ketamine has been researched along with Vomiting in 88 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
Excerpt | Relevance | Reference |
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"This study was conducted to determine the effect of intramuscular ondansetron on ketamine-associated vomiting in children undergoing procedural sedation." | 9.34 | Does intramuscular ondansetron have an effect on intramuscular ketamine-associated vomiting in children? A prospective, randomized, double blind, controlled study. ( Akbari, H; Davarani, SS; Hossein, F; Nejati, A; Talebian, MT, 2020) |
" This study was conducted to compare the analgesic efficacy of morphine plus ketamine (MK) versus morphine plus placebo (MP) in patients with acute renal colic." | 9.30 | Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial. ( Bozorgi, F; Erfanian Irankar, S; Hosseini, SA; Hosseininejad, SM; Jahanian, F; Moosazadeh, M; Shahbakhti, N, 2019) |
"To describe the use of ketamine in an adult patient in aborting a cyclic vomiting syndrome (CVS) episode." | 9.22 | Ketamine in Refractory Cyclic Vomiting Syndrome: A Case Report and Review of Literature. ( Cheung, F; Doherty, SM; Tatara, AW, 2022) |
" Parents or caregivers should be given more detailed discharge instructions about vomiting and diet considering the relatively long time to resuming a normal diet after ketamine sedation and the fact that KAV often occurred after ED discharge." | 9.16 | Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study. ( Choi, SC; Jeon, WC; Jung, YS; Kim, GW; Lee, JS; Min, YG; Park, EJ, 2012) |
"S(+)-ketamine reduced both postanesthetic shivering and postoperative nausea and vomiting, when administered for postoperative analgosedation." | 9.13 | Postoperative analgosedation with S(+)-ketamine decreases the incidences of postanesthetic shivering and nausea and vomiting after cardiac surgery. ( Beschmann, RB; Boldt, J; Maleck, WH; Mengistu, A; Piper, SN; Röhm, KD, 2008) |
"We investigate the effect of ondansetron on the incidence of vomiting in children who receive intravenous (IV) ketamine for procedural sedation and analgesia in the emergency department (ED)." | 9.13 | Effect of ondansetron on the incidence of vomiting associated with ketamine sedation in children: a double-blind, randomized, placebo-controlled trial. ( Bajaj, L; Langston, WT; Roback, MG; Wathen, JE, 2008) |
"Ketamine is widely used in emergency departments (EDs) to facilitate painful procedures; however, existing descriptors of predictors of emesis and recovery agitation are derived from relatively small studies." | 8.85 | Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children. ( Agrawal, D; Brown, L; Garcia Pena, BM; Gerber, AC; Green, SM; Hostetler, MA; Krauss, B; Losek, JD; McGlone, RG; McKee, M; Pitetti, RD; Roback, MG; Treston, G; Wathen, JE; Weiss, M, 2009) |
"The xylazine/ketamine anesthesia test is widely used as a predictor of the emetic potential of pharmacological compounds in rats." | 7.91 | Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats. ( Bonassoli, VT; Heckman, PRA; Nelissen, E; Prickaerts, J; Suay, D; van Goethem, NP; van Hagen, BTJ; Wouters, C, 2019) |
"Emesis is one of the most common adverse events associated with ketamine sedation." | 7.85 | Predictors of emesis in children undergoing procedural sedation with intramuscular ketamine in a paediatric emergency department. ( Suryaprakash, S; Tham, LP, 2017) |
"The objective of this study was to determine if overweight children are more likely than normal-weight children to require ondansetron when undergoing ketamine sedation in a pediatric emergency department." | 7.78 | Do children with high body mass indices have a higher incidence of emesis when undergoing ketamine sedation? ( Gerard, JM; Kinder, KL; Lehman-Huskamp, KL, 2012) |
"Within a wide range of intravenous doses, ketamine-associated vomiting is not related to either the initial loading dose or the total dose--except for a modest increase for those receiving high cumulative doses (>7 mg/kg)." | 7.75 | Ketamine-associated vomiting: is it dose-related? ( Brown, L; Green, SM; Thorp, AW, 2009) |
" The incidence of nausea, vomiting, and pruritus was not significantly different in all three groups, although all patients who received ketamine experienced drowsiness after surgery (p<0." | 5.41 | Comparison of Intravenous Ketamine with Intrathecal Meperidine in Prevention of Post-anesthetic Shivering after Spinal Anesthesia for Lower Limb Orthopedic Surgeries: A Double-blind Randomized Clinical Trial. ( Baradari, AG; Gholinataj, A; Kiabi, FH; Najafi, S, 2021) |
"The objective of this study was to determine the association between recent administration of oral analgesics and frequency of adverse events during ketamine sedation in pediatric patients undergoing fracture reduction in the emergency department (ED)." | 5.35 | Oral analgesia before pediatric ketamine sedation is not associated with an increased risk of emesis and other adverse events. ( Kanegaye, JT; McKee, MR; Sharieff, GQ; Stebel, M, 2008) |
"This study was conducted to determine the effect of intramuscular ondansetron on ketamine-associated vomiting in children undergoing procedural sedation." | 5.34 | Does intramuscular ondansetron have an effect on intramuscular ketamine-associated vomiting in children? A prospective, randomized, double blind, controlled study. ( Akbari, H; Davarani, SS; Hossein, F; Nejati, A; Talebian, MT, 2020) |
" This study was conducted to compare the analgesic efficacy of morphine plus ketamine (MK) versus morphine plus placebo (MP) in patients with acute renal colic." | 5.30 | Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial. ( Bozorgi, F; Erfanian Irankar, S; Hosseini, SA; Hosseininejad, SM; Jahanian, F; Moosazadeh, M; Shahbakhti, N, 2019) |
