ketanserin has been researched along with Cerebral Ischemia in 9 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term effects of the 5-HT(2A) receptor antagonist ketanserin on deficits in sensorimotor integration (limb placing tests) following transient focal cerebral ischemia in rats were compared to the effects of the NMDA antagonist MK-801." | 7.74 | Endothelin-1-induced cerebral ischemia: effects of ketanserin and MK-801 on limb placing in rats. ( Kortenska, L; Mitreva, R; Moyanova, S, 2007) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated." | 7.68 | Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992) |
| "We examined whether ketanserin and mianserin, drugs with 5-HT2 receptor antagonistic effects, would have protective effects in Mongolian gerbils on delayed neuronal death induced by cerebral ischemia." | 7.68 | Effects of ketanserin and mianserin on delayed neuronal death induced by cerebral ischemia in Mongolian gerbils. ( Araki, H; Karasawa, Y; Otomo, S, 1992) |
| "The long-term effects of the 5-HT(2A) receptor antagonist ketanserin on deficits in sensorimotor integration (limb placing tests) following transient focal cerebral ischemia in rats were compared to the effects of the NMDA antagonist MK-801." | 3.74 | Endothelin-1-induced cerebral ischemia: effects of ketanserin and MK-801 on limb placing in rats. ( Kortenska, L; Mitreva, R; Moyanova, S, 2007) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated." | 3.68 | Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992) |
| "We examined whether ketanserin and mianserin, drugs with 5-HT2 receptor antagonistic effects, would have protective effects in Mongolian gerbils on delayed neuronal death induced by cerebral ischemia." | 3.68 | Effects of ketanserin and mianserin on delayed neuronal death induced by cerebral ischemia in Mongolian gerbils. ( Araki, H; Karasawa, Y; Otomo, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martín, A | 2 |
| Szczupak, B | 1 |
| Gómez-Vallejo, V | 1 |
| Plaza, S | 1 |
| Padró, D | 1 |
| Cano, A | 1 |
| Llop, J | 1 |
| Kang, TH | 1 |
| Murakami, Y | 1 |
| Takayama, H | 1 |
| Kitajima, M | 1 |
| Aimi, N | 1 |
| Watanabe, H | 1 |
| Matsumoto, K | 1 |
| Chang, CP | 1 |
| Chen, SH | 1 |
| Lin, MT | 1 |
| Moyanova, S | 1 |
| Kortenska, L | 1 |
| Mitreva, R | 1 |
| Kodama, K | 1 |
| Shibata, S | 1 |
| Ueki, S | 1 |
| Karasawa, Y | 1 |
| Araki, H | 1 |
| Otomo, S | 1 |
| Kagami, Y | 1 |
| Shigenobu, S | 1 |
| Watanabe, S | 1 |
| Kumami, K | 1 |
| Yamamoto, T | 1 |
| Villacara, A | 1 |
| Mrsulja, BB | 1 |
| Spatz, M | 1 |
| Brown, CM | 1 |
| Kilpatrick, AT | 1 |
| Spedding, M | 1 |
1 review available for ketanserin and Cerebral Ischemia
| Article | Year |
|---|---|
Ischemic cerebral edema. 5-Hydroxytryptamine receptors and the physical state of synaptosomal membranes.
Topics: Animals; Brain Edema; Brain Ischemia; Fluorescence Polarization; Gerbillinae; Ketanserin; Membrane F | 1990 |
8 other studies available for ketanserin and Cerebral Ischemia
| Article | Year |
|---|---|
PET imaging of serotoninergic neurotransmission with [(11)C]DASB and [(18)F]altanserin after focal cerebral ischemia in rats.
Topics: Animals; Benzylamines; Brain; Brain Ischemia; Carbon Radioisotopes; Contrast Media; Fluorine Radiois | 2013 |
Protective effect of rhynchophylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in the hippocampus: putative neurotransmitter receptors involved in their action.
Topics: Alkaloids; Animals; Brain Ischemia; Cell Hypoxia; Hippocampus; In Vitro Techniques; Indole Alkaloids | 2004 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Endothelin-1-induced cerebral ischemia: effects of ketanserin and MK-801 on limb placing in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Ischemia; Disease Models, Animal; Dizocilpine | 2007 |
Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia.
Topics: Acetylcholine; Animals; Brain Ischemia; Central Nervous System Stimulants; Deoxyglucose; Hippocampus | 1992 |
Effects of ketanserin and mianserin on delayed neuronal death induced by cerebral ischemia in Mongolian gerbils.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Ischemia; Cell Death; Gerbillinae; Hippocampu | 1992 |
Neuroprotective effect of 5-HT3 receptor antagonist on ischemia-induced decrease in CA1 field potential in rat hippocampal slices.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain Ischemia; Bridged Bicyclo Compounds; Bridged Bicyclo Compoun | 1992 |
Cerebral ischaemia reduces the density of 5-HT2 binding sites in the frontal cortex of the gerbil.
Topics: Animals; Binding, Competitive; Brain Ischemia; Cerebral Cortex; Female; Gerbillinae; In Vitro Techni | 1988 |