Page last updated: 2024-10-29

ketamine and Urinary Tract Diseases

ketamine has been researched along with Urinary Tract Diseases in 36 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"A 29-year-old male patient with a 3-year history of ketamine inhalation, complaining of dysuria with frequency and urgency, was admitted."7.91Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male. ( Jin, Z; Liao, Z; Tang, Z; Wang, Z, 2019)
"A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse."7.74The destruction of the lower urinary tract by ketamine abuse: a new syndrome? ( Cheng, CH; Chu, PS; Chu, RW; Lau, FL; Ma, WK; Man, CW; Tse, JM; Wong, S; Wong, SC; Yiu, MK, 2008)
"Ketamine has become increasingly recognized as a drug of recreational use."6.47Recreational ketamine: from pleasure to pain. ( Baker, SC; Cottrell, A; Fulford, S; Gillatt, D; Harris, M; Southgate, J; Wood, D; Woodhouse, C, 2011)
"Ketamine is a dissociative anaesthetic agent that is still widely used in veterinary and human medicine."5.37Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series. ( Austin, AS; Freeman, JG; Krishnamoorthy, R; Lo, RS, 2011)
"Ketamine-associated uropathy frequently involves frequency, urgency, and suprapubic pain; upper urinary tract involvement is less common."5.22Systematic review and meta-analysis of ketamine-associated uropathy. ( Chan, EOT; Chan, VWS; Cheung, V; Ng, CF; Tang, TST; Teoh, JYC; Wong, MCS; Yee, CH, 2022)
"A 29-year-old male patient with a 3-year history of ketamine inhalation, complaining of dysuria with frequency and urgency, was admitted."3.91Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male. ( Jin, Z; Liao, Z; Tang, Z; Wang, Z, 2019)
"A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse."3.74The destruction of the lower urinary tract by ketamine abuse: a new syndrome? ( Cheng, CH; Chu, PS; Chu, RW; Lau, FL; Ma, WK; Man, CW; Tse, JM; Wong, S; Wong, SC; Yiu, MK, 2008)
"Ketamine (K) is a good analgesic and anesthetic agent in short procedures, but the associated cardiovascular responses and emergence reactions limit its use."2.67Ketamine anesthesia for short transurethral urologic procedures. ( Attalah, MM; Ibrahiem, EH; Saied, MM; Yahya, R, 1993)
"Ketamine is an N-methyl-d-aspartate receptor antagonist, a dissociative anaesthetic agent and a treatment option for major depression, treatment-resistant depression, and bipolar disorder."2.58Management of complications of ketamine abuse: 10 years' experience in Hong Kong. ( Hong, YL; Lai, PT; Ng, CF; Tam, YH; Wong, JH; Yee, CH, 2018)
"Ketamine is a dissociative anesthetic and substance of abuse."2.50Ketamine: an update on its abuse. ( Anderson, PD; Bokor, G, 2014)
"Urological toxicity, hepatotoxicity and cognitive deficits are all reported as adverse effects of the recreational use of ketamine."2.48Ketamine for chronic noncancer pain: concerns regarding toxicity. ( Bell, RF, 2012)
"Ketamine has become increasingly recognized as a drug of recreational use."2.47Recreational ketamine: from pleasure to pain. ( Baker, SC; Cottrell, A; Fulford, S; Gillatt, D; Harris, M; Southgate, J; Wood, D; Woodhouse, C, 2011)
"Hydronephrosis was present in 20 (24."1.91Ketamine uropathy: Clinical experience in a high prevalence center. ( Beckley, I; Downey, A; Shepherd, R; Sturgess, G, 2023)
