ketanserin has been researched along with Cardiovascular Pregnancy Complications in 8 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 9.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| "To establish the optimal dosage of ketanserin in the treatment of severe hypertension in pregnancy." | 9.10 | The optimal dosage of ketanserin for patients with severe hypertension in pregnancy. ( de Jeu, RM; Odendaal, HJ; Steyn, DW; van Geijn, HP; van Schie, DL, 2002) |
| "We found an association between the addition of ketanserin to aspirin and a decrease in the number of cases of pre-eclampsia and severe hypertension, as well as improved pregnancy outcome among patients with mild to moderate midtrimester hypertension." | 9.08 | Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997) |
| " The need for delivery for fetal distress did not differ (3 after dihydralazine, 1 after ketanserin, P = 0." | 9.08 | Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results. ( Odendaal, HJ; Steyn, DW, 1997) |
| "To compare the haemodynamic efficacy of ketanserin (a selective serotonin2-receptor blocker) with dihydralazine in the management of severe early-onset hypertension in pregnancy." | 9.08 | The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy. ( Bolte, AC; Dekker, GA; Strack van Schijndel, RJ; van Eyck, J; van Geijn, HP, 1998) |
| "After completion of this article, the reader will be able to list the various drugs and their associated side effects that are used to treat hypertensive disorders during pregnancy; to describe the various effects of serotonin on the cardiovascular system; to summarize the literature concerning the use of ketanserin during pregnancy; and to list the potential uses of ketanserin in this setting." | 8.80 | Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin. ( Odendaal, HJ; Steyn, DW, 2000) |
| "Determine the definitive position of ketanserin and dihydralazine for treatment of severe hypertension in pregnancy." | 5.20 | Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. ( Bijvank, SW; Duvekot, JJ; Edens, MA; Hanff, LM; Roofthooft, DW; Steegers, EA; Visser, W; Vulto, AG, 2015) |
| "To establish the optimal dosage of ketanserin in the treatment of severe hypertension in pregnancy." | 5.10 | The optimal dosage of ketanserin for patients with severe hypertension in pregnancy. ( de Jeu, RM; Odendaal, HJ; Steyn, DW; van Geijn, HP; van Schie, DL, 2002) |
| "We found an association between the addition of ketanserin to aspirin and a decrease in the number of cases of pre-eclampsia and severe hypertension, as well as improved pregnancy outcome among patients with mild to moderate midtrimester hypertension." | 5.08 | Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997) |
| " The need for delivery for fetal distress did not differ (3 after dihydralazine, 1 after ketanserin, P = 0." | 5.08 | Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results. ( Odendaal, HJ; Steyn, DW, 1997) |
| "To compare the haemodynamic efficacy of ketanserin (a selective serotonin2-receptor blocker) with dihydralazine in the management of severe early-onset hypertension in pregnancy." | 5.08 | The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy. ( Bolte, AC; Dekker, GA; Strack van Schijndel, RJ; van Eyck, J; van Geijn, HP, 1998) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "After completion of this article, the reader will be able to list the various drugs and their associated side effects that are used to treat hypertensive disorders during pregnancy; to describe the various effects of serotonin on the cardiovascular system; to summarize the literature concerning the use of ketanserin during pregnancy; and to list the potential uses of ketanserin in this setting." | 4.80 | Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin. ( Odendaal, HJ; Steyn, DW, 2000) |
| "The etiology of preeclampsia is still unknown." | 2.41 | Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers. ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Bijvank, SW | 1 |
| Visser, W | 1 |
| Duvekot, JJ | 1 |
| Steegers, EA | 1 |
| Edens, MA | 1 |
| Roofthooft, DW | 1 |
| Vulto, AG | 1 |
| Hanff, LM | 1 |
| Steyn, DW | 4 |
| Odendaal, HJ | 4 |
| Bolte, AC | 2 |
| van Eyck, J | 1 |
| Strack van Schijndel, RJ | 1 |
| van Geijn, HP | 3 |
| Dekker, GA | 2 |
| van Schie, DL | 1 |
| de Jeu, RM | 1 |
3 reviews available for ketanserin and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Ketanserin; | 2000 |
Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diureti | 2001 |
5 trials available for ketanserin and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Dihydralazine; Double-Blind Method; Female; Gestational Age; Hospita | 2015 |
Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Hum | 1997 |
Dihydralazine or ketanserin for severe hypertension in pregnancy? Preliminary results.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dihydralazine; Double-Blind Method; Female; Fetal De | 1997 |
The haemodynamic effects of ketanserin versus dihydralazine in severe early-onset hypertension in pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Dihydralazine; Female; Heart Rate; H | 1998 |
The optimal dosage of ketanserin for patients with severe hypertension in pregnancy.
Topics: Adult; Antihypertensive Agents; Cesarean Section; Double-Blind Method; Female; Humans; Hypertension; | 2002 |