Page last updated: 2024-10-29

ketamine and Ventricular Dysfunction, Left

ketamine has been researched along with Ventricular Dysfunction, Left in 6 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Research Excerpts

ExcerptRelevanceReference
"Ketamine appears to be a safe anesthetic option for children with PAH."5.36Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010)
"Using a high-frequency linear transducer (15L8), we studied 1) the feasibility of performing echocardiography in nonanesthetized mice compared with mice given pentobarbital sodium (Pento) or a mixture of ketamine and xylazine and 2) the feasibility of echocardiographic evaluation of left ventricular (LV) hypertrophy, dilatation, and function in mice with two-kidney, one-clip hypertension or myocardial infarction (MI)."3.70Echocardiographic assessment of cardiac function in conscious and anesthetized mice. ( Carretero, OA; Kim, HE; Kurihara, N; Liu, YH; Rhaleb, NE; Yang, XP, 1999)
"Ketamine has a favorable cardiovascular profile related to central sympathetic stimulation and inhibition of neuronal catecholamine uptake."2.43Intravenous anesthesia for the patient with left ventricular dysfunction. ( Bovill, JG, 2006)
"Ketamine appears to be a safe anesthetic option for children with PAH."1.36Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cuijpers, I1
Carai, P1
Mendes-Ferreira, P1
Simmonds, SJ1
Mulder, P1
Miranda-Silva, D1
De Giorgio, D1
Pokreisz, P1
Heymans, S1
Jones, EAV1
de Lima, AD1
Guido, MC1
Tavares, ER1
Carvalho, PO1
Marques, AF1
de Melo, MDT1
Salemi, VMC1
Kalil-Filho, R1
Maranhão, RC1
Lazar, JM1
Qureshi, G1
Qureshi, MR1
Smith, E1
Scharf, B1
Rosenblum, LA1
Signaevsky, M1
Kral, JG1
Salciccioli, L1
Williams, GD1
Maan, H1
Ramamoorthy, C1
Kamra, K1
Bratton, SL1
Bair, E1
Kuan, CC1
Hammer, GB1
Feinstein, JA1
Bovill, JG1
Yang, XP1
Liu, YH1
Rhaleb, NE1
Kurihara, N1
Kim, HE1
Carretero, OA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia: Pretreatment With Low-dose Ketamine Can Reduce the Dose of Etomidate. A Randomized Clinical Trial.[NCT04857450]60 participants (Anticipated)Interventional2020-11-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ketamine and Ventricular Dysfunction, Left

ArticleYear
Intravenous anesthesia for the patient with left ventricular dysfunction.
    Seminars in cardiothoracic and vascular anesthesia, 2006, Volume: 10, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Etomidate; Humans; Ket

2006

Other Studies

5 other studies available for ketamine and Ventricular Dysfunction, Left

ArticleYear
The effect of different anaesthetics on echocardiographic evaluation of diastolic dysfunction in a heart failure with preserved ejection fraction model.
    Scientific reports, 2020, 09-24, Volume: 10, Issue:1

    Topics: Anesthetics; Animals; Diastole; Echocardiography; Heart Failure; Heart Rate; Isoflurane; Ketamine; M

2020
The Expression of Lipoprotein Receptors Is Increased in the Infarcted Area After Myocardial Infarction Induced in Rats With Cardiac Dysfunction.
    Lipids, 2018, Volume: 53, Issue:2

    Topics: Animals; Gene Expression Profiling; Ketamine; Male; Myocardial Infarction; Rats; Rats, Wistar; Recep

2018
Left ventricular systolic and diastolic function in healthy adult bonnet macaques (Macaca radiata). New echocardiographic indices in Old World monkeys.
    Cardiology, 2009, Volume: 113, Issue:2

    Topics: Anesthetics, Dissociative; Animals; Diastole; Disease Models, Animal; Echocardiography; Female; Keta

2009
Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:1

    Topics: Adolescent; Anesthesia, General; Anesthetics, Dissociative; Blood Pressure; Cardiac Surgical Procedu

2010
Echocardiographic assessment of cardiac function in conscious and anesthetized mice.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Dissociative; Animals; Drug Combinations; E

1999