"To describe the use of ketamine in an adult patient in aborting a cyclic vomiting syndrome (CVS) episode." | 5.22 | Ketamine in Refractory Cyclic Vomiting Syndrome: A Case Report and Review of Literature. ( Cheung, F; Doherty, SM; Tatara, AW, 2022) |
" Parents or caregivers should be given more detailed discharge instructions about vomiting and diet considering the relatively long time to resuming a normal diet after ketamine sedation and the fact that KAV often occurred after ED discharge." | 5.16 | Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study. ( Choi, SC; Jeon, WC; Jung, YS; Kim, GW; Lee, JS; Min, YG; Park, EJ, 2012) |
"S(+)-ketamine reduced both postanesthetic shivering and postoperative nausea and vomiting, when administered for postoperative analgosedation." | 5.13 | Postoperative analgosedation with S(+)-ketamine decreases the incidences of postanesthetic shivering and nausea and vomiting after cardiac surgery. ( Beschmann, RB; Boldt, J; Maleck, WH; Mengistu, A; Piper, SN; Röhm, KD, 2008) |
"We investigate the effect of ondansetron on the incidence of vomiting in children who receive intravenous (IV) ketamine for procedural sedation and analgesia in the emergency department (ED)." | 5.13 | Effect of ondansetron on the incidence of vomiting associated with ketamine sedation in children: a double-blind, randomized, placebo-controlled trial. ( Bajaj, L; Langston, WT; Roback, MG; Wathen, JE, 2008) |
"This study compared the incidence of vomiting and the sedative effectiveness of ketamine to a ketamine-prornethazine combination in pediatric dental patients." | 5.10 | A comparison study between ketamine and ketamine-promethazine combination for oral sedation in pediatric dental patients. ( Bui, T; Murphy, S; Redden, RJ, 2002) |
" Apnea occurred in 1 cat treated with methotrimeprazine, romifidine, and ketamine, suggesting that ventilatory support may be necessary when this protocol is used." | 5.09 | A preliminary trial comparison of several anesthetic techniques in cats. ( Cruz, ML; de Castro, GB; Luna, SP; Massone, F; Rosa, AL, 2000) |
" Despite ondansetron and droperidol prophylaxis, there was still a substantial amount of nausea and vomiting after desflurane." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
"Ketamine is widely used in emergency departments (EDs) to facilitate painful procedures; however, existing descriptors of predictors of emesis and recovery agitation are derived from relatively small studies." | 4.85 | Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children. ( Agrawal, D; Brown, L; Garcia Pena, BM; Gerber, AC; Green, SM; Hostetler, MA; Krauss, B; Losek, JD; McGlone, RG; McKee, M; Pitetti, RD; Roback, MG; Treston, G; Wathen, JE; Weiss, M, 2009) |
"The xylazine/ketamine anesthesia test is widely used as a predictor of the emetic potential of pharmacological compounds in rats." | 3.91 | Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats. ( Bonassoli, VT; Heckman, PRA; Nelissen, E; Prickaerts, J; Suay, D; van Goethem, NP; van Hagen, BTJ; Wouters, C, 2019) |
"Emesis is one of the most common adverse events associated with ketamine sedation." | 3.85 | Predictors of emesis in children undergoing procedural sedation with intramuscular ketamine in a paediatric emergency department. ( Suryaprakash, S; Tham, LP, 2017) |
"Midazolam and ketamine were administered consecutively by intravenous route under cardiorespiratory monitoring for painful procedures of pediatric hematology." | 3.81 | The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology. ( Çakmak, E; Demirsoy, U; Gelen, SA; Sarper, N; Zengin, E, 2015) |
"Children who received oral contrast up to 58 minutes before ketamine sedation had a higher rate of vomiting than those who did not receive oral contrast." | 3.81 | Ketamine Sedation After Administration of Oral Contrast: A Retrospective Cohort Study. ( Braun, JL; Lichenstein, R; Teshome, G, 2015) |
"The objective of this study was to determine if overweight children are more likely than normal-weight children to require ondansetron when undergoing ketamine sedation in a pediatric emergency department." | 3.78 | Do children with high body mass indices have a higher incidence of emesis when undergoing ketamine sedation? ( Gerard, JM; Kinder, KL; Lehman-Huskamp, KL, 2012) |
"We conducted a prospective observational study of postdischarge behavioral changes and vomiting after sedation with ketamine, ketamine/midazolam, or fentanyl/midazolam." | 3.75 | Procedural sedation and analgesia outcomes in children after discharge from the emergency department: ketamine versus fentanyl/midazolam. ( Kaye, E; Kido, MM; Krauss, B; McQueen, A; Wright, RO, 2009) |
"Within a wide range of intravenous doses, ketamine-associated vomiting is not related to either the initial loading dose or the total dose--except for a modest increase for those receiving high cumulative doses (>7 mg/kg)." | 3.75 | Ketamine-associated vomiting: is it dose-related? ( Brown, L; Green, SM; Thorp, AW, 2009) |
" Patients receiving ketamine with or without midazolam experienced fewer respiratory adverse events but more vomiting than the commonly used combination of midazolam and fentanyl." | 3.73 | Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs. ( Bajaj, L; Bothner, JP; Roback, MG; Wathen, JE, 2005) |
"To evaluate accident and emergency (A&E) department led practice of ketamine sedation for painful, short procedures in the paediatric population and to ascertain parental response." | 3.70 | Accident and emergency department led implementation of ketamine sedation in paediatric practice and parental response. ( Gautam, V; Holloway, VJ; Husain, HM; Saetta, JP, 2000) |
"We report difficulty with conscious sedation of a child taking methylphenidate for attention deficit disorder and possible delayed adverse interaction of ketamine and methylphenidate resulting in severe nausea, vomiting and dehydration." | 3.69 | Unexpected interaction of methylphenidate (Ritalin) with anaesthetic agents. ( Fox, L; Ririe, DG; Ririe, KL; Sethna, NF, 1997) |
