ketamine has been researched along with Spinal Diseases in 10 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Spinal Diseases: Diseases involving the SPINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results suggest that, using a transcranial multipulse stimulation, monitoring of motor-evoked potentials from the external anal sphincter is feasible during ketamine- and propofol-based anesthesia." | 5.10 | Intraoperative monitoring of myogenic motor-evoked potentials from the external anal sphincter muscle to transcranial electrical stimulation. ( Furuya, H; Inoue, S; Kakimoto, M; Kawaguchi, M; Kitaguchi, K; Morimoto, T; Sakaki, T; Sakamoto, T; Takashi, S, 2002) |
| "Propofol was replaced with ketamine if no reliable MEPs could be recorded." | 2.73 | Intraoperative monitoring of motor-evoked potentials in children undergoing spinal surgery. ( Duitmann, E; Erb, TO; Frei, FJ; Hasler, CC; Luetschg, J; Ryhult, SE, 2007) |
| "Ketamine has been reported to have little effect on MEPs but may produce adverse effects such as psychedelic effect and hypertension." | 1.31 | Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials. ( Furuya, H; Inoue, S; Kakimoto, M; Kawaguchi, M; Morimoto, T; Sakaki, T; Sakamoto, T, 2000) |
| "We report two cases of refractory pain in a spinal disease." | 1.30 | [Ketamine infusion therapy for refractory neuralgia in spinal disease: report of two cases]. ( Enomoto, T; Matsuda, W; Matsumura, A; Miyabe, M; Nose, T; Suga, A; Toyooka, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maheshwari, K | 1 |
| Avitsian, R | 1 |
| Sessler, DI | 1 |
| Makarova, N | 1 |
| Tanios, M | 1 |
| Raza, S | 1 |
| Traul, D | 1 |
| Rajan, S | 1 |
| Manlapaz, M | 1 |
| Machado, S | 1 |
| Krishnaney, A | 1 |
| Machado, A | 1 |
| Rosenquist, R | 1 |
| Kurz, A | 1 |
| Boenigk, K | 1 |
| Echevarria, GC | 1 |
| Nisimov, E | 1 |
| von Bergen Granell, AE | 1 |
| Cuff, GE | 1 |
| Wang, J | 1 |
| Atchabahian, A | 1 |
| Inoue, S | 2 |
| Kawaguchi, M | 2 |
| Takashi, S | 1 |
| Kakimoto, M | 2 |
| Sakamoto, T | 2 |
| Kitaguchi, K | 1 |
| Furuya, H | 2 |
| Morimoto, T | 2 |
| Sakaki, T | 2 |
| Frei, FJ | 1 |
| Ryhult, SE | 1 |
| Duitmann, E | 1 |
| Hasler, CC | 1 |
| Luetschg, J | 1 |
| Erb, TO | 1 |
| Yang, LH | 1 |
| Lin, SM | 1 |
| Lee, WY | 1 |
| Liu, CC | 1 |
| Raidal, SR | 1 |
| Raidal, SL | 1 |
| Richards, RB | 1 |
| Cosgriff, AV | 1 |
| Rose, KJ | 1 |
| Matsuda, W | 1 |
| Matsumura, A | 1 |
| Enomoto, T | 1 |
| Nose, T | 1 |
| Suga, A | 1 |
| Miyabe, M | 1 |
| Toyooka, H | 1 |
| Neufeld, JH | 1 |
| Machado, T | 1 |
| Margolin, L | 1 |
| Shin, FT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioid-Free Intravenous Anesthesia for Patients With Joint Hypermobility Syndrome Undergoing Craneo-Cervical Fixation: A Case-series Study Focused on Anti-hyperalgesic Approach[NCT04437589] | 42 participants (Actual) | Observational | 2018-09-06 | Completed | |||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| A Prospective, Randomized, Double Blinded Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion[NCT03274453] | Phase 2 | 129 participants (Actual) | Interventional | 2012-11-01 | Completed | ||
| The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283] | Phase 4 | 1,544 participants (Anticipated) | Interventional | 2021-04-12 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hydromorphone use during the first postoperative 24 hours in mg/kg (NCT03274453)
Timeframe: 24 Hours
| Intervention | mg/kg (Mean) |
|---|---|
| Naive Placebo | .13 |
| Naive Ketamine | .09 |
| Tolerant Placebo | .27 |
| Tolerant Ketamine | .19 |
4 trials available for ketamine and Spinal Diseases
| Article | Year |
|---|---|
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; D | 2019 |
Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; D | 2019 |
Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; D | 2019 |
Low-dose ketamine infusion reduces postoperative hydromorphone requirements in opioid-tolerant patients following spinal fusion: A randomised controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; D | 2019 |
Intraoperative monitoring of myogenic motor-evoked potentials from the external anal sphincter muscle to transcranial electrical stimulation.
Topics: Adolescent; Adult; Anal Canal; Anesthesia; Brain; Electric Stimulation; Evoked Potentials, Motor; Fe | 2002 |
Intraoperative monitoring of motor-evoked potentials in children undergoing spinal surgery.
Topics: Adolescent; Anesthetics, Intravenous; Child; Child, Preschool; Electric Stimulation; Evoked Potentia | 2007 |
6 other studies available for ketamine and Spinal Diseases
| Article | Year |
|---|---|
Intraoperative transcranial electrical motor evoked potential monitoring during spinal surgery under intravenous ketamine or etomidate anaesthesia.
Topics: Adult; Afferent Pathways; Aged; Anesthesia, Intravenous; Dominance, Cerebral; Electric Stimulation; | 1994 |
Acute paraplegia in a thoroughbred racehorse after general anaesthesia.
Topics: Acute Disease; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, General; Animals; Hemorr | 1997 |
[Ketamine infusion therapy for refractory neuralgia in spinal disease: report of two cases].
Topics: Analgesics; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Mal | 1999 |
Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Bra | 2000 |
Variables affecting disc size in the lumbar spine of rabbits: anesthesia, paralysis, and disc injury.
Topics: Acepromazine; Anesthesia, Spinal; Animals; Halothane; Intervertebral Disc; Ketamine; Lumbar Vertebra | 1991 |
Some anaesthetic problems in corrective spinal surgery in children in Hong Kong.
Topics: Anesthesia; Anesthesia, General; Blood Transfusion; Child; Hemorrhage; Hong Kong; Humans; Intubation | 1973 |