ketamine has been researched along with Wounds and Injuries in 84 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine PCA led to lower cumulative opioid consumption and lower oxygen supplementation requirements, though hallucinations occurred more frequently with use of ketamine." | 9.27 | Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients. ( Branson, RD; Droege, CA; Droege, ME; Ernst, N; Gerlach, TW; Johannigman, JA; Mueller, EW; Robinson, BRH; Takieddine, SC; Webb, M, 2018) |
| "This study was a long-term follow-up study of the prehospital, prospective, randomised, controlled, open-label study comparing ketamine with morphine in patients with trauma and a verbal pain score of >5 after 5 mg intravenous morphine." | 9.19 | Long-term pain prevalence and health-related quality of life outcomes for patients enrolled in a ketamine versus morphine for prehospital traumatic pain randomised controlled trial. ( Bernard, S; Cameron, P; Fitzgerald, M; Jennings, PA; Jolley, D; Masci, K; Walker, T, 2014) |
| "The purpose of this study was to evaluate differences in pain intensity, pain quality, physiological measures, and adverse effects when patients received morphine with saline (MS) compared with morphine and a small dose of ketamine (MK) before an open wound care procedure (WCP)." | 9.15 | Efficacy of small doses of ketamine with morphine to decrease procedural pain responses during open wound care. ( Arroyo-Novoa, CM; Figueroa-Ramos, MI; Miaskowski, C; Padilla, G; Paul, SM; Puntillo, KA; Rodríguez-Ortiz, P; Stotts, NA, 2011) |
| "The aim of the study was to compare in emergency settings 2 analgesic regimens, morphine with ketamine (K group) or morphine with placebo (P group), for severe acute pain in trauma patients." | 9.12 | Management of severe acute pain in emergency settings: ketamine reduces morphine consumption. ( Adnet, F; Catineau, J; Combes, X; Dolveck, F; Galinski, M; Lapostolle, F; Limoges, V; Pommier, V; Smaïl, N; Templier, F, 2007) |
| " The goal of this study was to evaluate the off-label use of rectally administered S(+)-ketamine and Midazolam by paediatric surgeons during repeated outpatient dressing changes for paediatric burns and scalding." | 9.11 | Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries. ( Heinrich, M; Muensterer, OJ; Till, H; Wetzstein, V, 2004) |
| " A few small studies in patients have suggested that intravenous boluses or rapid infusions of the N-methyl-D-aspartate (NMDA) antagonist ketamine relieve some neuropathic pains but also produce disturbances of cognition and mood." | 9.08 | Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo. ( Bennett, GJ; Byas-Smith, MG; Gracely, RH; Max, MB, 1995) |
| "Low-dose ketamine infusions for complex combat injury pain were safe and effective, and demonstrated response patterns over time and by baseline pain score stratification and presence or absence of PLP." | 7.79 | Effects of low-dose IV ketamine on peripheral and central pain from major limb injuries sustained in combat. ( Buckenmaier, CC; Gallagher, RM; Goldberg, C; Hanlon, AL; Kwon, KH; Polomano, RC; Rupprecht, C, 2013) |
| "Continuous intravenous infusions of ketamine and pentazocine have been used to provide analgesia in 18 patients with acute war injuries." | 7.67 | Infusion analgesia for acute war injuries. A comparison of pentazocine and ketamine. ( Bion, JF, 1984) |
| "His pain was diagnosed as neuropathic pain (complex regional pain syndrome, type II)." | 5.30 | The NMDA-receptor antagonist ketamine abolishes neuropathic pain after epidural administration in a clinical case. ( Miyazaki, M; Morita, S; Nanbu, T; Takahashi, H; Yanagida, H, 1998) |
| "Ketamine PCA led to lower cumulative opioid consumption and lower oxygen supplementation requirements, though hallucinations occurred more frequently with use of ketamine." | 5.27 | Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients. ( Branson, RD; Droege, CA; Droege, ME; Ernst, N; Gerlach, TW; Johannigman, JA; Mueller, EW; Robinson, BRH; Takieddine, SC; Webb, M, 2018) |
| "This study was a long-term follow-up study of the prehospital, prospective, randomised, controlled, open-label study comparing ketamine with morphine in patients with trauma and a verbal pain score of >5 after 5 mg intravenous morphine." | 5.19 | Long-term pain prevalence and health-related quality of life outcomes for patients enrolled in a ketamine versus morphine for prehospital traumatic pain randomised controlled trial. ( Bernard, S; Cameron, P; Fitzgerald, M; Jennings, PA; Jolley, D; Masci, K; Walker, T, 2014) |
| "The purpose of this study was to evaluate differences in pain intensity, pain quality, physiological measures, and adverse effects when patients received morphine with saline (MS) compared with morphine and a small dose of ketamine (MK) before an open wound care procedure (WCP)." | 5.15 | Efficacy of small doses of ketamine with morphine to decrease procedural pain responses during open wound care. ( Arroyo-Novoa, CM; Figueroa-Ramos, MI; Miaskowski, C; Padilla, G; Paul, SM; Puntillo, KA; Rodríguez-Ortiz, P; Stotts, NA, 2011) |
| "The aim of the study was to compare in emergency settings 2 analgesic regimens, morphine with ketamine (K group) or morphine with placebo (P group), for severe acute pain in trauma patients." | 5.12 | Management of severe acute pain in emergency settings: ketamine reduces morphine consumption. ( Adnet, F; Catineau, J; Combes, X; Dolveck, F; Galinski, M; Lapostolle, F; Limoges, V; Pommier, V; Smaïl, N; Templier, F, 2007) |
| " The goal of this study was to evaluate the off-label use of rectally administered S(+)-ketamine and Midazolam by paediatric surgeons during repeated outpatient dressing changes for paediatric burns and scalding." | 5.11 | Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries. ( Heinrich, M; Muensterer, OJ; Till, H; Wetzstein, V, 2004) |
| " A few small studies in patients have suggested that intravenous boluses or rapid infusions of the N-methyl-D-aspartate (NMDA) antagonist ketamine relieve some neuropathic pains but also produce disturbances of cognition and mood." | 5.08 | Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo. ( Bennett, GJ; Byas-Smith, MG; Gracely, RH; Max, MB, 1995) |
| " Ketamine, a N-methyl D-aspartate (NMDA) receptor antagonist, has been commonly used in the prehospital setting, including recommendations by the US Department of Defense and by the Royal Australian College of Pain Medicine, despite the paucity of high-level evidence." | 5.05 | Ketamine as a Prehospital Analgesic: A Systematic Review. ( Bansal, A; Burns, B; Ferguson, I; Miller, M, 2020) |
