ketanserin has been researched along with Brain Edema in 4 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The alniditan response was blocked by the 5-HT(1B/D) receptor antagonist, GR 127935 (2'-methyl-4'-(5-methyl-[1,2, 4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide), but not by ketanserin, indicating that the effect is mediated through 5-HT(1B/D) receptors." | 1.30 | Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery. ( Bischoff, A; Diener, H; Fetscher, C; Limmroth, V; Michel, MC; Wermelskirchen, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, A | 1 |
| Castellani, RJ | 1 |
| Smith, MA | 1 |
| Muresanu, DF | 1 |
| Dey, PK | 1 |
| Sharma, HS | 1 |
| Limmroth, V | 1 |
| Bischoff, A | 1 |
| Fetscher, C | 1 |
| Wermelskirchen, D | 1 |
| Diener, H | 1 |
| Michel, MC | 1 |
| Kumami, K | 2 |
| Yamamoto, T | 1 |
| Villacara, A | 1 |
| Mrsulja, BB | 2 |
| Spatz, M | 2 |
| Wroblewska, B | 1 |
| Cvejic, V | 1 |
1 review available for ketanserin and Brain Edema
| Article | Year |
|---|---|
Ischemic cerebral edema. 5-Hydroxytryptamine receptors and the physical state of synaptosomal membranes.
Topics: Animals; Brain Edema; Brain Ischemia; Fluorescence Polarization; Gerbillinae; Ketanserin; Membrane F | 1990 |
3 other studies available for ketanserin and Brain Edema
| Article | Year |
|---|---|
5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology.
Topics: 5-Hydroxytryptophan; Albumins; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Brain Edema; C | 2019 |
Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery.
Topics: Animals; Basilar Artery; Benzopyrans; Brain Edema; Capillary Permeability; Dose-Response Relationshi | 1999 |
Cerebrocortical modulation of S2-receptors and turnover rate of 5-hydroxytryptamine in ischemia.
Topics: Animals; Brain Edema; Cerebral Cortex; Gerbillinae; Ischemic Attack, Transient; Ketanserin; Kinetics | 1987 |