ketanserin has been researched along with Anxiety in 19 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/kg) on (i) anxiety-related behaviour in an elevated plus-maze, and (ii) specific [3H]ketanserin binding at central 5-HT2A receptors, in Roman rats." | 7.69 | Repeated DOI and SR 46349B treatments do not affect elevated plus-maze anxiety despite opposite effects on cortical 5-HT2A receptors. ( Chaouloff, F; Kulikov, A; Mormède, P, 1997) |
| "Psilocybin has been shown to improve symptoms of depression and anxiety when combined with psychotherapy or other clinician-guided interventions." | 4.31 | Acute psilocybin enhances cognitive flexibility in rats. ( Garza, G; Moghaddam, B; Olson, RJ; Torrado Pacheco, A, 2023) |
| "Control and maternally separated litters received treatment with the 5-HT(2) receptor antagonist, ketanserin, or vehicle during postnatal life and were examined for effects on adult anxiety behavior, adult stress-induced immediate early gene expression responses, and transcriptional changes within the prefrontal cortex during postnatal life and in adulthood." | 3.77 | Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress. ( Benekareddy, M; Nair, AR; Vadodaria, KC; Vaidya, VA, 2011) |
| "5 mg/kg) on (i) anxiety-related behaviour in an elevated plus-maze, and (ii) specific [3H]ketanserin binding at central 5-HT2A receptors, in Roman rats." | 3.69 | Repeated DOI and SR 46349B treatments do not affect elevated plus-maze anxiety despite opposite effects on cortical 5-HT2A receptors. ( Chaouloff, F; Kulikov, A; Mormède, P, 1997) |
| "The present work was devoted to the comparative analysis of influence of chronic administration of 5-HT(2B/2C) receptors agonist - m-CPP (0,5 mg/kg, i." | 1.38 | [Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats]. ( Fedotova, IuO; Frolova, HO; Ordian, NE; Soboliev, VI, 2012) |
| "Comparative study of the effects of chronic administration of 5-HT(2A/2C)-receptors agonist (m-CPP, 0." | 1.38 | [Behavioral effects of ketanserine in prenatally stressed female rats]. ( Fedotova, IuO; Ordian, NE; Pivina, SG, 2012) |
| "The aim of the present work was an estimation of influence of chronic administration of 5-receptors antagonist--NAN-190 (0." | 1.36 | [Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle]. ( Fedotova, IuO, 2010) |
| "A comparative analysis of the influence of chronic administration of the 5-HT2B/2C receptor agonist, m-CPP (0." | 1.36 | [Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats]. ( Fedotova, IuO, 2010) |
| "Aripiprazole is a first next-generation atypical antipsychotic drug with dopamine system stabilizing, serotonin (5-hydroxytryptamine, 5-HT) 5-HT1A receptor partial agonistic, and 5-HT2A receptor antagonistic properties." | 1.35 | Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms. ( Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Kurita, JPF | 1 |
| Leão, AHFF | 1 |
| Bioni, VS | 1 |
| Wuo-Silva, R | 1 |
| Lima, AC | 1 |
| Paiva-Santos, MA | 1 |
| Marinho, GF | 1 |
| Cunha, DMG | 1 |
| Becegato, M | 1 |
| Lopes-Silva, LB | 1 |
| Ribeiro, AM | 1 |
| Silva, RH | 1 |
| Torrado Pacheco, A | 1 |
| Olson, RJ | 1 |
| Garza, G | 1 |
| Moghaddam, B | 1 |
| Fedotova, IuO | 4 |
| Ordian, NE | 2 |
| Frolova, HO | 1 |
| Soboliev, VI | 1 |
| Nowicki, M | 1 |
| Tran, S | 1 |
| Muraleetharan, A | 1 |
| Markovic, S | 1 |
| Gerlai, R | 1 |
| de Paula, BB | 1 |
| Leite-Panissi, CR | 1 |
| Egashira, N | 1 |
| Okuno, R | 1 |
| Matsushita, M | 1 |
| Abe, M | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Nishimura, R | 1 |
| Oishi, R | 1 |
| Fujiwara, M | 1 |
| de Paula, DC | 1 |
| Torricelli, AS | 1 |
| Lopreato, MR | 1 |
| Nascimento, JO | 1 |
| Viana, MB | 1 |
| Benekareddy, M | 1 |