| "Outcomes were the recording of a pain score and the administration of a nonoral opioid or ketamine." | 4.31 | Race and Ethnicity and Prehospital Use of Opioid or Ketamine Analgesia in Acute Traumatic Injury. ( Brunson, DC; Carrillo, E; Matheson, LW; Miller, KA, 2023) |
| " Compared to pentazocine, ketamine was associated with improved blood pressure for patients with serious injuries." | 3.81 | Ketamine for prehospital trauma analgesia in a low-resource rural trauma system: a retrospective comparative study of ketamine and opioid analgesia in a ten-year cohort in Iraq. ( Husum, H; Losvik, OK; Murad, MK; Skjerve, E, 2015) |
| "Unit medical protocols authorize ketamine for tourniquet pain, amputations, long-bone fractures, and pain refractory to other agents." | 3.80 | Prehospital analgesia with ketamine for combat wounds: a case series. ( Conklin, CC; Fisher, AD; Mabry, RL; Rippee, B; Shehan, H, 2014) |
| "Low-dose ketamine infusions for complex combat injury pain were safe and effective, and demonstrated response patterns over time and by baseline pain score stratification and presence or absence of PLP." | 3.79 | Effects of low-dose IV ketamine on peripheral and central pain from major limb injuries sustained in combat. ( Buckenmaier, CC; Gallagher, RM; Goldberg, C; Hanlon, AL; Kwon, KH; Polomano, RC; Rupprecht, C, 2013) |
| " For patients with multiple injuries and for those patients requiring manipulation and splintage of fractures and for entrapments and difficult extrications ketamine is a safe and effective option, which avoids the potential decrease in blood pressure and respiratory depression that is associated with opioid analgesia." | 3.72 | Ketamine in prehospital care. ( Porter, K, 2004) |
| "To 51 women and 87 men in the age of 9-95 years who suffered from pain due to trauma and needed pain relief during transport to the hospital, a low dose of ketamine was given according to protocol." | 3.69 | [Analgetic ketamine feasible in ambulance emergency care]. ( Ansem, RP; Foudraine, JF; Hartman, JA; Rutten, FL; van Loenen, E, 1994) |
| "A total of 29 peafowl (Pavo cristatus), rectified surgically for infraorbital abscesses (n = 22), lacerated wounds (n = 4), and fractures of tibia (n = 2) and radius (n = 1), were anaesthetized by the intravenous administration of ketamine hydrochloride (Inj." | 3.69 | Clinical perspectives of intravenous ketamine anaesthesia in peafowl (Pavo cristatus). ( Athar, M; Chaudhry, NI; Muhammad, G; Sarwar, MN; Shakoor, A, 1996) |
| "Continuous intravenous infusions of ketamine and pentazocine have been used to provide analgesia in 18 patients with acute war injuries." | 3.67 | Infusion analgesia for acute war injuries. A comparison of pentazocine and ketamine. ( Bion, JF, 1984) |
| "Using Department of Defense Trauma Registry data for the Afghanistan conflict from 2005 to 2018, we examined 2,402 records of prehospital analgesia administration to assess temporal trends in medication choice and proportions receiving analgesia, including subanalysis of a cohort screened for an indication with minimal contraindication for analgesia." | 3.01 | Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan. ( Burgess, M; Hinojosa-Laborde, C; Hudson, IL; Newberry, RK; Ryan, KL; Schauer, SG; Staudt, AM; VanFosson, CA, 2023) |
| "001) but times from dosing to discharge (medians 105 and 110 minutes) were similar." | 2.70 | Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine. ( Kendall, JM; Younge, PA, 2001) |
| "Ketamine is a safe and effective sedative agent for use in children requiring immobilization to enable performance of a painful procedure." | 2.70 | Ketamine sedation for children in the emergency department. ( Francis, P; McAdam, CM; Priestley, SJ; Taylor, J, 2001) |
| "The surgical wound hyperalgesia was assessed by measuring pain threshold to pressure on the wound by using an algometer, and also by measuring the intensity of pain to suprathreshold pressure on the wound with the visual analog self-rating method." | 2.67 | Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. ( Bradley, EL; Finger, J; Isakson, A; Kissin, I; Oz, Y; Tverskoy, M, 1994) |
| "Twenty traumatized patients suffering from fractures and soft tissue injury were given either 0." | 2.66 | [Intravenous analgesia with ketamine for emergency patients]. ( Hirlinger, WK; Pfenninger, E, 1987) |
| "Twenty traumatized patients suffering from burns, fractures and bruises were given either 0." | 2.65 | [Intramuscular ketamine analgesia in emergency patients. II. Clinical study of traumatized patients]. ( Dick, W; Hirlinger, WK, 1984) |
| " However, the optimal dosing and route of administration and the safety of chronic treatment are not fully known." | 2.52 | Ketamine as a promising prototype for a new generation of rapid-acting antidepressants. ( Abdallah, CG; Averill, LA; Krystal, JH, 2015) |
| "Minor traumatic injuries are common in pregnancy, often subsequently requiring painful diagnostic and therapeutic procedures." | 2.49 | Safety of procedural sedation in pregnancy. ( Koren, G; Neuman, G, 2013) |
| "Ketamine is a safe and effective analgesic agent." | 2.47 | Ketamine as an analgesic in the pre-hospital setting: a systematic review. ( Bernard, S; Cameron, P; Jennings, PA, 2011) |
| "There was no external evidence of trauma." | 2.40 | Review of exertional rhabdomyolysis and a case in a rhesus monkey (Macaca mulatta). ( Chrisp, CE; Dysko, RC; Reuter, JD, 1998) |
| "Ketamine is an effective drug for battlefield analgesia." | 1.48 | Ketamine for military prehospital analgesia and sedation in combat casualties. ( Moy, R; Wright, C, 2018) |
| " Secondary objectives were to identify the patient population in which ketamine was initiated, assess the proportion of time patients were at their goal level of sedation, and determine the dosing patterns of adjunctive sedative agents." | 1.46 | Impact of Ketamine Use on Adjunctive Analgesic and Sedative Medications in Critically Ill Trauma Patients. ( Chui, SJ; Harbourt, K; Pajoumand, M; Pruskowski, KA; Reynolds, HN, 2017) |
| "Ketamine has emerged as an alternative for rapid sequence intubation induction." | 1.46 | Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients. ( Barrett, TW; Collins, SP; Ehrenfeld, JM; Grijalva, CG; High, K; Liu, D; McNaughton, CD; Rice, TW; Russ, S; Self, WH; Semler, MW; Upchurch, CP, 2017) |