"A notice posted on the website invited substance users to participate in a web-based survey on "drug use and health"."1.39Ketamine is associated with lower urinary tract signs and symptoms. ( Baggott, MJ; Balt, S; Erowid, E; Erowid, F; Galloway, GP; Mendelson, J; Pal, R, 2013)
"Ketamine is a dissociative anaesthetic agent that is still widely used in veterinary and human medicine."1.37Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series. ( Austin, AS; Freeman, JG; Krishnamoorthy, R; Lo, RS, 2011)
"Ketamine is a short-acting dissociative anaesthetic whose hallucinogenic side effects have led to an increase in its illicit use amongst club and party goers."1.36Ketamine-associated lower urinary tract destruction: a new radiological challenge. ( Corrigan, AG; Cottrell, AM; Gillatt, DA; Mason, K; Mitchelmore, AE, 2010)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.89)18.7374
1990's3 (8.33)18.2507
2000's2 (5.56)29.6817
2010's23 (63.89)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Chan, EOT3
Chan, VWS3
Tang, TST3
Cheung, V3
Wong, MCS3
Yee, CH5
Ng, CF6
Teoh, JYC3
Sturgess, G1
Beckley, I1
Shepherd, R1
Downey, A1
Liao, Z1
Wang, Z1
Jin, Z1
Tang, Z2
Ou, SH1
Wu, LY1
Chen, HY1
Huang, CW1
Hsu, CY1
Chen, CL1
Chou, KJ1
Fang, HC1
Lee, PT1
Liu, SYW1
Ng, SKK1
Tam, YH3
Yee, SCH1
Lai, FPT1
Hong, CYL1
Chiu, PWY1
Ng, EKW1
Jhang, JF1
Hsu, YH1
Jiang, YH1
Lee, CL1
Kuo, HC1
Hong, YL1
Wong, JH1
Lai, PT1
Pal, R1
Balt, S1
Erowid, E1
Erowid, F1
Baggott, MJ1
Mendelson, J1
Galloway, GP1
Pang, KK1
Chu, WC1
Leung, VY1
Wong, GL1
Wong, VW1
Chan, HL1
Lai, PB1
Bokor, G1
Anderson, PD1
Chu, PS2
Dasgupta, P1
Taylor, CF1
Winstock, AR1
Olsburgh, J1
Zeng, M1
Huang, L1
Li, Y1
Zeng, F1
Xue, R1
Wein, AJ1
Wu, P1
Wang, Q1
Huang, Z1
Wang, J1
Wu, Q1
Lin, T1
Myers, FA1
Bluth, MH1
Cheung, WW1
Ma, WK1
Wong, SC1
Chu, RW1
Cheng, CH1
Wong, S1
Tse, JM1
Lau, FL1
Yiu, MK1
Man, CW1
Storr, TM1
Quibell, R1
Mason, K1
Cottrell, AM1
Corrigan, AG1
Gillatt, DA1
Mitchelmore, AE1
Wood, D1
Cottrell, A1
Baker, SC1
Southgate, J1
Harris, M1
Fulford, S1
Woodhouse, C1
Gillatt, D1
Lo, RS1
Krishnamoorthy, R1
Freeman, JG1
Austin, AS1
Seto, WK1
Ng, M1
Chan, P1
Ng, IO1
Cheung, SC1
Hung, IF1
Yuen, MF1
Lai, CL1
Wu, S1
Lai, Y1
He, Y1
Li, X1
Guan, Z1
Cai, Z1
Forster, JA1
Harrison, SC1
Jansonius, A1
Oddens, JR1
Bell, RF1
Wei, Y1
Yang, J1
Song, W1
Guo, Q1
Thevaraja, AK1
Batra, YK1
Rakesh, SV1
Panda, NB1
Rao, KL1
Chhabra, M1
Aggarwal, M1
Salehi, E1
Attalah, MM1
Saied, MM1
Yahya, R1
Ibrahiem, EH1
Tablov, V2
Stratev, S2
Dukanov, M1
D'Auria, C1
Petrillo, P1
Andrisani, I1
Bruno, V1
Montemurro, D1
Dimitrov, M1
Feins, NR1
Ishida, G1
Ikeda, Y1
Wataru, S1
Takenaka, I1
Sugawara, K1
Homma, A1
Kumamoto, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravesical Injection of Dextrose to Improve Lower Urinary Tract Symptoms Caused by Chronic Cystitis[NCT04821882]29 participants (Actual)Interventional2019-05-01Completed
Prospective Longitudinal Study on the Treatment Outcomes of Various Treatment Modalities Under a Standardized Treatment Protocol in Patients Suffered Substance Abuse Related Voiding Dysfunction[NCT03913819]1,000 participants (Anticipated)Observational2011-12-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for ketamine and Urinary Tract Diseases