" The efficacy and safety of the sedations including sedation time intervals, nausea score, vomiting episodes, pain score, adverse effects, and parent's satisfaction were evaluated." | 3.11 | The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial. ( Lertvivatpong, N; Malaithong, W; Monsereenusorn, C; Photia, A; Rujkijyanont, P; Traivaree, C, 2022) |
"Postoperative pain was rated at 0, 3, 6, 12, 24, and 48 h postoperatively by visual analogue scale scores (VAS)." | 2.70 | Preincisional intravenous low-dose ketamine and local infiltration with ropivacaine reduces postoperative pain after laparoscopic cholecystectomy. ( Argiriadou, H; Georgiou, M; Papagiannopoulou, P; Papaziogas, B; Papaziogas, T; Pavlidis, T; Sfyra, E, 2001) |
"Hypoxemia was rare except in the propofol group (15." | 2.68 | Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures. ( Barst, SM; McDowall, RH; Scher, CS, 1995) |
"Vomiting was the most common adverse effect (35/1579 [2." | 2.58 | Intranasal ketamine for anesthetic premedication in children: a systematic review. ( Ali, S; Canton, K; Hartling, L; Hendrikx, S; Joubert, G; Miller, M; Poonai, N; Shah, A, 2018) |
"Serious adverse respiratory events are very rare in paediatric procedural sedation in the ED." | 2.53 | Incidence of adverse events in paediatric procedural sedation in the emergency department: a systematic review and meta-analysis. ( Anderson, JL; Barrionuevo, P; Bellolio, MF; Erwin, PJ; Gilani, WI; Hess, EP; Murad, MH; Puls, HA; Wang, Z, 2016) |
" It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia." | 2.48 | Ketamine, propofol, and ketofol use for pediatric sedation. ( Alletag, MJ; Auerbach, MA; Baum, CR, 2012) |
"We review PPS, cardiac tamponade, and the proper performance of a pericardiocentesis." | 2.42 | Cardiac tamponade complicating postpericardiotomy syndrome. ( Alessandrini, EA; Donoghue, AJ; Scarfone, RJ, 2003) |
"Pre- and intraprocedural opioids do not increase the likelihood of sedation-related adverse events." | 1.72 | Opioids Safety in Pediatric Procedural Sedation with Ketamine. ( Cohen, N; Finkelstein, Y; Pasternak, Y; Ratnapalan, S; Schneeweiss, S; Schuh, S; Singer-Harel, D; Test, G, 2022) |
"Ketamine is a medication mainly used for starting and maintaining anesthesia." | 1.48 | Development and validation of an HPLC-MS/MS method for the detection of ketamine in Calliphora vomitoria (L.) (Diptera: Calliphoridae). ( Dadour, IR; Droghi, J; Magni, PA; Pazzi, M; Vincenti, M, 2018) |
"To quantify clinically significant hypersalivation and other adverse events requiring intervention, with and without the use of atropine during ketamine use, using a consensus-based, standardised terminology." | 1.39 | Is prophylactic atropine necessary during ketamine sedation in children? ( Ang, AS; Chew, SP; Chong, JH, 2013) |
" Studying its effects in clinics can be expected to increase our knowledge necessary for the development of new, effective, and safe "antineuralgic drug." | 1.35 | Side effects of ketamine in the long-term treatment of neuropathic pain. ( Cvrcek, P, 2008) |
"The objective of this study was to determine the association between recent administration of oral analgesics and frequency of adverse events during ketamine sedation in pediatric patients undergoing fracture reduction in the emergency department (ED)." | 1.35 | Oral analgesia before pediatric ketamine sedation is not associated with an increased risk of emesis and other adverse events. ( Kanegaye, JT; McKee, MR; Sharieff, GQ; Stebel, M, 2008) |
" We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
"Xylazine and ketamine was administered simultaneously via intratesticularly (IT group), intramuscularly (IM group) or intravenously (IV group) at doses of 2 and 10 mg/kg, respectively." | 1.32 | Effect of intratesticular injection of xylazine/ketamine combination on canine castration. ( Jeong, MB; Jeong, SM; Kim, JK; Lee, ES; Nam, TC; Seo, KM; Yi, NY, 2004) |
"Ketamine is a safe and effective sedative for emergency department procedures in children." | 1.31 | Predictors of adverse events with intramuscular ketamine sedation in children. ( Green, SM; Ho, M; Hummel, CB; Kuppermann, N; Rothrock, SG, 2000) |
"Ketamine hydrochloride was administered intravenously (at a dose of two milligrams per kilogram of body weight) in ninety-nine of the patients and intramuscularly (at a dose of four milligrams per kilogram of body weight) in the other fifteen." | 1.31 | Ketamine sedation for the reduction of children's fractures in the emergency department. ( Green, NE; McCarty, EC; Mencio, GA; Walker, LA, 2000) |
"Emesis was characterized by expulsion of solid or liquid material." | 1.29 | Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents. ( Göthert, M; Herold, H; Szelenyi, I, 1994) |
"Vomiting was produced by the xylazine in 36 cats." | 1.26 | Clinical observations on xylazine/ketamine anaesthesia in the cat. ( Cullen, LK; Jones, RS, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 31 (35.23) | 18.7374 |
1990's | 8 (9.09) | 18.2507 |
2000's | 22 (25.00) | 29.6817 |
2010's | 17 (19.32) | 24.3611 |
2020's | 10 (11.36) | 2.80 |
Authors | Studies |
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Cohen, N | 1 |
Test, G | 1 |
Pasternak, Y | 1 |
Singer-Harel, D | 1 |
Schneeweiss, S | 1 |
Ratnapalan, S | 1 |
Schuh, S | 1 |
Finkelstein, Y | 1 |
Cortellazzo Wiel, L | 1 |
Monasta, L | 1 |
Pascolo, P | 1 |
Servidio, AG | 1 |
Levantino, L | 1 |
Fasoli, S | 1 |
Saccari, A | 1 |
Cozzi, G | 1 |
Barbi, E | 1 |
Gholinataj, A | 1 |
Baradari, AG | 1 |
Najafi, S | 1 |
Kiabi, FH | 1 |
Monsereenusorn, C | 1 |
Malaithong, W | 1 |
Lertvivatpong, N | 1 |
Photia, A | 1 |
Rujkijyanont, P | 1 |
Traivaree, C | 1 |
Zhang, G | 1 |
Li, Q | 1 |
Wang, P | 1 |
Chaghazardi, S | 1 |
Hedari, M | 1 |
Bazargan-Hejazi, S | 1 |
Mohammadi, R | 1 |
Ahmadi, A | 1 |
Nejati, A | 1 |