| "Ketamine is an N-methyl-d-aspartate (NMDA) receptor antagonist that provides potent analgesia without noticeable respiratory depression." | 1.43 | COMPARISON OF INTRAOPERATIVE KETAMINE VS. FENTANYL USE DECREASES POSTOPERATIVE OPIOID REQUIREMENTS IN TRAUMA PATIENTS UNDERGOING CERVICAL SPINE SURGERY. ( Angus, GL; Berkowitz, AC; Ginsburg, AM; Ginsburg, DB; Kang, A; Pesso, RM, 2016) |
| "In military and civilian trauma, the IO route is often used to obtain rapid and reliable parenteral access for drug administration." | 1.42 | Rapid sequence induction of anaesthesia via the intraosseous route: a prospective observational study. ( Barnard, EB; Bebarta, VS; Kehoe, AD; Moy, RJ; Smith, JE, 2015) |
| " The mean midazolam dosage administered was 1 ± 0." | 1.40 | [Prehospital analgesia performed by paramedics: quality in processes and effects under medical supervision]. ( Gaier, G; Häske, D; Niederberger, C; Schempf, B, 2014) |
| " Dosing in the KET group was appropriate with a mean dose of 1." | 1.38 | A standardized rapid sequence intubation protocol facilitates airway management in critically injured patients. ( Anderson, S; Ballow, SL; Chang, M; Kaups, KL, 2012) |
| "Ketamine was found in 28 of these cases, signifying the popularity of this drug in Taiwan." | 1.35 | Methylenedioxymethamphetamine-related deaths in Taiwan: 2001-2008. ( Lin, DL; Liu, HC; Liu, RH, 2009) |
| "Ketamine was predominantly used in awake non-trapped patients with blunt trauma for procedural sedation and analgesia." | 1.35 | Pre-hospital use of ketamine in paediatric trauma. ( Bredmose, PP; Davies, GE; Grier, G; Lockey, DJ, 2009) |
| "Ketamine was mainly used in awake non-trapped patients with blunt trauma for procedural sedation and analgesia." | 1.35 | Pre-hospital use of ketamine for analgesia and procedural sedation. ( Bredmose, PP; Davies, G; Grier, G; Lockey, DJ; Watts, B, 2009) |
| "Ketamine was given, either intramuscularly (3-4 mg/kg) or intravenously (1-2 mg/kg) together with atropine (0." | 1.31 | Sedation with ketamine for paediatric procedures in the emergency department--a review of 500 cases. ( Ang, SY; Ng, KC, 2002) |
| "His pain was diagnosed as neuropathic pain (complex regional pain syndrome, type II)." | 1.30 | The NMDA-receptor antagonist ketamine abolishes neuropathic pain after epidural administration in a clinical case. ( Miyazaki, M; Morita, S; Nanbu, T; Takahashi, H; Yanagida, H, 1998) |
| "Altogether 102 children with simple wounds between 1 and 7 years old were allocated to the two study groups." | 1.30 | An alternative to "brutacaine": a comparison of low dose intramuscular ketamine with intranasal midazolam in children before suturing. ( Durham, S; McGlone, RG; Ranasinghe, S, 1998) |
| "Ketamine and midazolam were used for induction of anaesthesia and by continuous intravenous infusion for maintenance to assess their suitability for use in a total intravenous anaesthetic technique in the management of battle casualties." | 1.27 | Total intravenous anaesthesia for military surgery. A technique using ketamine, midazolam and vecuronium. ( Kidd, AG; Restall, J; Tully, AM; Ward, PJ, 1988) |
| " The dosage of anesthetic agents was calculated according to body weight." | 1.27 | [Combined midazolam-ketamine anesthesia in traumatologic interventions. Patterns of endocrine reactions]. ( Bornscheuer, A; Hamkens, A; Lübbe, N; Seitz, W, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (22.62) | 18.7374 |
| 1990's | 11 (13.10) | 18.2507 |
| 2000's | 22 (26.19) | 29.6817 |
| 2010's | 27 (32.14) | 24.3611 |
| 2020's | 5 (5.95) | 2.80 |
| Authors | Studies |
|---|---|
| Hudson, IL | 1 |
| Staudt, AM | 1 |
| Burgess, M | 1 |
| Hinojosa-Laborde, C | 1 |
| Schauer, SG | 1 |
| Newberry, RK | 1 |
| Ryan, KL | 1 |
| VanFosson, CA | 1 |
| Brunson, DC | 1 |
| Miller, KA | 1 |
| Matheson, LW | 1 |
| Carrillo, E | 1 |
| Häske, D | 2 |
| Böttiger, BW | 1 |
| Bouillon, B | 1 |
| Fischer, M | 1 |
| Gaier, G | 2 |
| Gliwitzky, B | 1 |
| Helm, M | 1 |
| Hilbert-Carius, P | 1 |
| Hossfeld, B | 1 |
| Schempf, B | 2 |
| Wafaisade, A | 1 |
| Bernhard, M | 1 |
| Bansal, A | 1 |
| Miller, M | 1 |
| Ferguson, I | 1 |
| Burns, B | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Patient-Controlled Analgesia for Acute Pain in Native Airway Multiple and Orthopedic Trauma Patients: A Randomized, Active Comparator, Blinded Trial[NCT02062879] | Phase 3 | 20 participants (Actual) | Interventional | 2014-04-30 | Terminated (stopped due to Withdrawals from study due to anticipated effects from study drugs) | ||
| (2R,6R)-Hydroxynorketamine a Novel Therapeutic Analgesic for the Treatment of Neuropathic Pain: A Randomized Double Blind Cross-Over Trial.[NCT05864053] | Phase 1/Phase 2 | 25 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| A Combination Study With Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain in the Emergency Department[NCT03959852] | Phase 4 | 6 participants (Actual) | Interventional | 2019-11-18 | Terminated (stopped due to Residency completed.) | ||
| Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department[NCT03996564] | 26 participants (Actual) | Interventional | 2016-02-22 | Completed | |||
| Prospective Study of Induction Medications Used in the Rapid Sequence Intubation of Trauma Patients and a Comparison of Effects on Outcomes[NCT04291521] | 7,000 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| Comparing the Effectiveness of Low-dose Ketamine With Morphine to Treat Pain in Patients With Long Bone Fractures[NCT02430818] | 13 participants (Actual) | Interventional | 2015-04-30 | Terminated (stopped due to were not able to enroll patients to a satisfactory level) | |||
| Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114] | Phase 4 | 120 participants (Actual) | Interventional | 2017-11-06 | Completed | ||
| ED Treatment of Suicidal Patients With Ketamine Infusion[NCT03502551] | Phase 2 | 0 participants (Actual) | Interventional | 2019-04-01 | Withdrawn (stopped due to Trial never received funding.) | ||
| Comparison of Two Methods Using Intranasal Lidocaine to Alleviate Discomfort Associated With Administration of Intranasal Midazolam in Children.[NCT03054844] | Phase 2 | 55 participants (Actual) | Interventional | 2017-04-03 | Completed | ||
