Page last updated: 2024-10-29

ketamine and Urinary Retention

ketamine has been researched along with Urinary Retention in 3 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Urinary Retention: Inability to empty the URINARY BLADDER with voiding (URINATION).

Research Excerpts

Excerpt	Relevance	Reference
"Postoperative pain was assessed by means of a modified Objective Pain Score and analgesia was administered if this score exceeded four."	2.69	The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children. ( Aldridge, LM; Doyle, E; Findlow, D; Johnston, P, 1999)
"IVPCA ketamine in combination with morphine provides superior postsurgical pain relief at lower dosage and with fewer side effects than morphine alone."	2.68	Comparison of morphine and morphine with ketamine for postoperative analgesia. ( Colclough, GW; Javery, KB; Steger, HG; Ussery, TW, 1996)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bhattacharya, A	1
Gurnani, A	1
Sharma, PK	1
Sethi, AK	1
Javery, KB	1
Ussery, TW	1
Steger, HG	1
Colclough, GW	1
Johnston, P	1
Findlow, D	1
Aldridge, LM	1
Doyle, E	1

Clinical Trials (5)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients.[NCT00163969]	Phase 4	40 participants	Interventional	2002-04-30	Completed
PCA Ketamine-Morphine Versus PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.[NCT06010056]	Phase 4	60 participants (Actual)	Interventional	2018-04-05	Completed
PCA Ketamine-Morphine Versus PCA Morphine as Post-Operative Analgesia in Colorectal Surgery[NCT06021717]	Phase 4	60 participants (Actual)	Interventional	2018-04-05	Completed
Comparison of Intravenous Push Dose of Low Dose Ketamine to Short Infusion of Low Dose Ketamine for Treatment of Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study[NCT02363270]		48 participants (Actual)	Interventional	2015-04-01	Completed
Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department: A Prospective, Randomized, Double-Blind Study[NCT01835262]	Phase 4	90 participants (Actual)	Interventional	2013-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Rate of Feeling Unreality

Overall rate of feeling of unreality as measured by Side Effects Rating Scale for Dissociative Anesthetics (SERSDA) (NCT02363270)
Timeframe: 30 minutes

Intervention	Participants (Count of Participants)
IV Push Group	22
IV Drip Group	13

Numeric Rating Scale of Pain

"We will compare efficacy as a difference between 2 groups in pain score at 30 minutes post-analgesic administration. The primary outcome is the difference between 2 groups in pain score at 30 minutes.~Pain will be measured via Numeric rating scale from 0 to 10 with 0 being no pain, 5 being moderate pain, and 10 being severe pain" (NCT01835262)
Timeframe: 30 minutes

Intervention	Units on a scale (Mean)
Morphine	3.93
Ketamine Group	4.07

Trials

3 trials available for ketamine and Urinary Retention

Article	Year
Subcutaneous infusion of ketamine and morphine for relief of postoperative pain: a double-blind comparative study. Annals of the Academy of Medicine, Singapore, 1994, Volume: 23, Issue:4 Topics: Abdomen; Adult; Awareness; Double-Blind Method; Female; Humans; Infusion Pumps; Injections, Subcutan	1994
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
Comparison of morphine and morphine with ketamine for postoperative analgesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Diskectomy; Double-Blind Metho	1996
The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children. Paediatric anaesthesia, 1999, Volume: 9, Issue:1 Topics: Acetaminophen; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Anesthesia Recovery Period	1999