Davarani, SS | 1 |
Talebian, MT | 1 |
Hossein, F | 1 |
Akbari, H | 1 |
Kuga, S | 1 |
Maeda, T | 1 |
Ihara, K | 1 |
Ben-Yakov, M | 1 |
Bhatt, M | 1 |
Cheung, F | 1 |
Doherty, SM | 1 |
Tatara, AW | 1 |
Liu, SYW | 1 |
Ng, SKK | 1 |
Tam, YH | 1 |
Yee, SCH | 1 |
Lai, FPT | 1 |
Hong, CYL | 1 |
Chiu, PWY | 1 |
Ng, EKW | 1 |
Ng, CF | 1 |
Zhang, M | 1 |
Cowan, T | 1 |
Smiles, JP | 1 |
Morgan, M | 1 |
Armstrong, J | 1 |
Goswami, C | 1 |
Sewell, C | 1 |
Chumpitazi, CE | 1 |
Camp, EA | 1 |
Bhamidipati, DR | 1 |
Montillo, AM | 1 |
Chantal Caviness, A | 1 |
Mayorquin, L | 1 |
Pereira, FA | 1 |
Magni, PA | 1 |
Pazzi, M | 1 |
Droghi, J | 1 |
Vincenti, M | 1 |
Dadour, IR | 1 |
Dunlop, L | 1 |
Hall, D | 1 |
Hosseininejad, SM | 1 |
Jahanian, F | 1 |
Erfanian Irankar, S | 1 |
Moosazadeh, M | 1 |
Hosseini, SA | 1 |
Shahbakhti, N | 1 |
Bozorgi, F | 1 |
Poonai, N | 1 |
Canton, K | 1 |
Ali, S | 1 |
Hendrikx, S | 1 |
Shah, A | 1 |
Miller, M | 1 |
Joubert, G | 1 |
Hartling, L | 1 |
Nelissen, E | 1 |
van Goethem, NP | 1 |
Bonassoli, VT | 1 |
Heckman, PRA | 1 |
van Hagen, BTJ | 1 |
Suay, D | 1 |
Wouters, C | 1 |
Prickaerts, J | 1 |
Chong, JH | 1 |
Chew, SP | 1 |
Ang, AS | 1 |
Lee, JS | 2 |
Jeon, WC | 2 |
Park, EJ | 2 |
Min, YG | 2 |
Kim, GW | 2 |
Jung, YS | 2 |
Choi, SC | 2 |
Gelen, SA | 1 |
Sarper, N | 1 |
Demirsoy, U | 1 |
Zengin, E | 1 |
Çakmak, E | 1 |
Teshome, G | 1 |
Braun, JL | 1 |
Lichenstein, R | 1 |
Bellolio, MF | 1 |
Puls, HA | 1 |
Anderson, JL | 1 |
Gilani, WI | 1 |
Murad, MH | 1 |
Barrionuevo, P | 1 |
Erwin, PJ | 1 |
Wang, Z | 1 |
Hess, EP | 1 |
Suryaprakash, S | 1 |
Tham, LP | 1 |
Dilli, D | 1 |
Dallar, Y | 1 |
Sorgui, NH | 1 |
Piper, SN | 1 |
Beschmann, RB | 1 |
Mengistu, A | 1 |
Maleck, WH | 1 |
Boldt, J | 1 |
Röhm, KD | 1 |
Thorp, AW | 1 |
Brown, L | 2 |
Green, SM | 3 |
McQueen, A | 1 |
Wright, RO | 1 |
Kido, MM | 1 |
Kaye, E | 1 |
Krauss, B | 3 |
Roback, MG | 3 |
McGlone, RG | 1 |
Agrawal, D | 2 |
McKee, M | 1 |
Weiss, M | 1 |
Pitetti, RD | 1 |
Hostetler, MA | 1 |
Wathen, JE | 3 |
Treston, G | 1 |
Garcia Pena, BM | 1 |
Gerber, AC | 1 |
Losek, JD | 1 |
Kinder, KL | 1 |
Lehman-Huskamp, KL | 1 |
Gerard, JM | 1 |
Alletag, MJ | 1 |
Auerbach, MA | 1 |
Baum, CR | 1 |
Betemariam, K | 1 |
Bui, T | 1 |
Redden, RJ | 1 |
Murphy, S | 1 |
Scarfone, RJ | 1 |
Donoghue, AJ | 1 |
Alessandrini, EA | 1 |
Manzi, SF | 1 |
Gupta, R | 1 |
Kim, JK | 1 |
Jeong, SM | 1 |
Yi, NY | 1 |
Jeong, MB | 1 |
Lee, ES | 1 |
Nam, TC | 1 |
Seo, KM | 1 |
Bajaj, L | 2 |
Bothner, JP | 1 |
Bleiberg, AH | 1 |
Salvaggio, CA | 1 |
Roy, LC | 1 |
Kassutto, Z | 1 |
Munro, A | 1 |
Machonochie, I | 1 |
Cvrcek, P | 1 |
McKee, MR | 1 |
Sharieff, GQ | 1 |
Kanegaye, JT | 1 |
Stebel, M | 1 |
Langston, WT | 1 |
Sanders, B | 1 |
Lankenau, SE | 1 |
Bloom, JJ | 1 |
Hathazi, D | 1 |
Barclay, A | 1 |
Houlton, PC | 1 |
Downing, JW | 2 |
Shpilenia, LS | 1 |
Geist, ET | 1 |
Gross, BD | 1 |
Adesiyun, AA | 1 |
Tatini, SR | 1 |
McDowall, RH | 1 |
Scher, CS | 1 |
Barst, SM | 1 |
Szelenyi, I | 1 |
Herold, H | 1 |
Göthert, M | 1 |
Lauretti, GR | 1 |
Azevedo, VM | 1 |
Ririe, DG | 1 |
Ririe, KL | 1 |
Sethna, NF | 1 |
Fox, L | 1 |
Diaz, JH | 1 |
Raeder, JC | 1 |
Mjåland, O | 1 |
Aasbø, V | 1 |
Grøgaard, B | 1 |
Buanes, T | 1 |
Chia, YY | 2 |
Liu, K | 2 |
Liu, YC | 1 |
Chang, HC | 1 |
Wong, CS | 1 |
Kuppermann, N | 1 |
Rothrock, SG | 1 |
Hummel, CB | 1 |
Ho, M | 1 |
Holloway, VJ | 1 |
Husain, HM | 1 |
Saetta, JP | 1 |
Gautam, V | 1 |
Tan, PH | 1 |
Kuo, MC | 1 |
Kao, PF | 1 |
Cruz, ML | 1 |
Luna, SP | 1 |
de Castro, GB | 1 |
Massone, F | 1 |
Rosa, AL | 1 |
McCarty, EC | 1 |
Mencio, GA | 1 |
Walker, LA | 1 |
Green, NE | 1 |
Papaziogas, B | 1 |
Argiriadou, H | 1 |
Papagiannopoulou, P | 1 |
Pavlidis, T | 1 |
Georgiou, M | 1 |
Sfyra, E | 1 |
Papaziogas, T | 1 |
Sportelli, S | 1 |
Zocco, C | 1 |
Margaria, E | 1 |
Lovera, C | 1 |
Saarnivaara, L | 1 |
Cullen, LK | 1 |
Jones, RS | 1 |
Stewart, JJ | 1 |
Burks, TF | 1 |
Weisbrodt, NW | 1 |
Elliott, E | 1 |
Hanid, TK | 1 |
Arthur, LJ | 1 |
Kay, B | 1 |
Dundee, JW | 2 |
Bovill, J | 1 |
Spoerel, WE | 1 |
Board, AJ | 1 |
Henry, RA | 1 |
Little, B | 1 |
Chang, T | 1 |
Chucot, L | 1 |
Dill, WA | 1 |
Enrile, LL | 1 |
Glazko, AJ | 1 |
Jassani, M | 1 |
Kretchmer, H | 1 |
Sweet, AY | 1 |
Sage, M | 1 |
Laird, SM | 1 |
Wakisaka, K | 2 |
Inagaki, M | 2 |
Saito, T | 2 |
Meer, FM | 1 |
Coleman, AJ | 1 |
Loers, JF | 1 |
Hohmann, G | 1 |
Magbagbeola, JA | 1 |
Thomas, NA | 1 |
Collier, BB | 1 |
Wellech, Y | 1 |
Levy, E | 1 |
Wins, M | 1 |
Kramer, RJ | 1 |
Roper, AL | 1 |
Dillon, JB | 1 |
Dalsgård, M | 1 |
Thorshauge, C | 1 |
Weisman, H | 1 |
Brown, TC | 1 |
Cole, WH | 1 |
Murray, GH | 1 |
Knox, JW | 1 |
Bovill, JG | 1 |
Clarke, RS | 1 |
Zook, EG | 1 |
Roesch, RP | 1 |
Thompson, LW | 1 |
Bennett, JE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine[NCT04746079] | 180 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | |||
Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation[NCT03255824] | Phase 4 | 144 participants (Actual) | Interventional | 2018-03-20 | Completed | ||
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139] | Phase 3 | 183 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
US Guided Interscalene Block Compared With Sedation for Shoulder Dislocation Reduction in the ER[NCT03041506] | 90 participants (Anticipated) | Interventional | 2017-02-15 | Not yet recruiting | |||
The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women: Quantification of Ketamine and Metabolites[NCT04285684] | Early Phase 1 | 4 participants (Actual) | Interventional | 2019-12-20 | Completed | ||
Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417] | Phase 2 | 120 participants (Anticipated) | Interventional | 2022-05-01 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Surgeon satisfaction is measured by the Cooperation Scale. Minimum score of 0 and maximum of 9. Higher indicates a worse outcome (i.e., discomfort and movement) (NCT03255824)