| A Prospective Randomized Double Blind Evaluation of Ketamine/Propofol vs Ketamine Alone for Pediatric Extremity Fracture Reduction[NCT00490997] | Phase 4 | 140 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050] | Phase 4 | 50 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control[NCT04698772] | 32 participants (Actual) | Observational | 2019-12-19 | Completed | |||
| Intranasal Ketamine Versus Subcutaneous Ketamine for Treatment of Post Traumatic Acute Pain in the Emergency Department[NCT05229055] | Phase 2/Phase 3 | 1,000 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | ||
| Ketamine For Acute Treatment of Pain in Emergency Department[NCT02306759] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Comparison of Intravenous Push Dose of Low Dose Ketamine to Short Infusion of Low Dose Ketamine for Treatment of Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study[NCT02363270] | 48 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department[NCT02489630] | Phase 4 | 116 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study[NCT01835262] | Phase 4 | 90 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Low-Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department Geriatric Population: A Prospective, Randomized, Double-Blind Study.[NCT02673372] | Phase 4 | 60 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Comparison of Ketamine 0.1 mg/kg, 0.2 mg/kg, and 0.3 mg/kg Intravenous Doses for Acute Pain in the Emergency Department: A Prospective, Randomized, Double-blind, Active-controlled, Clinical Trial[NCT03896230] | Phase 4 | 11 participants (Actual) | Interventional | 2019-05-03 | Terminated (stopped due to Due to resource limitations the study was on hold and was then terminated.) | ||
| Study of the Efficiency of the Ketamine With Low Analgesic Doses, in Association With High Opioids, in the Treatment of the Rebels Pains, in Palliative Phase of the Cancerous Disease[NCT01326325] | Phase 3 | 24 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Breakthrough daily opioid requirement in milligrams of morphine equivalents/day (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week
| Intervention | mg morphine equivalents/day (Median) |
|---|---|
| Ketamine | 10 |
| Hydromorphone | 10 |
Median daily pain score measures on a visual analogue scale for pain, with a range of 0 to 10. Higher scored indicate worse pain. (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week
| Intervention | scores on a scale (Median) |
|---|---|
| Ketamine | 6.3 |
| Hydromorphone | 5.3 |
Daily breakthrough opioid requirement plus non-breakthrough opioid use in milligrams of morphine equivalents (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week.
| Intervention | mg morphine equivalents/day (Median) |
|---|---|
| Ketamine | 10 |
| Hydromorphone | 42.5 |
We will monitor for adverse effects and record for changes in vital signs including nausea and vomiting, hypotension, respiratory depression, laryngospasm, and emotional and psychological effects (emergence reactions). (NCT02430818)
Timeframe: 60 minutes
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Morphine | 1 |
Study outcomes involve change in participants' pain as measured by a visual analog scale. The scale is a 10 inch line from 0 to 10 inches with 10 being the most pain and 0 being no pain. There are no units on the scale; it is just a straight line from no pain (0) to the worst pain (10). We assessed at o, 15, and 60 minutes but only scored the VAS at 60 minutes. (NCT02430818)
Timeframe: At 0 minutes and 60 minutes
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 4 |
| Morphine | 4 |
Patients will be assessed to determine whether the participant would consider using the drug given to them for pain relief in the future. It was measured on a likert scale from 1-5 with 1 being did not like and would not use the drug again to 5 being like and would definitely receive the medication again. There are no units. The numbers below are the total number of patients that completed this answer. This was only asked on patients that received medication as if they did not receive medication the answer would not make sense. The median value is the likert value on a scale of 1-5 with the standard deviation. (NCT02430818)
Timeframe: 60 minutes
| Intervention | units on a scale (Median) |
|---|---|
| Ketamine | 4 |
| Morphine | 4 |
If my child needed medications to stay calm for a procedure, I would like to use these same medications again. (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 10 |
| PREMIX | 12 |
Cry duration was measured in seconds and defined as the time from onset of crying following administration of an IN medication until the cessation of crying sounds and/or tears. If a patient did not cry, the cry duration was zero (NCT03054844)
Timeframe: 10 minutes
| Intervention | seconds (Mean) |
|---|---|
| PREMED | 84 |
| PREMIX | 73 |
The Faces, Legs, Activity, Cry, Consolability (FLACC) scale is comprised of five criteria (face, legs, activity, cry, consolability), with a possible score of 0 to 2 units on a scale for each criteria and a possible total score of 0 to 10 units on a scale (0 meaning no pain, 10 meaning most pain). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.7 |
| PREMIX | 7 |
The Observational Scale of Behavioral Distress-Revised (OSBD-R) is an observational measure of pain and distress shown to have strong validity in children. The scale is an 8-factor, weighted observational scale used to measure distress associated with medical procedures, which has been validated in children and adults aged 1 to 20 years. The total Observational Scale of Behavioral Distress-Revised score is the sum of the scale scores for each phase, with each phase assigned a score from 0 to 23.5 units on a scale (0=no distress, 23.5=maximum distress), based on the frequency and types of behaviors observed during a predetermined number of 15-second intervals during each phase. There were four phases so the range of scores for the total OSBD-R was 0 to 94 units on a scale, with a higher score indicated a greater degree of distress. (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.4 |
| PREMIX | 7 |
The Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) utilizes six observational factors (cry, facial, verbal, torso, touch, and legs) to evaluate pain in young children and can be used to monitor the effectiveness of interventions for reducing the pain and discomfort of an intervention. This scale rates each behavior numerically, with a score of 4-6 units on a scale representing no pain, and a maximum score of 13 units on a scale representing (most pain perceived). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 10.6 |
