ketamine has been researched along with Sleep Apnea, Obstructive in 5 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capnography enables the measurement of end-tidal CO2 and thereby the early detection of apnea, prompting immediate intervention to restore ventilation." | 5.19 | Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014) |
| "A 57-year-old male with a documented history of obstructive sleep apnea with loud snoring received deep intravenous sedation with midazolam, fentanyl, ketamine, and propofol infusion and a left interscalene brachial plexus nerve block for a left biceps tendon repair." | 3.73 | Uvular edema secondary to snoring under deep sedation. ( Gerhardt, MA; Miller, RJ, 2006) |
| "Patients with a history of obstructive sleep apnea (OSA) were excluded." | 2.82 | Influence of premedication with alprazolam on the occurence of obstructive apneas. A prospective randomized double-blind study. ( Bonhomme, V; Brichant, JF; Courtois, AC; Deflandre, E; Degey, S; Poirrier, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedrich-Rust, M | 1 |
| Welte, M | 1 |
| Welte, C | 1 |
| Albert, J | 1 |
| Meckbach, Y | 1 |
| Herrmann, E | 1 |
| Kannengiesser, M | 1 |
| Trojan, J | 1 |
| Filmann, N | 1 |
| Schroeter, H | 1 |
| Zeuzem, S | 1 |
| Bojunga, J | 1 |
| Kandil, A | 1 |
| Subramanyam, R | 1 |
| Hossain, MM | 1 |
| Ishman, S | 1 |
| Shott, S | 1 |
| Tewari, A | 1 |
| Mahmoud, M | 1 |
| Deflandre, E | 1 |
| Bonhomme, V | 1 |
| Courtois, AC | 1 |
| Degey, S | 1 |
| Poirrier, R | 1 |
| Brichant, JF | 1 |
| Miller, RJ | 1 |
| Gerhardt, MA | 1 |
| Luscri, N | 1 |
| Tobias, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial of Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea[NCT05303987] | Phase 2 | 90 participants (Anticipated) | Interventional | 2022-10-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ketamine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Capnographic monitoring of propofol-based sedation during colonoscopy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono | 2014 |
Influence of premedication with alprazolam on the occurence of obstructive apneas. A prospective randomized double-blind study.
Topics: Adult; Aged; Alprazolam; Analgesics; Anesthetics, Intravenous; Colonoscopy; Double-Blind Method; Dru | 2016 |
3 other studies available for ketamine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Comparison of the combination of dexmedetomidine and ketamine to propofol or propofol/sevoflurane for drug-induced sleep endoscopy in children.
Topics: Airway Obstruction; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Causality; Child; | 2016 |
Uvular edema secondary to snoring under deep sedation.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Arm; Brachial Plexus; Edema; Fentanyl; Humans; | 2006 |
Monitored anesthesia care with a combination of ketamine and dexmedetomidine during magnetic resonance imaging in three children with trisomy 21 and obstructive sleep apnea.
Topics: Airway Obstruction; Anesthesia; Anesthetics, Dissociative; Child, Preschool; Conscious Sedation; Dex | 2006 |