Page last updated: 2024-10-29

ketamine and Sore Throat

ketamine has been researched along with Sore Throat in 9 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"05% betamethasone gel over the Endotracheal tubes in decreasing postoperative sore throat."9.16Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice. ( Kamal, SM; Shaaban, AR, 2012)
"We searched MEDLINE, EMBASE, and CENTRAL through September 23, 2019 for randomized controlled trials in which at least one intervention was topical ketamine to prevent postoperative sore throat in adults undergoing endotracheal intubation."9.05Topical application of ketamine to prevent postoperative sore throat in adults: A systematic review and meta-analysis. ( Hino, M; Kamei, J; Kuriyama, A; Nakanishi, M; Ninomiya, K; Sun, R, 2020)
"The objective of this review was to determine the effectiveness of ketamine gargle in comparison to placebo or another intervention in reducing the incidence of postoperative sore throat in patients undergoing airway instrumentation."8.91Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review. ( Cress, K; Mayhood, J, 2015)
"05% betamethasone gel over the Endotracheal tubes in decreasing postoperative sore throat."5.16Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice. ( Kamal, SM; Shaaban, AR, 2012)
"We searched MEDLINE, EMBASE, and CENTRAL through September 23, 2019 for randomized controlled trials in which at least one intervention was topical ketamine to prevent postoperative sore throat in adults undergoing endotracheal intubation."5.05Topical application of ketamine to prevent postoperative sore throat in adults: A systematic review and meta-analysis. ( Hino, M; Kamei, J; Kuriyama, A; Nakanishi, M; Ninomiya, K; Sun, R, 2020)
"The objective of this review was to determine the effectiveness of ketamine gargle in comparison to placebo or another intervention in reducing the incidence of postoperative sore throat in patients undergoing airway instrumentation."4.91Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review. ( Cress, K; Mayhood, J, 2015)
"Postoperative sore throat is one of the most common complications following endotracheal intubation."2.66Nebulized pharmacological agents for preventing postoperative sore throat: A systematic review and network meta-analysis. ( Lv, F; Min, S; Ren, L; Yang, Y; Yu, J, 2020)
" However, before these agents are recommended for general use, large multicenter trials should be done exploring not only efficacy but also dose-response relationships and side effects."2.50Novel preoperative pharmacologic methods of preventing postoperative sore throat due to tracheal intubation. ( Austin, PN; Kalil, DM; Silvestro, LS, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Kuriyama, A1
Nakanishi, M1
Kamei, J1
Sun, R1
Ninomiya, K1
Hino, M1
Yu, J1
Ren, L1
Min, S1
Yang, Y1
Lv, F1
Aigbedia, SO1
Tobi, KU1
Amadasun, FE1
Tekelioglu, UY1
Apuhan, T1
Akkaya, A1
Demirhan, A1
Yildiz, I1
Simsek, T1
Gok, U1
Kocoglu, H1
Kalil, DM1
Silvestro, LS1
Austin, PN1
Mayhood, J1
Cress, K1
Chan, L1
Lee, ML1
Lo, YL1
Shaaban, AR1
Kamal, SM1
Canbay, O1
Celebi, N1
Sahin, A1
Celiker, V1
Ozgen, S1
Aypar, U1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Preoperative Chewing Gum on Anxiety and Sore Throat in Patients With Laryngeal Mask Airway: A Randomised Controlled Trial[NCT06168981]92 participants (Anticipated)Interventional2023-12-01Enrolling by invitation
Effect of Tramadol on Postoperative Sore Throat in Thyroid Surgery Under General Anesthesia With Endotracheal Intubation: A Randomized Controlled Trial[NCT04991493]Phase 4168 participants (Anticipated)Interventional2021-09-10Recruiting
Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant; Impact on Postoperative Sore Throat and Haemodynamics[NCT03031808]Phase 4100 participants (Anticipated)Interventional2017-10-31Recruiting
''Comparison of Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Reduction in Severity and Duration of Post-Operative Sore Throat. A Randomized Controlled Parallel Study.''[NCT05343429]Phase 460 participants (Anticipated)Interventional2022-04-01Recruiting
Incidence of Postoperative Sore Throat and Risks Analysis in Patients Undergoing General Anesthesia With Endotracheal Intubation: A Prospective Cross-sectional Study[NCT05354154]249 participants (Anticipated)Observational2022-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for ketamine and Sore Throat

ArticleYear
Topical application of ketamine to prevent postoperative sore throat in adults: A systematic review and meta-analysis.
    Acta anaesthesiologica Scandinavica, 2020, Volume: 64, Issue:5

    Topics: Administration, Topical; Analgesics; Humans; Ketamine; Pharyngitis; Postoperative Complications

2020
Nebulized pharmacological agents for preventing postoperative sore throat: A systematic review and network meta-analysis.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anesthesia, General; Bayes Theorem; Drug

2020
Novel preoperative pharmacologic methods of preventing postoperative sore throat due to tracheal intubation.
    AANA journal, 2014, Volume: 82, Issue:3

    Topics: Anesthesia, General; Anesthetics, Local; Anti-Inflammatory Agents; Aspirin; Azulenes; Benzydamine; C

2014
Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Analgesics; Anesthesia, General; Female; Humans; Incidence; Intubation, Intratrac

2015
Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Analgesics; Anesthesia, General; Female; Humans; Incidence; Intubation, Intratrac

2015
Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Analgesics; Anesthesia, General; Female; Humans; Incidence; Intubation, Intratrac

2015
Effectiveness of ketamine gargle in reducing postoperative sore throat in patients undergoing airway instrumentation: a systematic review.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Analgesics; Anesthesia, General; Female; Humans; Incidence; Intubation, Intratrac

2015

Trials

5 trials available for ketamine and Sore Throat

ArticleYear
A comparative study of ketamine gargle and lidocaine jelly application for the prevention of postoperative throat pain following general anaesthesia with endotracheal intubation.
    Nigerian journal of clinical practice, 2017, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Anesthesia, General; Double-Blind Method; Elective Surgical Procedures; Female; G

2017
Comparison of topical tramadol and ketamine in pain treatment after tonsillectomy.
    Paediatric anaesthesia, 2013, Volume: 23, Issue:6

    Topics: Administration, Topical; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Data Interpretatio

2013
Postoperative sore throat and ketamine gargle.
    British journal of anaesthesia, 2010, Volume: 105, Issue:1

    Topics: Adult; Analgesics; Double-Blind Method; Female; Humans; Intubation, Intratracheal; Ketamine; Pharyng

2010
Comparison between betamethasone gel applied over endotracheal tube and ketamine gargle for attenuating postoperative sore throat, cough and hoarseness of voice.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:4

    Topics: Adult; Anesthesia, General; Betamethasone; Cough; Elective Surgical Procedures; Female; Gels; Glucoc

2012
Ketamine gargle for attenuating postoperative sore throat.
    British journal of anaesthesia, 2008, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Anesthesia, General; Excitatory Amino Acid Antagonists; Female; Humans; Intubatio

2008