ketanserin has been researched along with Chronic Motor and Vocal Tic Disorder in 3 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty adults with Tourette's syndrome and 20 healthy control subjects were investigated with PET-[18F]altanserin using a bolus-infusion protocol." | 1.34 | Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome. ( Bolwig, TG; Hansen, ES; Haugbøl, S; Knudsen, GM; Nielsen, FA; Pinborg, LH; Regeur, L; Skovgaard, LT; Svarer, C, 2007) |
| " Initially, we established a dose-response relationship for the acute and chronic haloperidol and DOI-induced HTR." | 1.33 | Effects of donepezil, nicotine and haloperidol on the central serotonergic system in mice: implications for Tourette's syndrome. ( Hayslett, RL; Tizabi, Y, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayslett, RL | 1 |
| Tizabi, Y | 1 |
| Haugbøl, S | 1 |
| Pinborg, LH | 1 |
| Regeur, L | 1 |
| Hansen, ES | 1 |
| Bolwig, TG | 1 |
| Nielsen, FA | 1 |
| Svarer, C | 1 |
| Skovgaard, LT | 1 |
| Knudsen, GM | 1 |
| Bonnier, C | 1 |
| Nassogne, MC | 1 |
| Evrard, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open Label, Proof-of-Principle, Pilot Study to Evaluate Pimavanserin for the Treatment of Motor and Behavioral Symptoms of Tourette Syndrome[NCT04794413] | Early Phase 1 | 10 participants (Actual) | Interventional | 2018-11-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ketanserin and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Ketanserin treatment of Tourette's syndrome in children.
Topics: Adolescent; Age Factors; Child; Drug Administration Schedule; Female; Humans; Ketanserin; Male; Sero | 1999 |
2 other studies available for ketanserin and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Effects of donepezil, nicotine and haloperidol on the central serotonergic system in mice: implications for Tourette's syndrome.
Topics: Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Don | 2005 |
Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome.
Topics: Adolescent; Adult; Brain Chemistry; Female; Humans; Ketanserin; Magnetic Resonance Imaging; Male; Mi | 2007 |