Page last updated: 2024-10-29

ketanserin and Cirrhosis

ketanserin has been researched along with Cirrhosis in 3 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Biliary fibrosis is a major complication after donation after cardiac death (DCD) liver transplantation."5.40Ketanserin, a serotonin 2A receptor antagonist, alleviates ischemia-related biliary fibrosis following donation after cardiac death liver transplantation in rats. ( Chen, G; Chen, L; Fan, W; Guo, Y; Liu, L; Qian, Y; Shi, B; Xiao, L, 2014)
"Biliary fibrosis is a major complication after donation after cardiac death (DCD) liver transplantation."1.40Ketanserin, a serotonin 2A receptor antagonist, alleviates ischemia-related biliary fibrosis following donation after cardiac death liver transplantation in rats. ( Chen, G; Chen, L; Fan, W; Guo, Y; Liu, L; Qian, Y; Shi, B; Xiao, L, 2014)
" Chronic administration of these antagonists strongly prevented exacerbation of ventricular hypertrophy in MAO-A KO mice."1.35Genetic deletion of MAO-A promotes serotonin-dependent ventricular hypertrophy by pressure overload. ( Bianchi, P; Calise, D; Escourrou, G; Galinier, M; Guilbeau-Frugier, C; Lairez, O; Mialet-Perez, J; Ordener, C; Parini, A; Pizzinat, N; Roncalli, J; Seif, I; Spreux-Varoquaux, O, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, L1
Chen, G1
Guo, Y1
Liu, L1
Xiao, L1
Fan, W1
Shi, B1
Qian, Y1
Chen, C1
Han, X1
Fan, F1
Liu, Y1
Wang, T1
Wang, J1
Hu, P1
Ma, A1
Tian, H1
Lairez, O1
Calise, D1
Bianchi, P1
Ordener, C1
Spreux-Varoquaux, O1
Guilbeau-Frugier, C1
Escourrou, G1
Seif, I1
Roncalli, J1
Pizzinat, N1
Galinier, M1
Parini, A1
Mialet-Perez, J1

Other Studies

3 other studies available for ketanserin and Cirrhosis

ArticleYear
Ketanserin, a serotonin 2A receptor antagonist, alleviates ischemia-related biliary fibrosis following donation after cardiac death liver transplantation in rats.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2014, Volume: 20, Issue:11

    Topics: Animals; Biliary Tract Diseases; Cells, Cultured; Drug Evaluation, Preclinical; Fibroblasts; Fibrosi

2014
Serotonin drives the activation of pulmonary artery adventitial fibroblasts and TGF-β1/Smad3-mediated fibrotic responses through 5-HT(2A) receptors.
    Molecular and cellular biochemistry, 2014, Volume: 397, Issue:1-2

    Topics: Adventitia; Animals; Cell Proliferation; Connective Tissue Growth Factor; Extracellular Matrix; Fibr

2014
Genetic deletion of MAO-A promotes serotonin-dependent ventricular hypertrophy by pressure overload.
    Journal of molecular and cellular cardiology, 2009, Volume: 46, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Fibrosis; Fluorobenzenes; Gene Deletion; Gene Expressi

2009