ArticleYear
Systematic review and meta-analysis of ketamine-associated uropathy.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2022, Volume: 28, Issue:6

    Topics: Cystitis; Humans; Ketamine; Pain; Urinary Bladder; Urologic Diseases

2022
Systematic review and meta-analysis of ketamine-associated uropathy.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2022, Volume: 28, Issue:6

    Topics: Cystitis; Humans; Ketamine; Pain; Urinary Bladder; Urologic Diseases

2022
Systematic review and meta-analysis of ketamine-associated uropathy.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2022, Volume: 28, Issue:6

    Topics: Cystitis; Humans; Ketamine; Pain; Urinary Bladder; Urologic Diseases

2022
Systematic review and meta-analysis of ketamine-associated uropathy.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2022, Volume: 28, Issue:6

    Topics: Cystitis; Humans; Ketamine; Pain; Urinary Bladder; Urologic Diseases

2022
Management of complications of ketamine abuse: 10 years' experience in Hong Kong.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2018, Volume: 24, Issue:2

    Topics: Gastrointestinal Diseases; Humans; Ketamine; Substance-Related Disorders; Urologic Diseases

2018
Ketamine: an update on its abuse.
    Journal of pharmacy practice, 2014, Volume: 27, Issue:6

    Topics: Gastrointestinal Diseases; Humans; Ketamine; Mental Disorders; Substance-Related Disorders; Urologic

2014
Ketamine: A Cause of Urinary Tract Dysfunction.
    Clinics in laboratory medicine, 2016, Volume: 36, Issue:4

    Topics: Analgesics; Cystitis; Diagnosis, Differential; Female; Humans; Ketamine; Lower Urinary Tract Symptom

2016
Recreational ketamine: from pleasure to pain.
    BJU international, 2011, Volume: 107, Issue:12

    Topics: Adolescent; Adult; Analgesics; Epidemiologic Methods; Humans; Illicit Drugs; Ketamine; Middle Aged;

2011
Lower urinary tract destruction due to ketamine: a report of 4 cases and review of literature.
    Journal of addiction medicine, 2012, Volume: 6, Issue:1

    Topics: Adult; Anesthetics, Dissociative; China; Female; Follow-Up Studies; Humans; Ketamine; Male; Substanc

2012
Ketamine for chronic noncancer pain: concerns regarding toxicity.
    Current opinion in supportive and palliative care, 2012, Volume: 6, Issue:2

    Topics: Analgesics; Chemical and Drug Induced Liver Injury; Chronic Pain; Cognition Disorders; Dose-Response

2012
Pediatric surgery. Current concepts.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:2

    Topics: Abdomen; Ambulatory Care; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Burns; Child; Ch

1974

Trials

3 trials available for ketamine and Urinary Tract Diseases

ArticleYear
Comparison of low-dose ketamine to midazolam for sedation during pediatric urodynamic study.
    Paediatric anaesthesia, 2013, Volume: 23, Issue:5

    Topics: Anesthetics, Dissociative; Blood Pressure; Child; Child, Preschool; Conscious Sedation; Double-Blind

2013
Ketamine anesthesia for short transurethral urologic procedures.
    Middle East journal of anaesthesiology, 1993, Volume: 12, Issue:2

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Double-Blind Method; Female; Hemodynamic

1993
[Ketamine at low doses + etomidate or diazepam--a comparative clinical study of anesthesia in urology].
    Khirurgiia, 1995, Volume: 48, Issue:5

    Topics: Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Diazepam; Drug Therapy, Combination; Etom

1995

Other Studies

25 other studies available for ketamine and Urinary Tract Diseases

ArticleYear
Ketamine uropathy: Clinical experience in a high prevalence center.
    Neurourology and urodynamics, 2023, Volume: 42, Issue:7

    Topics: Adult; Female; Humans; Hydronephrosis; Ketamine; Male; Prevalence; Substance-Related Disorders; Urol

2023
Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male.
    BMC urology, 2019, Oct-30, Volume: 19, Issue:1

    Topics: Adult; Dysuria; Humans; Ketamine; Male; Prostatic Hyperplasia; Substance-Related Disorders; Urologic

2019
Risk of Renal Function Decline in Patients with Ketamine-Associated Uropathy.
    International journal of environmental research and public health, 2020, 10-04, Volume: 17, Issue:19

    Topics: Adult; Analgesics; Cystitis; Female; Glomerular Filtration Rate; Humans; Hydronephrosis; Ketamine; K

2020
Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.
    Journal of digestive diseases, 2017, Volume: 18, Issue:9

    Topics: Abdominal Pain; Administration, Inhalation; Adolescent; Adult; Analgesics; Anemia; Case-Control Stud

2017
Histopathological characteristics of ketamine-associated uropathy and their clinical association.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:5

    Topics: Adult; Female; Humans; Ketamine; Male; Pelvic Pain; Ureter; Urodynamics; Urologic Diseases; Urologic

2018
Ketamine is associated with lower urinary tract signs and symptoms.
    Drug and alcohol dependence, 2013, Sep-01, Volume: 132, Issue:1-2

    Topics: Adult; Anesthetics, Dissociative; Data Collection; Data Interpretation, Statistical; Dysuria; Female

2013
One-stop clinic for ketamine-associated uropathy: report on service delivery model, patients' characteristics and non-invasive investigations at baseline by a cross-sectional study in a prospective cohort of 318 teenagers and young adults.
    BJU international, 2014, Volume: 114, Issue:5

    Topics: Adolescent; Adult; Analysis of Variance; Cross-Sectional Studies; Female; Hong Kong; Humans; Illicit

