ketamine has been researched along with Reperfusion Injury in 46 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary aim of this study was to compare the effects of a small-dose infusion of 2 antioxidant agents, ketamine and lidocaine, on ischemia-reperfusion injury (IRI) in patients undergoing elective lower limb surgery." | 9.30 | The effects of ketamine and lidocaine on free radical production after tourniquet-induced ischemia-reperfusion injury in adults. ( Deyişli, C; Kıyıcı, A; Ökesli, S; Peker, K, 2019) |
| "To determine the effects of a small-dose ketamine-propofol combination used for sedation during spinal anesthesia on tourniquet-induced ischemia-reperfusion injury." | 9.19 | The effects of a small-dose ketamine-propofol combination on tourniquet-induced ischemia-reperfusion injury during arthroscopic knee surgery. ( Akan, B; Baydar, M; Bayrakci, S; Girgin, G; Gogus, N, 2014) |
| "Male Sprague Dawley rats received a CO2 pneumoperitoneum of 15 mmHg and preceded by either low-dose ketamine (KP1, 5 mg/kg; KP2, 10 mg/kg) or 0." | 7.80 | Low-dose ketamine pretreatment reduces oxidative damage and inflammatory response following CO2 pneumoperitoneum in rats. ( Bowen, D; Jieshou, L; Ning, L; Peng, Z; Tao, F; Wu, J; Xiaoming, K; Xin, G; Xingwei, X, 2014) |
| "Low-dose ketamine preconditioning can reduce the inflammatory reaction and lessen oxidative damage in the intestinal mucosa following pneumoperitoneum in rats." | 7.79 | [Protective effect of low-dose ketamine against intestinal ischemia-reperfusion injury following carbon dioxide pneumoperitoneum in rats]. ( Tian, F; Wang, W; Yan, L, 2013) |
| "To investigate blood creatinine and renal histology in rats anesthetized with S(+)-ketamine (keta) or dexmedetomidine (dex) and submitted to kidney ischemia/reperfusion injury (IRI)." | 7.77 | Dexmedetomidine and S(+)-ketamine in ischemia and reperfusion injury in the rat kidney. ( Braz, JR; Castiglia, YM; Curtis, FG; Fiorio, PM; Oliveira, C; Silva, LM; Vianna, PT; Viero, RM, 2011) |
| "To investigate the effects of ketamine pretreatment on cerebral edema following brain ischemia reperfusion injury in rats and assess the involvement of Aquaporin 4 (AQP4) expression." | 7.76 | [The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats]. ( Cai, SN; Zhu, SM, 2010) |
| "To determine if the inhibitory effects of ketamine on the extracellular signal-regulated kinase (ERK) 1/2 are involved in reduction of the hyperglycemia-exaggerated cerebral ischemic lesion, rats with normoglycemia, hyperglycemia, or hyperglycemia supplemented with ketamine were subjected to 15 min of forebrain ischemia, and then, reperfusion for 0." | 7.74 | Inhibitory effect of ketamine on phosphorylation of the extracellular signal-regulated kinase 1/2 following brain ischemia and reperfusion in rats with hyperglycemia. ( Guo, FY; Jing, L; Ma, Y; Wang, YL; Zhang, JZ, 2007) |
| "Ketamine was able to diminish alterations induced by I/R." | 5.36 | Ketamine and the myenteric plexus in intestinal ischemia/reperfusion injury. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-de la Garza, FJ, 2010) |
| "Ketamine pretreatment was administered by intraperitoneal injections at doses of 100, 50, 12." | 5.36 | Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-De La Garza, FJ, 2010) |
| "After cerebral ischemia/reperfusion, the relative protein concentration of Bax was increased by 110% in control animals compared with the dexmedetomidine- and S(+)-ketamine-treated rats and by 140% compared with the sham-operated animals." | 5.32 | The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. ( Bachl, M; Blobner, M; Eberspächer, E; Engelhard, K; Hildt, E; Hutzler, P; Kochs, E; Werner, C, 2003) |
| "The primary aim of this study was to compare the effects of a small-dose infusion of 2 antioxidant agents, ketamine and lidocaine, on ischemia-reperfusion injury (IRI) in patients undergoing elective lower limb surgery." | 5.30 | The effects of ketamine and lidocaine on free radical production after tourniquet-induced ischemia-reperfusion injury in adults. ( Deyişli, C; Kıyıcı, A; Ökesli, S; Peker, K, 2019) |
| "To determine the effects of a small-dose ketamine-propofol combination used for sedation during spinal anesthesia on tourniquet-induced ischemia-reperfusion injury." | 5.19 | The effects of a small-dose ketamine-propofol combination on tourniquet-induced ischemia-reperfusion injury during arthroscopic knee surgery. ( Akan, B; Baydar, M; Bayrakci, S; Girgin, G; Gogus, N, 2014) |
