pressure and skin temperature.
Topics: Administration, Oral; Adult; Arsenic Poisoning; Blood Pressure; Double-Blind Method; Hand; Humans; I | 1986 |
Raynaud's disease.
Topics: Antihypertensive Agents; Child; Dinoprostone; Epoprostenol; Female; Humans; Ketanserin; Male; Nifedi | 1985 |
Hypertensive patients with Raynaud's phenomenon or intermittent claudication and their treatment with ketanserin.
Topics: Humans; Hypertension; Intermittent Claudication; Ketanserin; Raynaud Disease | 1988 |
Ketanserin in the treatment of progressive systemic sclerosis.
Topics: Adult; Female; Fingers; Humans; Ketanserin; Middle Aged; Raynaud Disease; Regional Blood Flow; Scler | 1988 |
Therapeutic efficacy of ketanserin, a selective antagonist of the serotonin (5-HT2) receptors, in primary and secondary Raynaud's phenomenon.
Topics: Adult; Aged; Female; Humans; Ketanserin; Male; Microcirculation; Middle Aged; Raynaud Disease; Recep | 1987 |