ketamine has been researched along with Sleep Wake Disorders in 8 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the prevalence of ketamine side effects in children receiving botulinum toxin injections for strabismus under ketamine anesthesia and to establish the prevalence, severity, and duration of ptosis in these children." | 7.76 | Ketamine and botulinum: a safe combinationfor the management of childhood strabismus. ( Al-Khalid, M; Noonan, CP; Owen, M; Rowe, FJ, 2010) |
| "This study included 127 patients with major depressive disorder or bipolar disorder who received ketamine treatments during a 12-day period." | 5.41 | Sleep improvement is associated with the antidepressant efficacy of repeated-dose ketamine and serum BDNF levels: a post-hoc analysis. ( Lan, X; Liu, W; Ning, Y; Wang, C; Wang, M; Zhan, Y; Zhang, B; Zheng, W; Zhou, Y, 2021) |
| "To determine the prevalence of ketamine side effects in children receiving botulinum toxin injections for strabismus under ketamine anesthesia and to establish the prevalence, severity, and duration of ptosis in these children." | 3.76 | Ketamine and botulinum: a safe combinationfor the management of childhood strabismus. ( Al-Khalid, M; Noonan, CP; Owen, M; Rowe, FJ, 2010) |
| "Ketamine is an N-methyl-D: -aspartate (NMDA) receptor antagonist with psychotogenic effects and for which there are diverse reports of whether pleasant or unpleasant dreams result during anaesthesia, post-operatively or after sub-anaesthetic use." | 2.74 | The incidence of unpleasant dreams after sub-anaesthetic ketamine. ( Blagrove, M; Brandner, B; Bromley, L; Curran, HV; Morgan, CJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, M | 1 |
| Zhang, B | 1 |
| Zhou, Y | 1 |
| Wang, C | 1 |
| Zheng, W | 1 |
| Liu, W | 1 |
| Zhan, Y | 1 |
| Lan, X | 1 |
| Ning, Y | 1 |
| Morena, M | 1 |
| Berardi, A | 1 |
| Peloso, A | 1 |
| Valeri, D | 1 |
| Palmery, M | 1 |
| Trezza, V | 1 |
| Schelling, G | 1 |
| Campolongo, P | 1 |
| Blagrove, M | 1 |
| Morgan, CJ | 1 |
| Curran, HV | 1 |
| Bromley, L | 1 |
| Brandner, B | 1 |
| Owen, M | 1 |
| Noonan, CP | 1 |
| Al-Khalid, M | 1 |
| Rowe, FJ | 1 |
| Lydic, R | 1 |
| Baghdoyan, HA | 1 |
| Pavarin, RM | 1 |
| Valentin, N | 1 |
| Bech, B | 1 |
| Chia, YY | 1 |
| Liu, K | 1 |
| Liu, YC | 1 |
| Chang, HC | 1 |
| Wong, CS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Mini-dose Dexmedetomidine-Esketamine Infusion on Sleep Quality in Older Patients Undergoing Knee or Hip Replacement Surgery: A Multicenter Randomized Controlled Trial[NCT05950646] | Phase 4 | 154 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for ketamine and Sleep Wake Disorders
| Article | Year |
|---|---|
Sleep improvement is associated with the antidepressant efficacy of repeated-dose ketamine and serum BDNF levels: a post-hoc analysis.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Depressive Disord | 2021 |
The incidence of unpleasant dreams after sub-anaesthetic ketamine.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Dreams; Emotions; Excitatory Amino Acid Antag | 2009 |
Adding ketamine in a multimodal patient-controlled epidural regimen reduces postoperative pain and analgesic consumption.
Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; A | 1998 |
5 other studies available for ketamine and Sleep Wake Disorders
| Article | Year |
|---|---|
Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: Consequences for the development of post-traumatic stress disorder.
Topics: Animals; Avoidance Learning; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Dr | 2017 |
Ketamine and botulinum: a safe combinationfor the management of childhood strabismus.
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Dissociative; Blepharoptosis; Botulinum Toxins, Ty | 2010 |
Ketamine and MK-801 decrease acetylcholine release in the pontine reticular formation, slow breathing, and disrupt sleep.
Topics: Acetylcholine; Animals; Cats; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Electroence | 2002 |
Substance use and related problems: a study on the abuse of recreational and not recreational drugs in Northern Italy.
Topics: Accidents, Traffic; Adult; Alcoholism; Amphetamines; Anxiety; Crack Cocaine; Depression; Female; Hal | 2006 |
Ketamine anaesthesia for electrocochleography in children. Are psychic side effects really rare?
Topics: Anesthetics, Local; Audiometry, Evoked Response; Child, Preschool; Hearing Disorders; Humans; Ketami | 1996 |