Timeframe: 15 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 2.07 |
Dexmedetomidine Group | 1.47 |
"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline by 20% or greater will be considered clinically significant)~a. Change in blood pressure (NIBP) (change ≥ 20%) Blood pressure is presented as mean arterial pressure" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | mm Hg (Mean) |
---|---|
Propofol Group | 78 |
Dexmedetomidine Group | 88 |
"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline of both the blood pressure and heart rate by 20% or greater will be considered clinically significant)~a. Change in heart rate (change ≥ 20 BPM)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | beats per minute (Mean) |
---|---|
Propofol Group | 77 |
Dexmedetomidine Group | 62 |
"Visual Analog Scale was used to measure overall satisfaction with the IV sedation and memory of the procedure.~The minimum score is 0 (not satisfied at all) to a maximum score of 100 (completely satisfied).~A higher score is a better outcome." (NCT03255824)
Timeframe: 30 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 93.5 |
Dexmedetomidine Group | 86.6 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to ambulation (to recovery room) will be recorded" (NCT03255824)
Timeframe: After the procedure until ambulation, up to 20 minutes
Intervention | minutes (Mean) |
---|---|
Propofol Group | 10.8 |
Dexmedetomidine Group | 11.6 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Duration of procedure will be recorded" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | MINUTES (Mean) |
---|---|
Propofol Group | 24.2 |
Dexmedetomidine Group | 22.1 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to discharge or virtual discharge (comparative statistic) - Aldrete score of ≥ 9 or pre-procedure score is met The minimum score is 0 and the maximum score is 10. A higher score indicates wakefulness, hemodynamically stable, and able to ambulate.~ii. All subjects are required to stay a minimum of 30 minutes after the end of the procedure. Therefore, at least two postoperative vital sign readings will be obtained. If the subject meets discharge criteria prior to 30 minutes, this time will be the virtual discharge time" (NCT03255824)
Timeframe: After the procedure until discharge, up to 45 minutes
Intervention | minutes (Mean) |
---|---|
Propofol Group | 26.5 |
Dexmedetomidine Group | 29.9 |
"To compare the groups regarding movement of the patient during the first injection of local anesthesia during the IVS at time of injection measured using the Behavioral Pain Scale - Non-Intubated patients.~The minimum value is 3 and the maximum value is 12. Higher scores mean a worse outcome (i.e., more pain and movement on injection)" (NCT03255824)
Timeframe: During the first injection of local anesthesia during surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 3.9 |
Dexmedetomidine Group | 4.2 |
"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in arterial oxygen saturation (as measured by pulse oximeter) i. number of events of ≤92%" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | Saturation percent (Mean) |
---|---|
Propofol Group | 98.7 |
Dexmedetomidine Group | 98.9 |
"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in respiratory rate (change ≥ 20%)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | breaths per minute (Mean) |
---|---|
Propofol Group | 18 |
Dexmedetomidine Group | 18 |
To compare the groups regarding the number of respiratory events requiring intervention, described as: Chin lift/jaw thrust, Tongue thrust, Yankauer suctioning, Positive pressure oxygen administration, Placement of an oral or nasal airway. (NCT03255824)
Timeframe: During surgery
Intervention | Participants (Count of Participants) |
---|---|
Propofol Group | 17 |
Dexmedetomidine Group | 2 |
"Surgeon satisfaction was measured by the surgeon grading the Operating Conditions scale.~The minimum value was 0 and the maximum was 3. 0=very poor, 1=poor, 2=fair, 3=good" (NCT03255824)
Timeframe: 15 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 2.8 |
Dexmedetomidine Group | 2.9 |
"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | participants (Number) |
---|---|
Ketamine Alone | 97 |
Ketamine Co-Administered With Propofol | 81 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 8 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (1-10) (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 10 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 9 |
Ketamine Co-Administered With Propofol | 8 |
Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour
Intervention | minutes (Median) |
---|---|
Ketamine Alone | 44 |
Ketamine Co-Administered With Propofol | 43.5 |
We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days
Intervention | participants (Number) | |||
---|---|---|---|---|
Respiratory depression | Cardiovascular event | vomiting/retching | Unpleasant recovery reaction | |
Ketamine Alone | 12 | 1 | 21 | 4 |
Ketamine Co-Administered With Propofol | 15 | 0 | 18 | 2 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 24 and 30 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 24 and 30 hour collections
Intervention | ng/mL (Mean) | |
---|---|---|
24 Hours | 30 Hours | |
Ketamine During Lactation | .3 | .3 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | .56 | .55 | .45 | .21 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 2.0 | 1.9 | 1.4 | 1.1 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 24 and 30 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 24 and 30 hour collections
Intervention | ng/mL (Mean) | |
---|---|---|
24 Hours | 30 Hours | |
Ketamine During Lactation | 30.5 | 13.9 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 29.9 | 28.3 | 25.6 | 17.5 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 64.1 | 66.9 | 54.6 | 41.6 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 24 and 30 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 24 and 30 hour collections
