ketanserin has been researched along with Alloxan Diabetes in 10 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Excerpt | Relevance | Reference |
---|---|---|
"The streptozotocin-induced diabetic rat model was used to compare the efficacy of duloxetine, 5-HT, the 5-HT(2A) receptor agonist [1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)] and two antagonists (ketanserin and pruvanserin) on tactile allodynia." | 3.77 | A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. ( Jolivalt, CG; Mixcoatl-Zecuatl, T, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (70.00) | 18.2507 |
2000's | 2 (20.00) | 29.6817 |
2010's | 1 (10.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mixcoatl-Zecuatl, T | 1 |
Jolivalt, CG | 1 |
Miyata, S | 1 |
Hirano, S | 1 |
Kamei, J | 1 |
Banes, AK | 1 |
Shaw, SM | 1 |
Tawfik, A | 1 |
Patel, BP | 1 |
Ogbi, S | 1 |
Fulton, D | 1 |
Marrero, MB | 1 |
Sikorski, BW | 1 |
James, GM | 3 |
Glance, SD | 1 |
Hodgson, WC | 3 |
King, RG | 1 |
Takeshita, N | 3 |
Ohkubo, Y | 1 |
Yamaguchi, I | 3 |
Davis, EA | 1 |
Haynes, JM | 1 |
Sumiyoshi, T | 1 |
Ichikawa, J | 1 |
Meltzer, HY | 1 |
10 other studies available for ketanserin and Alloxan Diabetes
Article | Year |
---|---|
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochlor | 2011 |
Diabetes inhibits the DOI-induced head-twitch response in mice.
Topics: Amphetamines; Animals; Corticosterone; Diabetes Mellitus, Experimental; Head Movements; Ketanserin; | 2004 |
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Diabetes Mellitus, Experimental; DNA-Binding Proteins; En | 2005 |
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; I | 1993 |
Tiapride attenuates pain transmission through an indirect activation of central serotonergic mechanism.
Topics: Animals; Central Nervous System; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dopamine An | 1995 |
Attenuated 5-hydroxytryptamine receptor-mediated responses in aortae from streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Ins | 1994 |
Meta-chlorophenylpiperazine attenuates formalin-induced nociceptive responses through 5-HT1/2 receptors in both normal and diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Formaldehyde; Indoles; Ketanser | 1995 |
Attenuated 5-HT2 receptor-mediated responses in hindquarters of diabetic rats.
Topics: Animals; Arachidonic Acid; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experiment | 1995 |
Insulin attenuates formalin-induced nociceptive response in mice through a mechanism that is deranged by diabetes mellitus.
Topics: Analgesics; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Indoles; | 1997 |
The effect of streptozotocin-induced diabetes on dopamine2, serotonin1A and serotonin2A receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diabetes Mellitus, Experimental; Dopamine An | 1997 |