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ketanserin and Arteriosclerosis Obliterans

ketanserin has been researched along with Arteriosclerosis Obliterans in 4 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Arteriosclerosis Obliterans: Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of ketanserin treatment (40 mg daily for 90 days) was evaluated in 88 patients with arterial hypertension combined with Leriche-Fontaine stage II obliterating arterial disease of the lower limbs."9.07[Essential arterial hypertension and Leriche-Fontaine stage II obliterating vascular disease of the lower limbs. A new pharmacological approach with ketanserin]. ( Mollo, P, 1991)
"Ketanserin is a new strong antiserotoninergic drug that, unlike the previous ones, is selective for 5-hydroxytryptamine receptors."6.66Effects of ketanserin on blood pressure, peripheral circulation and haemocoagulative parameters in essential hypertensives with or without arteriosclerosis obliterans of the lower limbs. ( Abrignani, MG; Adamo, L; Alaimo, G; Avellone, G; Cutietta, A; Giordano, U; Indovina, A; Novo, S; Pinto, A; Strano, A, 1986)
"The efficacy of ketanserin treatment (40 mg daily for 90 days) was evaluated in 88 patients with arterial hypertension combined with Leriche-Fontaine stage II obliterating arterial disease of the lower limbs."5.07[Essential arterial hypertension and Leriche-Fontaine stage II obliterating vascular disease of the lower limbs. A new pharmacological approach with ketanserin]. ( Mollo, P, 1991)
"Ketanserin is a new strong antiserotoninergic drug that, unlike the previous ones, is selective for 5-hydroxytryptamine receptors."2.66Effects of ketanserin on blood pressure, peripheral circulation and haemocoagulative parameters in essential hypertensives with or without arteriosclerosis obliterans of the lower limbs. ( Abrignani, MG; Adamo, L; Alaimo, G; Avellone, G; Cutietta, A; Giordano, U; Indovina, A; Novo, S; Pinto, A; Strano, A, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gerritsen, HA1
Perquin, JW1
de Smet, HL1
Troost, FA1
Kotora, OV1
Mollo, P1
Regenthal, R1
Voigt, H1
Novo, S1
Alaimo, G1
Abrignani, MG1
Giordano, U1
Avellone, G1
Pinto, A1
Adamo, L1
Cutietta, A1
Indovina, A1
Strano, A1

Reviews

1 review available for ketanserin and Arteriosclerosis Obliterans

ArticleYear
[The clinical significance of serotonin antagonists].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Sep-01, Volume: 44, Issue:17

    Topics: Arteriosclerosis Obliterans; Humans; Hypertension; Ischemia; Ketanserin; Leg; Serotonin Antagonists

1989

Trials

2 trials available for ketanserin and Arteriosclerosis Obliterans

ArticleYear
[Essential arterial hypertension and Leriche-Fontaine stage II obliterating vascular disease of the lower limbs. A new pharmacological approach with ketanserin].
    La Clinica terapeutica, 1991, Apr-30, Volume: 137, Issue:2

    Topics: Aged; Aged, 80 and over; Arteriosclerosis Obliterans; Female; Humans; Hypertension; Ketanserin; Leg;

1991
Effects of ketanserin on blood pressure, peripheral circulation and haemocoagulative parameters in essential hypertensives with or without arteriosclerosis obliterans of the lower limbs.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:3

    Topics: Adult; Antihypertensive Agents; Arteriosclerosis Obliterans; Blood Coagulation; Blood Pressure; Doub

1986

Other Studies

1 other study available for ketanserin and Arteriosclerosis Obliterans

ArticleYear
Continuous imaging of regional blood flow in peripheral vascular disease using Krypton-81m: effect of Ketanserin, a new selective serotonin antagonist.
    Diagnostic imaging, 1983, Volume: 52, Issue:2-3

    Topics: Animals; Arteriosclerosis Obliterans; Cats; Diabetic Angiopathies; Female; Humans; Hyperemia; Ketans

1983