Intervention | ng/mL (Mean) | |
---|---|---|
24 Hours | 30 Hours | |
Ketamine During Lactation | 4.9 | 6.4 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 51.2 | 22.6 | 10.6 | 4.5 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 125.0 | 48.2 | 21.6 | 18.5 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 24 and 30 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 24 and 30 hour collections
Intervention | ng/mL (Mean) | |
---|---|---|
24 Hours | 30 Hours | |
Ketamine During Lactation | 10.3 | 9.9 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 42.6 | 28.6 | 18.8 | 8.7 |
"Quantitative analysis of the concentration of ketamine and its metabolites in breast milk (collected by pumping breast milk into containers at 3, 6, 9, and 12 hours post ketamine IM administration) was performed at the Clinical Medicine and Toxicology Laboratory at UCSF School of Medicine. Sample aliquots were frozen in our conventional freezer at the clinic where the sessions took place, labelled with a HIPAA compliant code which blinded the lab to all patient data.~The limits of sensitivity for the quantification of each substance were:~Ketamine: 0.25 ng Norketamine: 0.25 ng Dehydronorketamine: 0.1 ng Hydroxynorketamine: 0.25 ng" (NCT04285684)
Timeframe: 3, 6, 9, and 12 hour collections
Intervention | ng/mL (Mean) | |||
---|---|---|---|---|
3 Hours | 6 Hours | 9 Hours | 12 Hours | |
Ketamine During Lactation | 92.7 | 62.4 | 37.3 | 32.3 |
9 reviews available for ketamine and Vomiting
Article | Year |
---|---|
The analgesic efficacy of ketamine for septorhinoplasty: a meta-analysis study.
Topics: Analgesics; Humans; Ketamine; Pain Management; Pain, Postoperative; Vomiting | 2023 |
Ketamine in Refractory Cyclic Vomiting Syndrome: A Case Report and Review of Literature.
Topics: Adult; Analgesics; Anesthetics; Humans; Hypnotics and Sedatives; Ketamine; Lorazepam; Male; Ondanset | 2022 |
BET 2: Antiemetic use in paediatric sedation with ketamine.
Topics: Anesthetics, Dissociative; Antiemetics; Child; Conscious Sedation; Humans; Ketamine; Vomiting | 2018 |
Intranasal ketamine for anesthetic premedication in children: a systematic review.
Topics: Administration, Intranasal; Adolescent; Adult; Anesthetics, Inhalation; Child; Child, Preschool; Hum | 2018 |
Incidence of adverse events in paediatric procedural sedation in the emergency department: a systematic review and meta-analysis.
Topics: Anesthetics, Dissociative; Child; Conscious Sedation; Drug-Related Side Effects and Adverse Reaction | 2016 |
Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children.
Topics: Age Factors; Anesthesia Recovery Period; Anesthetics, Dissociative; Benzodiazepines; Child; Child, P | 2009 |
Ketamine, propofol, and ketofol use for pediatric sedation.
Topics: Adolescent; Amnesia; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Antiemetics; An | 2012 |
Cardiac tamponade complicating postpericardiotomy syndrome.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Cardiac Tamponade; Child; Child, Preschool; Combined | 2003 |
Midazolam or ketamine for procedural sedation of children in the emergency department.
Topics: Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Emergency Medicine; Humans; | 2007 |
23 trials available for ketamine and Vomiting
Article | Year |
---|---|
Comparison of Intravenous Ketamine with Intrathecal Meperidine in Prevention of Post-anesthetic Shivering after Spinal Anesthesia for Lower Limb Orthopedic Surgeries: A Double-blind Randomized Clinical Trial.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics; Double-Blind Method; Humans; Injections, Spinal | 2021 |
The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial.
Topics: Child; Cross-Over Studies; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Neoplasms | 2022 |
Comparing the Effect of Gabapentin, Ketamine, Dexmedetomidine, and Entonox on Pain Control in Burn Wound Dressing.
Topics: Adult; Analgesics; Bandages; Blood Pressure; Burns; Debridement; Dexmedetomidine; Female; Gabapentin | 2020 |
Does intramuscular ondansetron have an effect on intramuscular ketamine-associated vomiting in children? A prospective, randomized, double blind, controlled study.
Topics: Anesthetics, Dissociative; Antiemetics; Child; Child, Preschool; Closed Fracture Reduction; Consciou | 2020 |
Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial.
Topics: Acute Disease; Adult; Analgesics; Dizziness; Double-Blind Method; Drug Therapy, Combination; Emergen | 2019 |
Does ondansetron have an effect on intramuscular ketamine-associated vomiting in children? A prospective, randomised, open, controlled study.
Topics: Administration, Oral; Adolescent; Anesthetics, Dissociative; Antiemetics; Child; Child, Preschool; D | 2014 |
Intravenous ketamine plus midazolam vs. intravenous ketamine for sedation in lumbar puncture: a randomized controlled trial.
Topics: Adolescent; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Confidence Intervals; Dizzin | 2008 |
Postoperative analgosedation with S(+)-ketamine decreases the incidences of postanesthetic shivering and nausea and vomiting after cardiac surgery.
Topics: Aged; Anesthesia; Case-Control Studies; Coronary Artery Bypass; Female; Humans; Hypnotics and Sedati | 2008 |
Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study.
Topics: Anesthetics, Dissociative; Antiemetics; Atropine; Child, Preschool; Female; Humans; Infant; Ketamine | 2012 |
A comparison study between ketamine and ketamine-promethazine combination for oral sedation in pediatric dental patients.
Topics: Administration, Oral; Anesthesia, Dental; Anesthetics, Dissociative; Anesthetics, Inhalation; Awaren | 2002 |
Effect of ondansetron on the incidence of vomiting associated with ketamine sedation in children: a double-blind, randomized, placebo-controlled trial.
