Page last updated: 2024-10-29

ketanserin and Alloxan Diabetes

ketanserin has been researched along with Alloxan Diabetes in 10 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Research Excerpts

ExcerptRelevanceReference
"The streptozotocin-induced diabetic rat model was used to compare the efficacy of duloxetine, 5-HT, the 5-HT(2A) receptor agonist [1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)] and two antagonists (ketanserin and pruvanserin) on tactile allodynia."3.77A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. ( Jolivalt, CG; Mixcoatl-Zecuatl, T, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (70.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mixcoatl-Zecuatl, T1
Jolivalt, CG1
Miyata, S1
Hirano, S1
Kamei, J1
Banes, AK1
Shaw, SM1
Tawfik, A1
Patel, BP1
Ogbi, S1
Fulton, D1
Marrero, MB1
Sikorski, BW1
James, GM3
Glance, SD1
Hodgson, WC3
King, RG1
Takeshita, N3
Ohkubo, Y1
Yamaguchi, I3
Davis, EA1
Haynes, JM1
Sumiyoshi, T1
Ichikawa, J1
Meltzer, HY1

Other Studies

10 other studies available for ketanserin and Alloxan Diabetes

ArticleYear
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
    British journal of pharmacology, 2011, Volume: 164, Issue:1

    Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochlor

2011
Diabetes inhibits the DOI-induced head-twitch response in mice.
    Psychopharmacology, 2004, Volume: 177, Issue:1-2

    Topics: Amphetamines; Animals; Corticosterone; Diabetes Mellitus, Experimental; Head Movements; Ketanserin;

2004
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin.
    American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:4

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; Diabetes Mellitus, Experimental; DNA-Binding Proteins; En

2005
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3

    Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; I

1993
Tiapride attenuates pain transmission through an indirect activation of central serotonergic mechanism.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Animals; Central Nervous System; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dopamine An

1995
Attenuated 5-hydroxytryptamine receptor-mediated responses in aortae from streptozotocin-induced diabetic rats.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Animals; Aorta; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Ins

1994
Meta-chlorophenylpiperazine attenuates formalin-induced nociceptive responses through 5-HT1/2 receptors in both normal and diabetic mice.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Formaldehyde; Indoles; Ketanser

1995
Attenuated 5-HT2 receptor-mediated responses in hindquarters of diabetic rats.
    European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1

    Topics: Animals; Arachidonic Acid; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experiment

1995
Insulin attenuates formalin-induced nociceptive response in mice through a mechanism that is deranged by diabetes mellitus.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Analgesics; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Indoles;

1997
The effect of streptozotocin-induced diabetes on dopamine2, serotonin1A and serotonin2A receptors in the rat brain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diabetes Mellitus, Experimental; Dopamine An

1997