| PREMIX | 10.5 |
I would like to use this method of administering intranasal midazolam and lidocaine again in the future (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 8 |
| PREMIX | 24 |
Change from Baseline of Pain as described by Numeric Rating Scale (NRS) [minimum:0, maximum 10] at 15 minutes. Lower values indicate worst outcomes while higher values indicate better outcomes. (NCT02306759)
Timeframe: 15 minutes after administration of study intervention
| Intervention | units on a scale (Median) |
|---|---|
| Treatment | 3.5 |
| Placebo | 6.0 |
ED Length of stay (minutes) throughout study period (NCT02306759)
Timeframe: throughout study completion
| Intervention | minutes (Mean) |
|---|---|
| Treatment | 267 |
| Placebo | 292 |
Incidence or number of participants with adverse events. (NCT02306759)
Timeframe: during the study period
| Intervention | participants (Number) |
|---|---|
| Treatment | 2 |
| Placebo | 4 |
Patient satisfaction of pain control based on a Likert Scale at the end of study completion, an average of 90 minutes. Scores reported out of scale of 10, 10 being most satisfied and 1 being least satisfied. (NCT02306759)
Timeframe: At the end of study period
| Intervention | units on a scale (Mean) |
|---|---|
| Treatment | 8.57 |
| Placebo | 6.05 |
(NCT02306759)
Timeframe: at designated intervals during study period (0, 15, 30, 45, 60, 75, 90, 105, 120 minutes)
| Intervention | milligrams (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| T5 | T15 | T30 | T45 | T60 | T75 | T90 | T105 | T120 | |
| Placebo | 0 | 0.14 | 0.28 | 0 | 0.22 | 0 | 0 | 0.42 | 0.42 |
| Treatment | 0 | 0.23 | 0.37 | 0.07 | 0 | 0 | 0.48 | 0.55 | 0 |
Overall rate of feeling of unreality as measured by Side Effects Rating Scale for Dissociative Anesthetics (SERSDA) (NCT02363270)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| IV Push Group | 22 |
| IV Drip Group | 13 |
"Patient-reported pain scores on numerical rating scale (NRS) -11 pain scale (where 0 indicates no pain at all, 10 indicates the most severe pain). Initial group were patients enrolled and randomized in to the study, assessments were taken at the time of enrollment/randomization in to the study (up to 20 min prior to T=0). T = 0 min assessments were conducted at the time of medication administration (study allowed for an up to 20-minute delay in receiving study drug in order to retrieve study drug from secure storage, nursing documentation and patient verification prior to administration)." (NCT02489630)
Timeframe: 20 min pre-medication administration, 0 min, 30 min, 60 min, 90 min, 120 min post medication administration
| Intervention | Units on a scale (1-10) (Mean) | |||||
|---|---|---|---|---|---|---|
| Initial | T = 0 min | T = 30 min | T = 60 min | T = 90 min | T = 120 min | |
| Ketamine | 9.38 | 7.51 | 5.25 | 5.31 | 4.51 | 4.24 |
| Placebo | 9.44 | 8.10 | 2.27 | 6.18 | 6.21 | 5.68 |
Patient-reported score regarding satisfaction with pain control, reported on a 4-point Likert scale (1-4, where 1 is the lowest satisfaction score possible and 4 is the highest satisfaction score possible). No data is reported for T = 0 min, as that assessment was conducted concurrently with initial medication dosing (since patients were at that point receiving their first pain control efforts, they could not yet assess their satisfaction with those efforts). (NCT02489630)
Timeframe: 0 min, 30 min, 60 min, 90 min, 120 min post medication administration
| Intervention | Units on a scale (1-4) (Mean) | |||
|---|---|---|---|---|
| T = 30 min | T = 60 min | T = 90 min | T = 120 min | |
| Ketamine | 2.09 | 2.38 | 2.54 | 2.66 |
| Placebo | 2.27 | 2.33 | 2.38 | 2.52 |
"Average difference in opiate dosage between study arms, calculated in morphine equivalents. Initial indicates at first dose of opioid administration, up to 20 mins prior to study drug administration, and from 0 min to 120 min after study drug administration." (NCT02489630)
Timeframe: 20 mins pre-medication administration, 0 min, 30 min, 60 min, 90 min, 120 min post medication administration
| Intervention | Milligrams of Morphine Equivalent (Mean) | |
|---|---|---|
| Initial Narcotic Dosage | Total Narcotic Dosage | |
| Ketamine | 5.41 | 9.95 |
| Placebo | 5.83 | 12.81 |
"We will compare efficacy as a difference between 2 groups in pain score at 30 minutes post-analgesic administration. The primary outcome is the difference between 2 groups in pain score at 30 minutes.~Pain will be measured via Numeric rating scale from 0 to 10 with 0 being no pain, 5 being moderate pain, and 10 being severe pain" (NCT01835262)
Timeframe: 30 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| Morphine | 3.93 |
| Ketamine Group | 4.07 |
The primary outcome will be the comparative reduction of NRS pain scores between the 2 groups at 30 minutes. The NRS Pain scale ranges from 0 to 10 (0 being no pain at all to 10 being very severe pain; 5 is moderate pain) (NCT02673372)
Timeframe: 30 minutes
| Intervention | score on a scale (Mean) |
|---|---|
| Morphine Group | 4.4 |
| Ketamine Group | 4.2 |
"Frequency of adverse events secondary to ketamine including fatigue, dizziness, nausea, headache, feeling of unreality, changes in hearing or vision, mood changes, generalized discomfort, and hallucinations, changes in vital signs.~Adverse events were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| at 15 min post infusion | at 30 min post infusion | at 60 min post infusion | at 90 min post infusion | at 120 min post infusion | |
| Arm 1: 0.1 mg/kg Ketamine | 2 | 1 | 1 | 1 | 1 |
| Arm 1: 0.2 mg/kg Ketamine | 3 | 2 | 2 | 2 | 0 |
| Arm 1: 0.3 mg/kg Ketamine | 2 | 1 | 0 | 0 | 0 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | |
| Arm 1: 0.3 mg/kg Ketamine | 7.5 | 2 | 6 | 5 | 2 |
| Arm 1: 0.2 mg/kg Ketamine | 8.5 | 6 | 5.75 | 7 | 7 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | Pain score at 120 min | |
| Arm 1: 0.1 mg/kg Ketamine | 9.4 | 5.25 | 5.25 | 5.25 | 4.5 | 4 |
12 reviews available for ketamine and Wounds and Injuries
| Article | Year |
|---|---|
Patterns of Palliation: A Review of Casualties That Received Pain Management Before Reaching Role 2 in Afghanistan.
