Page last updated: 2024-10-29

ketanserin and Chronic Kidney Failure

ketanserin has been researched along with Chronic Kidney Failure in 8 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Ketanserin is an anti-hypertensive drug with an ability to reduce blood pressure variability (BPV) in acute experiments in spontaneously hypertensive rats (SHRs)."1.32Effects of long-term treatment with ketanserin on blood pressure variability and end-organ damage in spontaneously hypertensive rats. ( Du, WM; Liu, JG; Miao, CY; Shen, FM; Su, DF; Yang, XQ, 2003)
" In both dialysis and non-dialysis patients the terminal half-life of ketanserin (mean +/- s."1.28Ketanserin pharmacokinetics in patients with renal failure. ( Barendregt, JN; Tjandra, YI; Van Der Hoeven, JG; Van Oene, JC; Van Peer, A, 1990)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's5 (62.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, WM1
Miao, CY1
Liu, JG1
Shen, FM1
Yang, XQ1
Su, DF1
Borawski, J3
Mazerska, M3
Pawlak, K3
Myƛliwiec, M4
Azzadin, A1
Mysliwiec, J1
Wollny, T1
Buczko, W1
Barendregt, JN1
Van Peer, A1
Van Der Hoeven, JG1
Van Oene, JC1
Tjandra, YI1
Yamakado, M1
Nagano, M1
Umezu, M1
Tagawa, H1
Kiyose, H1
Zazgornik, J1
Scholz, N1
Kuska, J1
Minar, E1

Trials

1 trial available for ketanserin and Chronic Kidney Failure

ArticleYear
Ketanserin lowers erythropoietin concentration in hemodialyzed patients treated with the hormone.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Bleeding Time; Blood Platelets; Blood Pressure; Erythrocyte Co

1995

Other Studies

7 other studies available for ketanserin and Chronic Kidney Failure

ArticleYear
Effects of long-term treatment with ketanserin on blood pressure variability and end-organ damage in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:2

    Topics: Animals; Blood Pressure; Female; Hypertension; Hypertrophy, Left Ventricular; Ketanserin; Kidney Fai

2003
[Ketanserin decreases erythropoietin concentration in hemodialyzed patients on rHuEPO therapy].
    Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 92 Spec No

    Topics: Adolescent; Adult; Blood Pressure; Erythrocyte Count; Erythropoiesis; Erythropoietin; Female; Hemogl

1994
Serotonin is involved in the pathogenesis of hypertension developing during erythropoietin treatment in uremic rats.
    Thrombosis research, 1995, Feb-01, Volume: 77, Issue:3

    Topics: Anemia; Animals; Blood Platelets; Endothelium, Vascular; Erythropoietin; Hypertension; Ketanserin; K

1995
Ketanserin and erythropoiesis in hemodialysis patients with polycystic kidneys.
    American journal of nephrology, 1996, Volume: 16, Issue:5

    Topics: Adult; Erythrocyte Count; Erythropoiesis; Erythropoietin; Humans; Ketanserin; Kidney Failure, Chroni

1996
Ketanserin pharmacokinetics in patients with renal failure.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:6

    Topics: Adult; Aged; Blood Proteins; Female; Half-Life; Humans; Ketanserin; Kidney Failure, Chronic; Male; M

1990
Role of endogenous serotonin in the regulation of blood pressure in patients with chronic renal failure.
    Drugs, 1988, Volume: 36 Suppl 1

    Topics: Adult; Aged; Blood Pressure; Female; Humans; Ketanserin; Kidney Failure, Chronic; Male; Middle Aged;

1988
Plasma concentrations of ketanserin in chronic hemodialysed patients.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:12

    Topics: Adult; Blood Pressure; Humans; Hypertension; Ketanserin; Kidney Failure, Chronic; Kinetics; Middle A

1986