Page last updated: 2024-10-29

ketamine and Serotonin Syndrome

ketamine has been researched along with Serotonin Syndrome in 2 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with risperidone (0."5.32Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004)
"Pretreatment with risperidone (0."1.32Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smalla, KH1
Sahin, J1
Putzke, J1
Tischmeyer, W1
Gundelfinger, ED1
Kreutz, MR1
Nisijima, K1
Shioda, K1
Yoshino, T1
Takano, K1
Kato, S1

Other Studies

2 other studies available for ketamine and Serotonin Syndrome

ArticleYear
Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis.
    Neurochemical research, 2009, Volume: 34, Issue:8

    Topics: Animals; Blotting, Western; Calcium-Binding Proteins; Excitatory Amino Acid Antagonists; Ketamine; M

2009
Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Clorgyline; Disease Models, Animal; Dizocilpine Male

2004