Topics: Adult; Afghan Campaign 2001-; Afghanistan; Emergency Medical Services; Fentanyl; Humans; Ketamine; M | 2023 |
Ketamine as a Prehospital Analgesic: A Systematic Review.
Topics: Analgesics; Emergency Medical Services; Humans; Ketamine; Pain; Pain Management; Pain Measurement; W | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
When to Pick the Nose: Out-of-Hospital and Emergency Department Intranasal Administration of Medications.
Topics: Administration, Intranasal; Analgesics, Opioid; Conscious Sedation; Dexmedetomidine; Drug Overdose; | 2017 |
Safety of procedural sedation in pregnancy.
Topics: Anesthesia; Emergencies; Female; Fetus; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Piperi | 2013 |
Ketamine as a promising prototype for a new generation of rapid-acting antidepressants.
Topics: Animals; Antidepressive Agents, Second-Generation; Biomarkers; Depression; Excitatory Amino Acid Ant | 2015 |
Induction agents for intubation of the trauma patient.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Anti-Anxiety Agents; Etomidate; Humans; Intubation; Ke | 2009 |
Ketamine as an analgesic in the pre-hospital setting: a systematic review.
Topics: Analgesics; Emergency Medical Services; Humans; Ketamine; Pain; Randomized Controlled Trials as Topi | 2011 |
Ketamine as an analgesic in the pre-hospital setting: a systematic review.
Topics: Analgesics; Emergency Medical Services; Humans; Ketamine; Pain; Randomized Controlled Trials as Topi | 2011 |
Ketamine as an analgesic in the pre-hospital setting: a systematic review.
Topics: Analgesics; Emergency Medical Services; Humans; Ketamine; Pain; Randomized Controlled Trials as Topi | 2011 |
Ketamine as an analgesic in the pre-hospital setting: a systematic review.
Topics: Analgesics; Emergency Medical Services; Humans; Ketamine; Pain; Randomized Controlled Trials as Topi | 2011 |
Ketamine for paediatric sedation/analgesia in the emergency department.
Topics: Analgesia; Analgesics; Child; Conscious Sedation; Emergency Service, Hospital; Humans; Ketamine; Wou | 2004 |
Pain management in the wilderness and operational setting.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Ste | 2005 |
Review of exertional rhabdomyolysis and a case in a rhesus monkey (Macaca mulatta).
Topics: Alanine Transaminase; Animals; Anorexia; Aspartate Aminotransferases; Atropine; Biopsy; Cefazolin; C | 1998 |
Management of acute pain and anxiety in children undergoing procedures in the emergency department.
Topics: Acute Disease; Analgesia; Analgesics; Anesthesia, Local; Anxiety; Child; Child, Hospitalized; Emerge | 2001 |
18 trials available for ketamine and Wounds and Injuries
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients.
Topics: Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics; Double-Blind Method; Female; Hallucina | 2018 |
Long-term pain prevalence and health-related quality of life outcomes for patients enrolled in a ketamine versus morphine for prehospital traumatic pain randomised controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Australia; Emergency Medicine | 2014 |
Efficacy of small doses of ketamine with morphine to decrease procedural pain responses during open wound care.
Topics: Adult; Aged; Analgesics; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; | 2011 |
Procedural sedation with propofol for painful orthopaedic manipulation in the emergency department expedites patient management compared with a midazolam/ketamine regimen: a randomized prospective study.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Confidence Intervals; Conscious Sedatio | 2011 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries.
Topics: Adjuvants, Anesthesia; Analgesics; Bandages; Burns; Child; Child, Preschool; Conscious Sedation; Dru | 2004 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
Management of severe acute pain in emergency settings: ketamine reduces morphine consumption.
Topics: Acute Disease; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2007 |
[Intramuscular ketamine analgesia in emergency patients. II. Clinical study of traumatized patients].
Topics: Adolescent; Adult; Anesthesia; Blood Pressure; Child; Emergencies; Female; Heart Rate; Humans; Injec | 1984 |
Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia.
Topics: Adult; Analgesia; Double-Blind Method; Female; Fentanyl; Humans; Hyperalgesia; Ketamine; Middle Aged | 1994 |
Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo.
Topics: Adult; Alfentanil; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ketamine; Middle Age | 1995 |
The post-operative analgesic effects of ketamine after canine ovariohysterectomy--a comparison between pre- or post-operative administration.