2014
Lessons learned from Asian Urology.
    BJU international, 2014, Volume: 114, Issue:5

    Topics: China; Hong Kong; Humans; Ketamine; Substance-Related Disorders; United Kingdom; Urologic Diseases;

2014
Where next in ketamine uropathy? Dedicated management centres?
    BJU international, 2014, Volume: 114, Issue:5

    Topics: Female; Humans; Illicit Drugs; Ketamine; Male; Pelvic Pain; Substance-Related Disorders; Urologic Di

2014
[A preliminary study on mechanisms for urinary system disorders before and after ketamine withdrawal in rats].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2015, Volume: 40, Issue:3

    Topics: Animals; Epithelium; Ketamine; Kidney; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Urinary Bla

2015
Re: One-stop clinic for ketamine-associated uropathy: report on service delivery model, patients' characteristics and non-invasive investigations at baseline by a cross-sectional study in a prospective cohort of 318 teenagers and young adults.
    The Journal of urology, 2015, Volume: 193, Issue:6

    Topics: Female; Humans; Illicit Drugs; Ketamine; Male; Pelvic Pain; Substance-Related Disorders; Urologic Di

2015
Clinical staging of ketamine-associated urinary dysfunction: a strategy for assessment and treatment.
    World journal of urology, 2016, Volume: 34, Issue:9

    Topics: Disease Progression; Female; Humans; Ketamine; Male; Retrospective Studies; Severity of Illness Inde

2016
The destruction of the lower urinary tract by ketamine abuse: a new syndrome?
    BJU international, 2008, Volume: 102, Issue:11

    Topics: Adolescent; Adult; Cystoscopy; Female; Humans; Ketamine; Male; Retrospective Studies; Substance-Rela

2008
Can ketamine prescribed for pain cause damage to the urinary tract?
    Palliative medicine, 2009, Volume: 23, Issue:7

    Topics: Adult; Aged; Analgesics; Fatal Outcome; Female; Humans; Ketamine; Male; Middle Aged; Pain; Palliativ

2009
Ketamine-associated lower urinary tract destruction: a new radiological challenge.
    Clinical radiology, 2010, Volume: 65, Issue:10

    Topics: Adolescent; Adult; Anesthetics, Dissociative; Cystoscopy; Delayed Diagnosis; Female; Humans; Ketamin

2010
Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.
    Singapore medical journal, 2011, Volume: 52, Issue:3

    Topics: Adult; Anesthetics, Dissociative; Biliary Tract; Cholangiopancreatography, Endoscopic Retrograde; Ch

2011
Ketamine-induced cholangiopathy: a case report.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:5

    Topics: Adult; Biliary Tract Diseases; Cholangiopancreatography, Endoscopic Retrograde; Diagnosis, Different

2011
Ketamine uropathy: rising to the challenges of a new condition.
    BJU international, 2012, Volume: 109, Issue:9

    Topics: Analgesics; Humans; Ketamine; Practice Guidelines as Topic; Urologic Diseases

2012
[Ketamine-associated urological symptoms].
    Nederlands tijdschrift voor geneeskunde, 2012, Volume: 156, Issue:10

    Topics: Cystoscopy; Female; Humans; Ketamine; Substance-Related Disorders; Urinary Tract; Urologic Diseases;

2012
Gourd-shaped bladder associated with ketamine abuse.
    Urologia internationalis, 2012, Volume: 89, Issue:1

    Topics: Adult; Cystitis; Dysuria; Hematuria; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms;

2012
[Anesthesia in pediatric urology].
    Zeitschrift fur Urologie und Nephrologie, 1980, Volume: 73, Issue:7

    Topics: Adolescent; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Inhalation; Anesthesia, Intravenous; C

1980
[Dissociative anesthesia with ketamine. Clinical contribution].
    Minerva medica, 1977, Jan-21, Volume: 68, Issue:3

    Topics: Eye Diseases; Female; Genital Diseases, Female; Humans; Ketamine; Male; Methods; Otorhinolaryngologi

1977
[Ketamine analgesia with low (subanesthetic) doses during endoscopic urological operations].
    Khirurgiia, 1990, Volume: 43, Issue:3

    Topics: Aged; Analgesia; Diazepam; Endoscopy; Evaluation Studies as Topic; Humans; Intraoperative Period; Ke

1990
[Use of Ketalar in urology].
    Hinyokika kiyo. Acta urologica Japonica, 1971, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthetics; Child; Child, Preschool; Cyclohexanes; Female; Humans; Injecti

1971
[The use of ketamine hydrochloride (Ketalar) for urological surgery and examinations].
    Hinyokika kiyo. Acta urologica Japonica, 1970, Volume: 16, Issue:10

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics; Child; Child, Preschool; Cyclohexanes; Fe

1970