| Vadodaria, KC | 1 |
| Nair, AR | 1 |
| Vaidya, VA | 1 |
| McOmish, CE | 1 |
| Gingrich, JA | 1 |
| Pivina, SG | 1 |
| Nic Dhonnchadha, BA | 1 |
| Bourin, M | 1 |
| Hascoët, M | 1 |
| Sokal, DM | 1 |
| Giarola, AS | 1 |
| Large, CH | 1 |
| Nunes-de-Souza, V | 1 |
| Nunes-de-Souza, RL | 1 |
| Rodgers, RJ | 1 |
| Canto-de-Souza, A | 1 |
| Zangrossi Júnior, H | 1 |
| Graeff, FG | 1 |
| Kulikov, A | 2 |
| Aguerre, S | 1 |
| Berton, O | 1 |
| Ramos, A | 1 |
| Mormede, P | 2 |
| Chaouloff, F | 2 |
| Díaz-Véliz, G | 1 |
| Alarcón, T | 1 |
| Espinoza, C | 1 |
| Dussaubat, N | 1 |
| Mora, S | 1 |
19 other studies available for ketanserin and Anxiety
| Article | Year |
|---|---|
Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear Co | 2023 |
Acute psilocybin enhances cognitive flexibility in rats.
Topics: Animals; Anxiety; Cognition; Female; Hallucinogens; Ketanserin; Male; Psilocybin; Rats; Serotonin; S | 2023 |
[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats].
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Depression; Estrogens; Estrus; Fema | 2012 |
Serotonin antagonists induce anxiolytic and anxiogenic-like behavior in zebrafish in a receptor-subtype dependent manner.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Ketanserin; Ondansetron; Piperazi | 2014 |
Distinct effect of 5-HT1A and 5-HT2A receptors in the medial nucleus of the amygdala on tonic immobility behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Corticomedial Nuclear Complex; Fear; Guine | 2016 |
Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Anxiety; Aripiprazole; Behavi | 2008 |
[Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle].
Topics: Animals; Anxiety; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Estrous Cycle; Fem | 2010 |
[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; E | 2010 |
5-HT(2A) receptor activation in the dorsolateral septum facilitates inhibitory avoidance in the elevated T-maze.
Topics: Amphetamines; Animals; Anxiety; Avoidance Learning; Escape Reaction; Ketanserin; Male; Rats; Rats, W | 2012 |
Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Apoptosis Regulatory Proteins | 2011 |
Stress and the baby brain.
Topics: Animals; Anxiety; Female; Gene Expression Regulation; Ketanserin; Male; Pregnancy; Prenatal Exposure | 2011 |
[Behavioral effects of ketanserine in prenatally stressed female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Female; | 2012 |
Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety.
Topics: Amphetamines; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dose-Response Relations | 2003 |
Effects of GABA(B), 5-HT(1A), and 5-HT(2) receptor stimulation on activation and inhibition of the rat lateral amygdala following medial geniculate nucleus stimulation in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Amygdala; Animals; Anxiety; Baclofen; Evoked P | 2005 |
5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice.
Topics: Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Ketanserin; Male; Mesencephalo | 2008 |
Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; gamma-Aminobutyric Acid; Ketanserin; Male; Rats; R | 1994 |
Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Citalopram; Female; Hipp | 1997 |
Ketanserin and anxiety levels: influence of gender, estrous cycle, ovariectomy and ovarian hormones in female rats.
Topics: Animals; Anxiety; Avoidance Learning; Estrogens; Estrus; Female; Ketanserin; Male; Ovariectomy; Prog | 1997 |
Repeated DOI and SR 46349B treatments do not affect elevated plus-maze anxiety despite opposite effects on cortical 5-HT2A receptors.
Topics: Amphetamines; Animals; Anxiety; Behavior, Animal; Body Weight; Cerebral Cortex; Female; Fluorobenzen | 1997 |