Topics: Analgesia; Anesthetics, Dissociative; Animals; Dogs; Female; Hysterectomy; Ketamine; Ovariectomy; Pa | 2000 |
Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine.
Topics: Administration, Oral; Anxiety; Child; Child, Preschool; Conscious Sedation; Dose-Response Relationsh | 2001 |
Intravenous ketamine plus midazolam is superior to intranasal midazolam for emergency paediatric procedural sedation.
Topics: Administration, Intranasal; Child; Child, Preschool; Conscious Sedation; Drug Therapy, Combination; | 2001 |
A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in children before suturing.
Topics: Administration, Intranasal; Child; Child, Preschool; Conscious Sedation; Dose-Response Relationship, | 2001 |
Ketamine sedation for children in the emergency department.
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Atropine; Child; Child, Preschool; Clinical Protoc | 2001 |
[Intravenous analgesia with ketamine for emergency patients].
Topics: Adolescent; Adult; Aged; Emergencies; Female; Humans; Injections, Intravenous; Ketamine; Male; Middl | 1987 |
[Clinical observation in dissociative ketamine anesthesia].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Cardiac Surgical Procedures; Child; Child, Prescho | 1972 |
55 other studies available for ketamine and Wounds and Injuries
| Article | Year |
|---|---|
Race and Ethnicity and Prehospital Use of Opioid or Ketamine Analgesia in Acute Traumatic Injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; American Indian or Alaska Native; Analgesia; Analgesics, | 2023 |
[Analgesia for trauma patients in emergency medicine].
Topics: Analgesia; Emergency Medical Services; Emergency Medicine; Fentanyl; Humans; Ketamine; Pain; Pain Ma | 2020 |
A multicenter investigation of the hemodynamic effects of induction agents for trauma rapid sequence intubation.
Topics: Adult; Emergency Service, Hospital; Etomidate; Female; Hemodynamics; Humans; Hypnotics and Sedatives | 2021 |
Impact of Ketamine Use on Adjunctive Analgesic and Sedative Medications in Critically Ill Trauma Patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Critical Illness; Dexmedetomidine; Drug Utilization; Female; | 2017 |
Ketamine for military prehospital analgesia and sedation in combat casualties.
Topics: Accreditation; Analgesics; Capnography; Clinical Governance; Dose-Response Relationship, Drug; Emerg | 2018 |
Anesthesia for Trauma Patients.
Topics: Anesthesia; Anesthetics, Dissociative; Blood Transfusion; Humans; Ketamine; Resuscitation; Wounds an | 2018 |
Effects of low-dose IV ketamine on peripheral and central pain from major limb injuries sustained in combat.
Topics: Adolescent; Adult; Analgesics, Opioid; Excitatory Amino Acid Antagonists; Extremities; Humans; Infus | 2013 |
[Prehospital analgesia performed by paramedics: quality in processes and effects under medical supervision].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allied Health Personnel; Anesthetics, Dissociative; Chil | 2014 |
A Triple-Option Analgesia Plan for Tactical Combat Casualty Care: TCCC Guidelines Change 13-04.
Topics: Acetaminophen; Administration, Buccal; Analgesia; Analgesics; Analgesics, Opioid; Fentanyl; Humans; | 2014 |
Rapid sequence induction of anaesthesia via the intraosseous route: a prospective observational study.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Child; Feasibility Studies; Humans; Infusions, | 2015 |
Prehospital analgesia with ketamine for combat wounds: a case series.
Topics: Acute Pain; Amputation, Traumatic; Analgesics; Analgesics, Opioid; Benzodiazepines; Emergency Medica | 2014 |
Ketamine for prehospital trauma analgesia in a low-resource rural trauma system: a retrospective comparative study of ketamine and opioid analgesia in a ten-year cohort in Iraq.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Cohort Studies; Emergency Medical Services; Female | 2015 |
Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review of practice.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Databases, Factu | 2016 |
En Route Use of Analgesics in Nonintubated, Critically Ill Patients Transported by U.S. Air Force Critical Care Air Transport Teams.
Topics: Adult; Aerospace Medicine; Afghan Campaign 2001-; Air Ambulances; Analgesics; Critical Care; Critica | 2016 |
COMPARISON OF INTRAOPERATIVE KETAMINE VS. FENTANYL USE DECREASES POSTOPERATIVE OPIOID REQUIREMENTS IN TRAUMA PATIENTS UNDERGOING CERVICAL SPINE SURGERY.
Topics: Adult; Analgesics, Opioid; Cervical Vertebrae; Female; Fentanyl; Humans; Intraoperative Period; Keta | 2016 |
Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients.
Topics: Adult; Conscious Sedation; Etomidate; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; I | 2017 |
Pre-hospital use of ketamine for analgesia and procedural sedation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Air Ambulances; Analgesics; Conscious Sedation; Emergenc | 2009 |
Pre-hospital use of ketamine in paediatric trauma.
Topics: Adolescent; Analgesics; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Ketamine; | 2009 |
Methylenedioxymethamphetamine-related deaths in Taiwan: 2001-2008.
Topics: Accidents; Adolescent; Adult; Autopsy; Cause of Death; Excitatory Amino Acid Antagonists; Female; Fl | 2009 |
Which drug for rapid sequence intubation?
Topics: Anesthetics, Dissociative; Drug Interactions; Etomidate; Humans; Hypnotics and Sedatives; Intubation | 2010 |
'The Drug of War'--a historical review of the use of Ketamine in military conflicts.
Topics: Anesthesia; Anesthetics, Dissociative; History, 20th Century; History, 21st Century; Humans; Ketamin | 2009 |
Re: induction agents for intubation of the trauma patient.
Topics: Anesthetics, Intravenous; Etomidate; Humans; Intubation; Ketamine; Wounds and Injuries | 2010 |
Morphine after combat injury and post-traumatic stress disorder.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Fentanyl; Humans; Iraq War, 2003-2011; Ketamine; Mid | 2010 |
Sedation of children in the emergency department for short painful procedures compared with theatre, how much does it save? Economic evaluation.
