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ketanserin and Bronchopulmonary Dysplasia

ketanserin has been researched along with Bronchopulmonary Dysplasia in 1 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.

Research Excerpts

ExcerptRelevanceReference
"Treatment with ketanserin attenuated bleomycin-induced PH (increased RVSP and RVH) and pulmonary vascular remodeling (decreased vessel density and increased muscularization of small vessels)."1.48Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice. ( Delaney, C; Fisher, S; Maltzahn, J; Nozik-Grayck, E; Sherlock, L; Wright, C, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delaney, C1
Sherlock, L1
Fisher, S1
Maltzahn, J1
Wright, C1
Nozik-Grayck, E1

Other Studies

1 other study available for ketanserin and Bronchopulmonary Dysplasia

ArticleYear
Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice.
    American journal of physiology. Lung cellular and molecular physiology, 2018, 05-01, Volume: 314, Issue:5

    Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Bleomycin; Bronchopulmonary Dysplasia; Hyper

2018