| "Male Sprague Dawley rats received a CO2 pneumoperitoneum of 15 mmHg and preceded by either low-dose ketamine (KP1, 5 mg/kg; KP2, 10 mg/kg) or 0." | 3.80 | Low-dose ketamine pretreatment reduces oxidative damage and inflammatory response following CO2 pneumoperitoneum in rats. ( Bowen, D; Jieshou, L; Ning, L; Peng, Z; Tao, F; Wu, J; Xiaoming, K; Xin, G; Xingwei, X, 2014) |
| "Low-dose ketamine preconditioning can reduce the inflammatory reaction and lessen oxidative damage in the intestinal mucosa following pneumoperitoneum in rats." | 3.79 | [Protective effect of low-dose ketamine against intestinal ischemia-reperfusion injury following carbon dioxide pneumoperitoneum in rats]. ( Tian, F; Wang, W; Yan, L, 2013) |
| "To investigate blood creatinine and renal histology in rats anesthetized with S(+)-ketamine (keta) or dexmedetomidine (dex) and submitted to kidney ischemia/reperfusion injury (IRI)." | 3.77 | Dexmedetomidine and S(+)-ketamine in ischemia and reperfusion injury in the rat kidney. ( Braz, JR; Castiglia, YM; Curtis, FG; Fiorio, PM; Oliveira, C; Silva, LM; Vianna, PT; Viero, RM, 2011) |
| "5 mg/kg ketamine pretreatment showed significant protective effect on acute lung injury induced by HIR, which might be mediated by the NF-κB pathway." | 3.77 | A single small dose of ketamine prevents lung injury following hepatic ischemia-reperfusion in rabbits. ( Jin, L; Shen, H; Zhou, Y; Zhuang, X, 2011) |
| "To investigate the effects of ketamine pretreatment on cerebral edema following brain ischemia reperfusion injury in rats and assess the involvement of Aquaporin 4 (AQP4) expression." | 3.76 | [The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats]. ( Cai, SN; Zhu, SM, 2010) |
| "To determine if the inhibitory effects of ketamine on the extracellular signal-regulated kinase (ERK) 1/2 are involved in reduction of the hyperglycemia-exaggerated cerebral ischemic lesion, rats with normoglycemia, hyperglycemia, or hyperglycemia supplemented with ketamine were subjected to 15 min of forebrain ischemia, and then, reperfusion for 0." | 3.74 | Inhibitory effect of ketamine on phosphorylation of the extracellular signal-regulated kinase 1/2 following brain ischemia and reperfusion in rats with hyperglycemia. ( Guo, FY; Jing, L; Ma, Y; Wang, YL; Zhang, JZ, 2007) |
| "The aim of this study was to investigate any possible protective effect of ketamine in acute muscular ischaemia and reperfusion injury by measuring malondialdehyde using thiobarbituric acid assay in rats." | 3.73 | The effect of ketamine on acute muscular ischaemia reperfusion in rats. ( Aypar, U; Dal, D; Iskit, AB; Salman, AE; Salman, MA, 2005) |
| " Pretreatment with N-methyl-D-aspartate (NMDA) receptor antagonist ketamine, non-NMDA receptor antagonist DNQX, or NF-kappaB inhibitor PDTC decreased the IKK activity following brain ischemia 30 min." | 3.72 | Modulation of IkappaB kinase autophosphorylation and activity following brain ischemia. ( Shen, WH; Zhang, CY; Zhang, GY, 2003) |
| "The effects of three drugs including ketamine(KT), a noncompetitive antagonist of NMDA receptor (NR), nifedipine(ND), a voltage gated calcium channel (VGCC) antagonist and 6, 7dinitroquinoxaline -2, 3-dione(DNQX), a non-NMDA receptor antagonist on the contents of phospho-tyrosine proteins (p-tyr-pr) in the synaptosomal(P2), the crude membrane (P3), and the cytosolic (S3) fractions of hippocampus in forebrain ischemia of mongolian gerbils were studied." | 3.71 | [Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus]. ( Gui, ZH; Li, Y; Pei, L; Zhang, GY; Zhu, ZM, 2001) |
| " To evaluate the role played by NMDA antagonists in ischemia-reperfusion injury of the cochlea, 3 noncompetitive NMDA antagonists--ketamine, dextromethorphan, and MK-801--were administered to 53 albino guinea pigs subjected to transient ischemia of 30 minutes' duration, and the threshold shifts of the compound action potential were compared with those of nontreated animals 4 hours after the onset of recirculation." | 3.71 | Effect of ketamine, dextromethorphan, and MK-801 on cochlear dysfunction induced by transient ischemia. ( Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Tsuji, S; Wada, T, 2002) |