Topics: Adolescent; Anesthetics, Dissociative; Antiemetics; Chi-Square Distribution; Child; Child, Preschool | 2008 |
Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Child; Child, Preschool; Etomid | 1995 |
Intranasal ketamine preinduction of paediatric outpatients.
Topics: Administration, Intranasal; Age Factors; Ambulatory Surgical Procedures; Anesthesia Recovery Period; | 1997 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
Adding ketamine in a multimodal patient-controlled epidural regimen reduces postoperative pain and analgesic consumption.
Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; A | 1998 |
Patient-controlled epidural analgesia with morphine or morphine plus ketamine for post-operative pain relief.
Topics: Abdomen; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Arousal | 1999 |
A preliminary trial comparison of several anesthetic techniques in cats.
Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Apnea; Cats; Drug Therapy, Combination; Fem | 2000 |
Preincisional intravenous low-dose ketamine and local infiltration with ropivacaine reduces postoperative pain after laparoscopic cholecystectomy.
Topics: Adult; Amides; Analgesics; Anesthetics, Local; Cholecystectomy, Laparoscopic; Cholelithiasis; Dose-R | 2001 |
[Intramuscular anesthesia with Ketalar. Our experience in 2446 cases].
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Injections, Intramusc | 1978 |
Comparison of thiopentone, Althesin and ketamine in anaesthesia for otolaryngological surgery in children.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, General; Blood Pressure; Child; Child, Preschool; Female; | 1977 |
Ketamine.
Topics: Analgesics; Anesthetics; Atropine; Clinical Trials as Topic; Cyclohexanes; Delirium; Humans; Hyperte | 1970 |
[Ketamine-dehydrobenzperidol and ketamine-diazepam combinations for anaesthesia in neuro-radiology].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Angiography; Benperidol; Blood Pressure; Brachial | 1973 |
Ketamine and the conscious mind.
Topics: Adolescent; Adult; Aged; Anesthetics; Cannabis; Color Perception; Consciousness; Cyclohexanes; Deper | 1972 |
56 other studies available for ketamine and Vomiting
Article | Year |
---|---|
Opioids Safety in Pediatric Procedural Sedation with Ketamine.
Topics: Analgesics, Opioid; Child; Child, Preschool; Conscious Sedation; Emergency Service, Hospital; Female | 2022 |
Recovery characteristics and parental satisfaction in pediatric procedural sedation.
Topics: Child; Conscious Sedation; Dexmedetomidine; Hallucinations; Humans; Hypnotics and Sedatives; Ketamin | 2022 |
Pediatric procedural sedation in Japan: A single-facility study of 1,436 cases.
Topics: Administration, Intravenous; Adolescent; Child; Child, Preschool; Conscious Sedation; Drug Therapy, | 2020 |
Emergency procedural sedation in children.
Topics: Anesthetics, Dissociative; Antiemetics; Child; Contraindications, Drug; Emergency Service, Hospital; | 2020 |
Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.
Topics: Abdominal Pain; Administration, Inhalation; Adolescent; Adult; Analgesics; Anemia; Case-Control Stud | 2017 |
Prehospital analgesic choice in injured patients does not impact on rates of vomiting: Experience from a New South Wales primary retrieval service.
Topics: Adolescent; Adult; Analgesics; Analgesics, Opioid; Antiemetics; Emergency Medical Services; Female; | 2018 |
Shortened preprocedural fasting in the pediatric emergency department.
Topics: Analgesia; Analgesics; Child; Child, Preschool; Conscious Sedation; Emergency Service, Hospital; Fas | 2018 |
Development and validation of an HPLC-MS/MS method for the detection of ketamine in Calliphora vomitoria (L.) (Diptera: Calliphoridae).
Topics: Anesthetics, Dissociative; Animals; Chromatography, High Pressure Liquid; Diptera; Feeding Behavior; | 2018 |
Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats.
Topics: Anesthesia; Animals; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; | 2019 |
Is prophylactic atropine necessary during ketamine sedation in children?
Topics: Adjuvants, Anesthesia; Adolescent; Anesthetics, Dissociative; Atropine; Child; Child, Preschool; Eme | 2013 |
The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
Topics: Adolescent; Analgesia; Analgesics; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation; | 2015 |
Ketamine Sedation After Administration of Oral Contrast: A Retrospective Cohort Study.
Topics: Administration, Oral; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Contra | 2015 |
Predictors of emesis in children undergoing procedural sedation with intramuscular ketamine in a paediatric emergency department.
Topics: Age Factors; Antiemetics; Asian People; Child; Child, Preschool; Conscious Sedation; Emergency Servi | 2017 |
Ketamine-associated vomiting: is it dose-related?
Topics: Adolescent; Benzodiazepines; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interac | 2009 |
Procedural sedation and analgesia outcomes in children after discharge from the emergency department: ketamine versus fentanyl/midazolam.
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Child; Child Behavior Disorders; Emergency Service | 2009 |
Do children with high body mass indices have a higher incidence of emesis when undergoing ketamine sedation?
Topics: Adolescent; Anesthetics, Dissociative; Antiemetics; Body Mass Index; Child; Child, Preschool; Emerge | 2012 |
Experience in the use of laryngeal mask airway in Tikur Anbessa Hospital.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Dissociative; An | 2002 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
Effect of intratesticular injection of xylazine/ketamine combination on canine castration.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Body Temperature | 2004 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Low-dose ketamine: efficacy in pediatric sedation.
Topics: Adolescent; Atropine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; Dr | 2007 |
Side effects of ketamine in the long-term treatment of neuropathic pain.
Topics: Adolescent; Adult; Analgesics; Diabetic Neuropathies; Drug Administration Schedule; Female; Follow-U | 2008 |
Oral analgesia before pediatric ketamine sedation is not associated with an increased risk of emesis and other adverse events.
Topics: Administration, Oral; Analgesics; Child; Conscious Sedation; Emergency Service, Hospital; Fasting; F | 2008 |
"Research chemicals": tryptamine and phenethylamine use among high-risk youth.
Topics: Adolescent; Adult; California; Catchment Area, Health; Confusion; Cross-Sectional Studies; Diarrhea; | 2008 |
Total intravenous anaesthesia: a technique using flunitrazepam, ketamine, muscle relaxants and controlled ventilation of the lung.
Topics: Adult; Aged; Alcuronium; Anesthesia, Intravenous; Anti-Anxiety Agents; Blood Pressure; Blood Transfu | 1980 |
[Experience with the use of ketamine in psychiatric practice].
Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Ketamine; Male; Nausea; Schi | 1984 |
Reduction of ketamine-induced emergence phenomena by preoperative promethazine.
Topics: Child; Child, Preschool; Double-Blind Method; Hallucinations; Humans; Ketamine; Nausea; Promethazine | 1982 |
Incidence of ketamine-induced emesis in cynomologus monkeys (Macaca fascicularis) used for staphylococcal enterotoxin bioassay.
Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Enterotoxins; Female; Ketamine; Macaca | 1982 |
Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents.
Topics: Animals; Antiemetics; Antineoplastic Agents; Carboplatin; Cisplatin; Cyclophosphamide; Dactinomycin; | 1994 |
Intravenous ketamine or fentanyl prolongs postoperative analgesia after intrathecal neostigmine.
Topics: Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Dissociative; Anesthetics, Intraveno | 1996 |
Unexpected interaction of methylphenidate (Ritalin) with anaesthetic agents.
Topics: Anesthetics, Dissociative; Attention Deficit Disorder with Hyperactivity; Central Nervous System Sti | 1997 |
Predictors of adverse events with intramuscular ketamine sedation in children.
Topics: Adolescent; Age Distribution; Airway Obstruction; Akathisia, Drug-Induced; Analysis of Variance; Ane | 2000 |
Accident and emergency department led implementation of ketamine sedation in paediatric practice and parental response.
Topics: Anesthetics, Dissociative; Attitude to Health; Child; Child, Preschool; Conscious Sedation; Emergenc | 2000 |
Ketamine sedation for the reduction of children's fractures in the emergency department.
Topics: Analgesics; Anesthetics, Dissociative; Ataxia; Blood Pressure; Child; Child, Preschool; Cohort Studi | 2000 |
[Althesin in cesarean section].
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Obstetrical; Barbiturates; Blood Pressure; Cesarea | 1978 |
Clinical observations on xylazine/ketamine anaesthesia in the cat.
Topics: Anesthesia; Animals; Cat Diseases; Cats; Female; Ketamine; Male; Surgical Procedures, Operative; Thi | 1977 |
Intestinal myoelectric activity after activation of central emetic mechanism.
Topics: Action Potentials; Animals; Apomorphine; Cats; Epinephrine; Female; Injections, Intraperitoneal; Inj | 1977 |
Ketamine anaesthesia for medical procedures in children.
Topics: Adolescent; Anesthesia, Intravenous; Atropine; Child; Child, Preschool; Drug Combinations; Female; H | 1976 |
Ketalar (CI-581) in paediatric dentistry: a field trial in three Arctic communities.
Topics: Analgesics; Anesthesia, Dental; Anesthesia, Intravenous; Arctic Regions; Child; Child, Preschool; Cy | 1970 |
Ketamine. The economics of anaesthesia in developing countries.
Topics: Developing Countries; Economics, Medical; Humans; Injections, Intramuscular; Injections, Intravenous | 1974 |
Study of ketamine as an obstetric anesthetic agent.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics; Apgar Score; Bilirubin; Blood Pressure; Carbon Dioxide; | 1972 |
Study of ketamine as an obstetric anesthetic agent.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics; Apgar Score; Bilirubin; Blood Pressure; Carbon Dioxide; | 1972 |
Study of ketamine as an obstetric anesthetic agent.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics; Apgar Score; Bilirubin; Blood Pressure; Carbon Dioxide; | 1972 |
Study of ketamine as an obstetric anesthetic agent.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics; Apgar Score; Bilirubin; Blood Pressure; Carbon Dioxide; | 1972 |
Ketamine and the laryngeal reflex.
Topics: Child; Child, Preschool; Humans; Infant; Injections, Intramuscular; Ketamine; Laryngeal Diseases; Re | 1972 |
[Vomiting after intramuscular ketamine anesthesia].
Topics: Anesthesia; Atropine; Child; Deglutition; Eye Diseases; Humans; Injections, Intramuscular; Ketamine; | 1972 |
An intravenous method of anaesthesia for Caesarean section. II. Ketamine.
Topics: Acid-Base Equilibrium; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apgar Score; Blood Pressure | 1973 |
[Use of ketamine in patients with high risques (author's transl)].
Topics: Adult; Anesthesia; Blood Pressure; Female; Humans; Ketamine; Male; Middle Aged; Vasodilator Agents; | 1973 |
Effect of thiopentone on emergence reactions to ketamine anaesthesia.
Topics: Anesthesia, Intravenous; Anxiety; Dreams; Female; Humans; Infusions, Parenteral; Ketamine; Thiopenta | 1974 |
[Experience with ketamine].
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Child; Child, Preschool; Cyclohexanes; Hallucin | 1972 |
Ketamine anaesthesia.
Topics: Airway Obstruction; Analgesics; Anesthesia, General; Cyanosis; Cyclohexanes; Female; Humans; Infant; | 1971 |
Ketamine anesthesia in minor otologic procedures.
Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood Pressure; Child; Child, | 1971 |
Rational use of ketamine as an anaesthetic.
Topics: Adolescent; Adult; Aged; Anesthetics; Blood Pressure; Cerebrospinal Fluid; Child; Cyclohexanes; Drea | 1971 |
[Experience with Ketalar anesthesia].
Topics: Anesthetics; Blood Pressure; Child; Cyclohexanes; Cyclopropanes; Female; Halothane; Humans; Hyperten | 1971 |
Anesthesia for pediatric ophthalmology.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Dissociative; Arrhythmias, Cardiac; Barbit | 1971 |
Ketamine: A new anaesthetic agent.
Topics: Analgesics; Anesthesia, Intravenous; Anesthetics; Cardiovascular System; Child; Child, Preschool; Cy | 1970 |
[Dream, nausea and vomiting during ketamine anesthesia].
Topics: Adolescent; Adult; Anesthetics; Cyclohexanes; Diazepam; Dreams; Female; Humans; Ketamine; Nausea; Pr | 1970 |
Clinical studies of induction agents. XXXVI: Ketamine.
Topics: Adult; Analgesics; Anesthesia, Intravenous; Anesthetics; Atropine; Attitude to Health; Blood Pressur | 1970 |
Ketamine anesthesia in pediatric plastic surgery.
Topics: Age Factors; Analgesics; Anesthesia, Intravenous; Burns; Child; Child, Preschool; Craniocerebral Tra | 1971 |