Page last updated: 2024-10-29

ketamine and Tachycardia

ketamine has been researched along with Tachycardia in 16 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
" A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported."7.68Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993)
"To compare the overall occurrence of hypertension and tachycardia immediately pre-intubation (post-induction) until 10 minutes post intubation between the study group receiving fentanyl at 1."5.30Effect of low-dose ketamine versus fentanyl on attenuating the haemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing general anaesthesia: a prospective, double-blinded, randomised controlled trial. ( Bal, R; Mung'ayi, V; Ongewe, A, 2019)
" A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported."3.68Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993)
"Intravenous ketamine dissociation anesthesia combined with epinephrine solution infiltration may provoke serious tachyarrhythmias despite diazepam premedication and the use of minimal doses of both drugs."3.67Cardiovascular reactions associated with the use of ketamine and epinephrine in plastic surgery. ( Behbahani, PM; Cabbabe, EB, 1985)
"Ketamine was associated with vomiting (14."2.68Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures. ( Barst, SM; McDowall, RH; Scher, CS, 1995)
"Tachycardia was the most common physical examination finding."1.31Ketamine abusers presenting to the emergency department: a case series. ( Bayer, MJ; McKay, CA; Vieira, L; Weiner, AL, 2000)
" The tmax was 2 to 4 hours after dosing, with nonlinear increases in Cmax and the AUC0-4th for HP 749."1.29The pharmacokinetics and cardiovascular pharmacodynamics of HP 749 (besipirdine HCl) and metabolite P86-7480 in the conscious monkey. ( Dean, R; Dileo, EM; Griffiths, L; Hintze, TH; Hsu, RS; Hubbard, JW; Natarajan, C, 1995)
"Hypertension was recorded in 11."1.28A retrospective survey of anaesthesia in horses with colic. ( Adams, JG; Cowgill, LM; Trim, CM; Ward, SL, 1989)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ongewe, A1
Mung'ayi, V1
Bal, R1
Tang, MHY1
Chong, YK1
Chan, CY1
Ching, CK1
Lai, CK1
Li, YK1
Mak, TWL1
Hofer, KE1
Grager, B1
Müller, DM1
Rauber-Lüthy, C1
Kupferschmidt, H1
Rentsch, KM1
Ceschi, A1
Kye, YC1
Rhee, JE1
Kim, K1
Kim, T1
Jo, YH1
Jeong, JH1
Lee, JH1
Shpilenia, LS1
McDowall, RH1
Scher, CS1
Barst, SM1
Hubbard, JW1
Hsu, RS1
Griffiths, L1
Natarajan, C1
Dean, R1
Dileo, EM1
Hintze, TH1
Munro, HM1
Sleigh, JW1
Paxton, LD1
Murphy, JL1
Trim, CM1
Adams, JG1
Cowgill, LM1
Ward, SL1
Weiner, AL1
Vieira, L1
McKay, CA1
Bayer, MJ1
Cabbabe, EB1
Behbahani, PM1
Shah, K1
Karlman, R1
Heller, J1
Wadhwa, RK1
Wadhwa, SR1
Khurana, RC1
Kaplan, JA1
Cooperman, LH1
Ginsberg, H1
Gerber, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Atropine Needed With Ketamine Sedation?[NCT00834470]Phase 4140 participants (Actual)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for ketamine and Tachycardia

ArticleYear
Effect of low-dose ketamine versus fentanyl on attenuating the haemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing general anaesthesia: a prospective, double-blinded, randomised controlled trial.
    African health sciences, 2019, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthetics; Double-Blind Method; Elective Surgical Procedures

2019
Clinical effects of adjunctive atropine during ketamine sedation in pediatric emergency patients.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Atropine; Child, Preschool; Conscious Sedation; Do

2012
Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures.
    Journal of clinical anesthesia, 1995, Volume: 7, Issue:4

    Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Child; Child, Preschool; Etomid

1995
The cardiovascular response to ketamine: the effects of clonidine and lignocaine.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:1

    Topics: Adult; Aged; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Ketamine; Lidocaine; Male

1993

Other Studies

12 other studies available for ketamine and Tachycardia

ArticleYear
Cluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE.
    Forensic science international, 2018, Volume: 290

    Topics: Adult; Chromatography, Liquid; Confusion; Consciousness Disorders; Female; Forensic Toxicology; Gas

2018
Ketamine-like effects after recreational use of methoxetamine.
    Annals of emergency medicine, 2012, Volume: 60, Issue:1

    Topics: Anesthetics, Dissociative; Confusion; Cyclohexanones; Cyclohexylamines; Dyskinesias; Humans; Hyperte

2012
[Experience with the use of ketamine in psychiatric practice].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984, Volume: 84, Issue:3

    Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Ketamine; Male; Nausea; Schi

1984
The pharmacokinetics and cardiovascular pharmacodynamics of HP 749 (besipirdine HCl) and metabolite P86-7480 in the conscious monkey.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:7

    Topics: Administration, Oral; Alzheimer Disease; Animals; Blood Pressure; Conscious Sedation; Dose-Response

1995
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ket

1993
A retrospective survey of anaesthesia in horses with colic.
    Equine veterinary journal. Supplement, 1989, Issue:7

    Topics: Administration, Inhalation; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthet

1989
Ketamine abusers presenting to the emergency department: a case series.
    The Journal of emergency medicine, 2000, Volume: 18, Issue:4

    Topics: Akathisia, Drug-Induced; Anesthetics, Dissociative; Anxiety; Chest Pain; Connecticut; Diagnosis, Dif

2000
Cardiovascular reactions associated with the use of ketamine and epinephrine in plastic surgery.
    Annals of plastic surgery, 1985, Volume: 15, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Cardiac Complexes, Premature; Diazepam; Dose-Respons

1985
Ventricular tachycardia and hypotension with amniotic fluid embolism during cesarean section.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Blood Pressure; Bupivacaine; Cesarean Section; Diazepam; Electrocard

1986
Cardiovascular collapse unrelated to anaesthesia. An undiagnosed ectopic pregnancy.
    Anaesthesia, 1974, Volume: 29, Issue:2

    Topics: Adult; Anesthesia, General; Blood Transfusion; Curettage; Dilatation; Female; Humans; Hypotension; K

1974
Alarming reactions to ketamine in patients taking thyroid medication--treatment with propranolol.
    Anesthesiology, 1971, Volume: 35, Issue:2

    Topics: Adult; Analgesics; Anesthesia, Intravenous; Cyclohexanes; Drug Synergism; Female; Humans; Hypertensi

1971
Ketamine hydrochloride: a clinical investigation in 60 children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, May-24, Volume: 43, Issue:21

    Topics: Analgesics; Anesthetics; Child; Child, Preschool; Chlorides; Cyclohexanes; Humans; Hypertension; Inf

1969