Topics: Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Cost Savings; Emergency Serv | 2011 |
A standardized rapid sequence intubation protocol facilitates airway management in critically injured patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Airway Management; Androstanols; Anesthesia; Anesthetics | 2012 |
Sedation with ketamine for paediatric procedures in the emergency department--a review of 500 cases.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Emergency Servic | 2002 |
Ketamine is a safe, effective, and appropriate technique for emergency department paediatric procedural sedation.
Topics: Analgesics; Child; Conscious Sedation; Emergency Service, Hospital; Humans; Ketamine; United Kingdom | 2004 |
Procedural sedation in paediatric minor procedures: a prospective audit on ketamine use in the emergency department.
Topics: Analgesics; Attitude to Health; Child; Child, Preschool; Conscious Sedation; Emergency Service, Hosp | 2004 |
Ketamine in prehospital care.
Topics: Accidents, Traffic; Adolescent; Adult; Aged; Analgesia; Analgesics; Emergency Medical Services; Fema | 2004 |
Hemodynamic and immune consequences of opiate analgesia after trauma/hemorrhage.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Corticosterone; Epinephrine; Follow-Up Studies; Hemodyn | 2004 |
Earthquake injuries and the use of ketamine for surgical procedures: the Kashmir experience.
Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Child; Child, Preschool; Disasters; Emergency Me | 2006 |
[Treatment of pain and anesthesia in emergency and catastrophe medicine (author's transl)].
Topics: Analgesics, Opioid; Anesthesia, General; Disasters; Emergencies; Humans; Ketamine; Pain; Wounds and | 1981 |
[Ketalar anesthesia in the first-aid stage with the victims of severe injury and traumatic shock].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Child; Female; First Aid; Humans; Ketamine; Male; | 1984 |
[Ketamine anesthesia in traumatology and orthopedics].
Topics: Adolescent; Adult; Anesthesia, General; Child; Child, Preschool; Humans; Ketamine; Middle Aged; Orth | 1984 |
Infusion analgesia for acute war injuries. A comparison of pentazocine and ketamine.
Topics: Adult; Analgesia; Blood Pressure; Cambodia; Female; Humans; Infusions, Parenteral; Ketamine; Male; M | 1984 |
Preliminary trial of ketamine anesthesia in war casualties.
Topics: Adolescent; Adult; Analgesia; Anesthesia; Humans; Ketamine; Male; Military Medicine; Narcotics; Warf | 1982 |
[Anesthesia procedures in catastrophy from the surgical viewpoint].
Topics: Anesthesia, General; Disasters; Humans; Ketamine; Warfare; Wounds and Injuries; Wounds, Gunshot | 1983 |
[Anesthesia problems of the multiply-injured patient].
Topics: Alfaxalone Alfadolone Mixture; Anesthesia; Critical Care; Emergencies; Humans; Ketamine; Preoperativ | 1980 |
Use of ketamine in prolonged entrapment.
Topics: Accidents; Accidents, Traffic; Adult; Analgesia; Female; First Aid; Humans; Injections, Intravenous; | 1994 |
[Analgetic ketamine feasible in ambulance emergency care].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Child; Cognition Disorders; Eme | 1994 |
Clinical perspectives of intravenous ketamine anaesthesia in peafowl (Pavo cristatus).
Topics: Abscess; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Bird Diseases; Birds; Dose-Resp | 1996 |
The NMDA-receptor antagonist ketamine abolishes neuropathic pain after epidural administration in a clinical case.
Topics: Adolescent; Causalgia; Humans; Injections, Epidural; Ketamine; Leg; Male; Pain; Receptors, N-Methyl- | 1998 |
An alternative to "brutacaine": a comparison of low dose intramuscular ketamine with intranasal midazolam in children before suturing.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anti-Anxiety Agents; Child; Child, Preschool; | 1998 |
Short term immobilization in the horse with ketamine CHl and promazine HCl combinations.
Topics: Anesthesia; Animals; Castration; Drug Evaluation; Female; Horse Diseases; Horses; Injections, Intrav | 1978 |
[Dissociative anesthesia with ketamine. Clinical contribution].
Topics: Eye Diseases; Female; Genital Diseases, Female; Humans; Ketamine; Male; Methods; Otorhinolaryngologi | 1977 |
Pulse oximetry during ketamine anaesthesia in war conditions.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Child; Female; Humans; Ketamine; Male; Middle Aged; Oxim | 1991 |
[Effect of ketamine anesthesia on patients with severe trauma at the pre-hospital stage on the course and outcome of shock].
Topics: Adult; Analgesics, Opioid; Anesthesia, Intravenous; Blood Pressure; First Aid; Humans; Ketamine; Mid | 1990 |
Anaesthesia in the field.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Humans; Ketamine; Military Personnel; Warfare; | 1991 |
[Narcosis within the scope of preclinical care].
Topics: Analgesia; Anesthesia, General; Carbon Dioxide; Diazepam; Emergencies; Etomidate; First Aid; Hemodyn | 1985 |
Total intravenous anaesthesia for military surgery. A technique using ketamine, midazolam and vecuronium.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Female; Hemodynamics; Humans; Ketamine; Male; Midazolam; | 1988 |
[Use of sombrevin-ketamine anesthesia in treating patients with severe injuries].
Topics: Adolescent; Adult; Anesthesia, General; Bandages; Hemodynamics; Humans; Intraoperative Period; Ketam | 1988 |
[War anesthesia. A comparison of ketamine-diazepam and thiopental-halothane anesthesia under war conditions].
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Cambodia; Diazepam; Halothane; H | 1988 |
[Combined midazolam-ketamine anesthesia in traumatologic interventions. Patterns of endocrine reactions].
Topics: Anesthesia, General; Energy Metabolism; Hormones; Humans; Ketamine; Midazolam; Radioimmunoassay; Str | 1988 |
[Ketamine in orthopedics and traumatology: indications and limits].
Topics: Adolescent; Anesthesia; Cardiovascular System; Child; Child, Preschool; Fractures, Bone; Humans; Inf | 1972 |
[Preliminary report on the ketamine-diazepam combination in traumatology].
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics; Cyclohexanes; Diazepam; Drug Combinations; | 1972 |