ketanserin has been researched along with Acute Respiratory Distress Syndrome in 9 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Porcine Pseudomonas adult respiratory distress syndrome (ARDS) has been shown to respond to combination therapy of 150 mg of cimetidine, 12." | 3.67 | Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model. ( Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL, 1987) |
| "The effects of the serotonin receptor blocker, ketanserin, were studied in a porcine Pseudomonas adult respiratory distress syndrome model." | 3.67 | Serotonin receptor blockade improves cardiac output and hypoxia in porcine ARDS. ( Kellum, JM; Kuemmerle, JF; Sielaff, TD; Sugerman, HJ; Tatum, JL, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hechtman, HB | 1 |
| Valeri, CR | 1 |
| Shepro, D | 1 |
| Kalenda, Z | 1 |
| Hölzenspies, AJ | 1 |
| Kesecioglu, J | 1 |
| Ince, C | 1 |
| Pompe, JC | 1 |
| Gültuna, I | 1 |
| Erdmann, W | 1 |
| Bruining, HA | 1 |
| Egermayer, P | 1 |
| Town, GI | 1 |
| Peacock, AJ | 1 |
| Sielaff, TD | 3 |
| Sugerman, HJ | 3 |
| Tatum, JL | 3 |
| Blocher, CR | 2 |
| Radermacher, P | 1 |
| Huet, Y | 1 |
| Pluskwa, F | 1 |
| Herigault, R | 1 |
| Mal, H | 1 |
| Teisseire, B | 1 |
| Lemaire, F | 1 |
| Heinrichs, W | 1 |
| Fauth, U | 1 |
| Kellum, JM | 2 |
| Kuemmerle, JF | 1 |
2 reviews available for ketanserin and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Role of humoral mediators in adult respiratory distress syndrome.
Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Chromones; Dogs; Guinea Pigs; Humans; Hypertensio | 1984 |
Role of serotonin in the pathogenesis of acute and chronic pulmonary hypertension.
Topics: Blood Platelet Disorders; Collagen Diseases; Humans; Hypertension, Portal; Hypertension, Pulmonary; | 1999 |
7 other studies available for ketanserin and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Restoration of pulmonary perfusion by a serotonin antagonist.
Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Embolism, Air; Female; Humans; Infant, Newborn; Intraop | 1981 |
Effect of ketanserine on oxygenation and ventilation inhomogeneity in pigs with ARDS.
Topics: Animals; Bronchoconstriction; Disease Models, Animal; Hemodynamics; Ketanserin; Oxygen Consumption; | 1994 |
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin | 1987 |
Comparison of ketanserin and sodium nitroprusside in patients with severe ARDS.
Topics: Adult; Ferricyanides; Humans; Ketanserin; Middle Aged; Nitroprusside; Pulmonary Circulation; Pulmona | 1988 |
Extravascular lung water and pulmonary artery pressure with acute respiratory failure--effect of ketanserin administration.
Topics: Acute Disease; Extracellular Space; Humans; Ketanserin; Lung; Pulmonary Wedge Pressure; Respiratory | 1987 |
Serotonin receptor blockade improves cardiac output and hypoxia in porcine ARDS.
Topics: Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Histamine Antagonists; Hypoxia; Ket | 1987 |
Treatment of porcine Pseudomonas ARDS with combination drug therapy.
Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug C | 1987 |