| "Ketamine has proposed anti-inflammatory effects and has been used for treating CRPS." | 1.42 | Preventive Treatment with Ketamine Attenuates the Ischaemia-Reperfusion Response in a Chronic Postischaemia Pain Model. ( Cheung, CW; Choi, SW; Irwin, M; Liman, S; Ng, KF; Qiu, Q; Tai, W; Wong, KL, 2015) |
| "Acute kidney injury is associated with the activation of NMDA receptors, as well as significant oxidative stress." | 1.39 | Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury. ( Arora, S; Kaur, T; Pundir, M; Singh, AP; Singh, R, 2013) |
| "Mannitol flux was greater in ischemic tissues than in reperfused tissues." | 1.37 | In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion. ( Freeman, DE; Graham, AS; Grosche, A; Morton, AJ; Polyak, MM, 2011) |
| "Ketamine was able to diminish alterations induced by I/R." | 1.36 | Ketamine and the myenteric plexus in intestinal ischemia/reperfusion injury. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-de la Garza, FJ, 2010) |
| "Ketamine pretreatment was administered by intraperitoneal injections at doses of 100, 50, 12." | 1.36 | Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-De La Garza, FJ, 2010) |
| "After cerebral ischemia/reperfusion, the relative protein concentration of Bax was increased by 110% in control animals compared with the dexmedetomidine- and S(+)-ketamine-treated rats and by 140% compared with the sham-operated animals." | 1.32 | The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. ( Bachl, M; Blobner, M; Eberspächer, E; Engelhard, K; Hildt, E; Hutzler, P; Kochs, E; Werner, C, 2003) |
| "Halothane alone was of no benefit." | 1.28 | Protecting the ischemic spinal cord during aortic clamping. The influence of anesthetics and hypothermia. ( Facundus, EC; Hollier, LH; Money, SR; Naslund, TC; Skenderis, BS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.70) | 18.2507 |
| 2000's | 18 (39.13) | 29.6817 |
| 2010's | 21 (45.65) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Verney, C | 1 |
| Legouis, D | 1 |
| Placier, S | 1 |
| Migeon, T | 1 |
| Bonnin, P | 1 |
| Buob, D | 1 |
| Hadchouel, J | 1 |
| Galichon, P | 1 |
| Zhu, L | 2 |
| Zhang, Y | 7 |
| Chen, G | 1 |
| Kamat, PK | 1 |
| Ahmad, AS | 1 |
| Doré, S | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 7 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 3 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Li, X | 5 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 5 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
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| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
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| Xu, JY | 1 |
| Genko, N | 1 |
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| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 3 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
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| You, Q | 1 |
| Cai, Q | 1 |
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| Gui, C | 1 |
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| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 8 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
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| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
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| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
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| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
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| Yu, X | 2 |
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| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
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| Schlom, DG | 1 |
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| Laukhtina, E | 1 |
| Glybochko, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411] | Phase 2 | 80 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ketamine and Reperfusion Injury
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
4 trials available for ketamine and Reperfusion Injury
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The effects of ketamine and lidocaine on free radical production after tourniquet-induced ischemia-reperfusion injury in adults.
Topics: Adult; Biomarkers; Free Radicals; Humans; Ketamine; Lactates; Lidocaine; Lower Extremity; Reperfusio | 2019 |
The effects of a small-dose ketamine-propofol combination on tourniquet-induced ischemia-reperfusion injury during arthroscopic knee surgery.
