ketanserin has been researched along with Asthma in 5 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied eight adult atopic asthmatic patients in a randomized double-blind, placebo-controlled, cross-over trial in order to examine the effects of the 5 HT2 antagonist ketanserin on airways function (FEV1, FVC, V50(chi), and V25(pi]." | 9.06 | The effects of the 5 HT2 antagonist ketanserin in adult atopic asthma. ( Ball, SG; Roberts, JA; Stott, DJ; Thomson, NC, 1988) |
| "We have studied eight adult atopic asthmatic patients in a randomized double-blind, placebo-controlled, cross-over trial in order to examine the effects of the 5 HT2 antagonist ketanserin on airways function (FEV1, FVC, V50(chi), and V25(pi]." | 5.06 | The effects of the 5 HT2 antagonist ketanserin in adult atopic asthma. ( Ball, SG; Roberts, JA; Stott, DJ; Thomson, NC, 1988) |
| "Seven young extrinsic asthmatics participated in an open, pilot study to determine the protective effect of a selective 5-hydroxytryptamine (5-HT) blocking agent, ketanserin, on exercise induced asthma." | 3.67 | Selective 5-HT2 receptor blockade in exercise-induced asthma. ( Kwan, S; Lam, WK; So, SY, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wohlsen, A | 1 |
| Uhlig, S | 1 |
| Martin, C | 1 |
| Ikawati, Z | 1 |
| Nose, M | 1 |
| Maeyama, K | 1 |
| Cazzola, M | 1 |
| Assogna, G | 1 |
| Lucchetti, G | 1 |
| Cicchitto, G | 1 |
| D'Amato, G | 1 |
| So, SY | 1 |
| Lam, WK | 1 |
| Kwan, S | 1 |
| Stott, DJ | 1 |
| Roberts, JA | 1 |
| Thomson, NC | 1 |
| Ball, SG | 1 |
2 trials available for ketanserin and Asthma
| Article | Year |
|---|---|
Effect of ketanserin, a new blocking agent of the 5-HT2 receptor, on airway responsiveness in asthma.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Child; Dose-Response Relationship, Immunologic; | 1990 |
The effects of the 5 HT2 antagonist ketanserin in adult atopic asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Double-Blind Method; Female; Forced Expiratory | 1988 |
3 other studies available for ketanserin and Asthma
| Article | Year |
|---|---|
Immediate allergic response in small airways.
Topics: Allergens; Animals; Asthma; Bronchial Diseases; Constriction, Pathologic; Disease Models, Animal; Dr | 2001 |
Do mucosal mast cells contribute to the immediate asthma response?
Topics: Animals; Asthma; Connective Tissue; Female; Histamine Release; Histocytochemistry; Immunoglobulin E; | 2001 |
Selective 5-HT2 receptor blockade in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Humans; Ketanserin; Piperidines | 1985 |