ketanserin has been researched along with Alcoholism in 8 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketanserin is a pure antagonist of serotonin S2-receptors, in blood vessels, platelets and bronchial tissue." | 5.27 | Ketanserin (S2-receptor blocking agents), hypertension and chronic alcoholism. ( Assogna, G; Ceccanti, M; De Lorenzo, A; Di Giovanni, MG; Lais, A; Pisculli, M; Romeo, M; Valgiusti, FC, 1986) |
| "Ketanserin treatment tended to normalize these protein levels in such patients." | 5.27 | Ketanserin (S2-receptor blocking agent), platelet activity and chronic alcoholism. ( Attilia, ML; Berbellini, A; Cavaleri, G; Ceccanti, M; De Lorenzo, A; Di Giovanni, MG; Pisculli, M; Santini, P, 1986) |
| "Ketanserin is a pure antagonist of serotonin S2-receptors, in blood vessels, platelets and bronchial tissue." | 1.27 | Ketanserin (S2-receptor blocking agents), hypertension and chronic alcoholism. ( Assogna, G; Ceccanti, M; De Lorenzo, A; Di Giovanni, MG; Lais, A; Pisculli, M; Romeo, M; Valgiusti, FC, 1986) |
| "Ketanserin treatment tended to normalize these protein levels in such patients." | 1.27 | Ketanserin (S2-receptor blocking agent), platelet activity and chronic alcoholism. ( Attilia, ML; Berbellini, A; Cavaleri, G; Ceccanti, M; De Lorenzo, A; Di Giovanni, MG; Pisculli, M; Santini, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Storvik, M | 1 |
| Häkkinen, M | 1 |
| Tupala, E | 1 |
| Tiihonen, J | 1 |
| Underwood, MD | 1 |
| Mann, JJ | 1 |
| Huang, YY | 1 |
| Arango, V | 1 |
| Ciccocioppo, R | 1 |
| Ge, J | 1 |
| Barnes, NM | 1 |
| Cooper, SJ | 1 |
| Ulrichsen, J | 1 |
| De Lorenzo, A | 4 |
| Ceccanti, M | 4 |
| Assogna, G | 3 |
| Romeo, M | 3 |
| Cavalieri, G | 1 |
| Attilia, ML | 3 |
| Pisculli, M | 2 |
| Di Giovanni, MG | 2 |
| Lais, A | 1 |
| Valgiusti, FC | 1 |
| Santini, P | 1 |
| Cavaleri, G | 2 |
| Berbellini, A | 1 |
2 trials available for ketanserin and Alcoholism
| Article | Year |
|---|---|
Ketanserin hypertension and chronic alcoholism DB study in 40 patients.
Topics: Alcoholism; Blood Pressure; Chronic Disease; Female; Humans; Hypertension; Ketanserin; Male; Piperid | 1985 |
Ketanserin, hypertension, and chronic alcoholism: double-blind study in forty patients.
Topics: Adult; Aged; Alcoholism; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Huma | 1988 |
6 other studies available for ketanserin and Alcoholism
| Article | Year |
|---|---|
Whole-hemisphere autoradiography of 5-HT₁B receptor densities in postmortem alcoholic brains.
Topics: Adult; Age Factors; Aged; Alcoholism; Analysis of Variance; Autoradiography; Brain; Female; Function | 2012 |
Family history of alcoholism is associated with lower 5-HT2A receptor binding in the prefrontal cortex.
Topics: Adolescent; Adult; Aged; Alcoholism; Case-Control Studies; Female; Genetic Predisposition to Disease | 2008 |
Autoradiographic mapping of brain 5-HT2A binding sites in P and in AA alcohol-preferring rats.
Topics: Alcoholism; Animals; Autoradiography; Brain; Brain Mapping; Ketanserin; Male; Rats; Receptors, Serot | 1997 |
Alterations in serotonin receptor subtypes in ethanol-dependent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcohol | 1991 |
Ketanserin (S2-receptor blocking agents), hypertension and chronic alcoholism.
Topics: Adult; Alcoholism; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Ketanserin | 1986 |
Ketanserin (S2-receptor blocking agent), platelet activity and chronic alcoholism.
Topics: Adult; Alcoholism; beta-Thromboglobulin; Female; Humans; Ketanserin; Male; Middle Aged; Piperidines; | 1986 |