Topics: Adult; Analgesics; Anesthesia, Spinal; Anesthetics, Combined; Anesthetics, Intravenous; Arthroscopy; | 2014 |
Ketamine sedation during spinal anesthesia for arthroscopic knee surgery reduced the ischemia-reperfusion injury markers.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Dissociative; Anterior Cruciate Ligament; Arthroscopy; Bioma | 2005 |
41 other studies available for ketamine and Reperfusion Injury
| Article | Year |
|---|---|
Anaesthesia-Induced Transcriptomic Changes in the Context of Renal Ischemia Uncovered by the Use of a Novel Clamping Device.
Topics: Anesthesia; Animals; Disease Models, Animal; Ketamine; Kidney; Kidney Diseases; Male; Mice; Reperfus | 2021 |
Discovery of novel ketamine-inspired derivatives as a protective agent against renal ischemic/reperfusion injury in Wistar rats.
Topics: Animals; Apoptosis; Ischemia; Ketamine; Kidney; NF-kappa B; Protective Agents; Rats; Rats, Wistar; R | 2022 |
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti | 2020 |
Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects.
Topics: Acute Lung Injury; Animals; Blotting, Western; DNA Helicases; Immunohistochemistry; Ketamine; Liver; | 2017 |
Ketamine ameliorates ischemia-reperfusion injury after liver autotransplantation by suppressing activation of Kupffer cells in rats.
Topics: Animals; Apoptosis; Cytoprotection; Hepatocytes; Ketamine; Kupffer Cells; Liver Transplantation; Mal | 2018 |
Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury.
Topics: Acute Kidney Injury; Allosteric Site; Animals; Catalase; Glutamic Acid; Glutathione; Ketamine; Kynur | 2013 |
[Protective effect of low-dose ketamine against intestinal ischemia-reperfusion injury following carbon dioxide pneumoperitoneum in rats].
Topics: Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Interleukin- | 2013 |
Low-dose ketamine pretreatment reduces oxidative damage and inflammatory response following CO2 pneumoperitoneum in rats.
Topics: Animals; Carbon Dioxide; Interleukin-6; Ketamine; Male; Malondialdehyde; Oxidative Stress; Pneumoper | 2014 |
Preventive Treatment with Ketamine Attenuates the Ischaemia-Reperfusion Response in a Chronic Postischaemia Pain Model.
Topics: Analgesics; Animals; Behavior, Animal; Chronic Disease; Complex Regional Pain Syndromes; Disease Mod | 2015 |
Ischemic Postconditioning and Subanesthetic S(+)-Ketamine Infusion: Effects on Renal Function and Histology in Rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Infusions, Intravenous; Ischemic Postconditioning; Ketamin | 2015 |
Ketamine anesthesia reduces intestinal ischemia/reperfusion injury in rats.
Topics: Anesthetics, Dissociative; Animals; Disease Models, Animal; Gastrointestinal Motility; Intestinal Di | 2008 |
Effects of ketamine on the balance of ions Ca2+, Mg2+, Cu2+ and Zn2+ in the ischemia-reperfusion affected spinal cord tissues in rabbits.
Topics: Animals; Aorta, Abdominal; Calcium; Cations, Divalent; Constriction; Copper; Disease Models, Animal; | 2009 |
The comparison of the effects of anesthetic doses of ketamine, propofol, and etomidate on ischemia-reperfusion injury in skeletal muscle.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Disease Models, Animal; Etomidate; Fem | 2010 |
The effects of NMDA receptor antagonists over intestinal ischemia/reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Antithrombin III; Aspartate Aminotransferases; Biomarke | 2009 |
Ketamine and the myenteric plexus in intestinal ischemia/reperfusion injury.
Topics: Animals; Antithrombin III; Benzalkonium Compounds; Biomarkers; Disease Models, Animal; Immunohistoch | 2010 |
Ischemia-reperfusion injury in skeletal muscle: comparison of the effects of subanesthetic doses of ketamine, propofol, and etomidate.
Topics: Anesthetics; Animals; Catalase; Etomidate; Female; Glutathione Peroxidase; Ketamine; Malondialdehyde | 2010 |
Thiopental improves renal ischemia-reperfusion injury.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Antioxidants; Catalase; Etomidate; Fat | 2010 |
[The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats].
Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Ischemia; Ischemic Preconditioning; Ketamine; Male; | 2010 |
Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats.
Topics: Analysis of Variance; Animals; Antithrombin III; Disease Models, Animal; Excitatory Amino Acid Antag | 2010 |
[Effects of ischemia/reperfusion on the phosphotyrosine proteins contents in hippocampus].
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Excitatory Amino Acid Antagonis | 2001 |
Dexmedetomidine and S(+)-ketamine in ischemia and reperfusion injury in the rat kidney.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics; Animals; Creatinine; Dexmedetomidine; Ketamine; K | 2011 |
In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Colon; Diazepam; Electric Impedance; Horse | 2011 |
A single small dose of ketamine prevents lung injury following hepatic ischemia-reperfusion in rabbits.
Topics: Acute Lung Injury; Animals; Blood Pressure; Heart Rate; Immunohistochemistry; Intercellular Adhesion | 2011 |
Ischemia-reperfusion injury of the mouse kidney.
Topics: Anesthetics, General; Animals; Disease Models, Animal; Female; Hypnotics and Sedatives; Isoflurane; | 2012 |
N-methyl-D-aspartate receptor and L-type voltage-gated Ca(2+) channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Caspase 3; Caspase Inhi | 2002 |
The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Apoptosis; Blood Gas Analy | 2003 |
Modulation of IkappaB kinase autophosphorylation and activity following brain ischemia.
Topics: Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Hippocampus; I-kappa B Kinase; Ketamine; | 2003 |
[Effects of ketamine-midazolam anesthesia on focal cerebral ischemic injury in rats].
Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Apoptosis; Infarct | 2004 |
The effect of ketamine on acute muscular ischaemia reperfusion in rats.
Topics: Anesthetics, Dissociative; Animals; Female; Ischemia; Ketamine; Lipid Peroxidation; Lipid Peroxides; | 2005 |
Inhibitory effect of ketamine on phosphorylation of the extracellular signal-regulated kinase 1/2 following brain ischemia and reperfusion in rats with hyperglycemia.
Topics: Animals; Apoptosis; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid A | 2007 |
Heat shock proteins following rat cerebral ischemic/reperfusion episode: effect of ketamine.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Hippocampus; HSP70 Heat-Shock Prot | 1994 |
[Studies on the mechanism of protection of cultured neurous by ketamine anoxia/reoxygenation-induced injury].
Topics: Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fetus; Ketamine; L-Lac | 1997 |
NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Focal Adhesion Kinase 2; Hippocampus; Im | 2001 |
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion.
Topics: Animals; Calcium Channel Blockers; Genistein; Gerbillinae; Hippocampus; Ischemic Attack, Transient; | 2000 |
Changes and mechanisms of protein-tyrosine kinase and protein-tyrosine phosphatase activities after brain ischemia/reperfusion.
Topics: Animals; Calcium Channel Blockers; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ketamine; N | 2000 |
Effect of ketamine, dextromethorphan, and MK-801 on cochlear dysfunction induced by transient ischemia.
Topics: Action Potentials; Animals; Cochlea; Dextromethorphan; Dizocilpine Maleate; Guinea Pigs; Ketamine; R | 2002 |
Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cerebral Infarction; DNA Fragmentation; Excitatory Amino Acid Antagonists; | 2002 |
Nuclear factor kappaB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca(2+) channel following severe global ischemia in rat hippocampus.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Cytoplasm; Excitatory A | 2002 |
[Effect of ischemia/reperfusion on the phosphorylation of synaptosomal tyrosine of hippocampus of Mongolian gerbils].
Topics: Animals; Brain Ischemia; Calcium Channels, L-Type; Gerbillinae; Hippocampus; Ketamine; Nifedipine; P | 2000 |
Protecting the ischemic spinal cord during aortic clamping. The influence of anesthetics and hypothermia.
Topics: Anesthetics; Animals; Aorta, Abdominal; Constriction; Halothane; Hypothermia, Induced; Intraoperativ | 1992 |
Effects of taurine and ketamine on bovine retinal membrane lipid peroxidation.
Topics: Animals; Ascorbic Acid; Cadmium; Cadmium Chloride; Calcium; Cattle; Dextromethorphan; Female; Ischem | 1991 |