ketamine has been researched along with Psychomotor Agitation in 73 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexmedetomidine and ketamine appear to prevent postoperative agitation and pain after sevoflurane anesthesia for pediatric strabismus surgery." | 9.17 | Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. ( Chen, JY; Jia, JE; Li, WX; Liu, TJ; Qin, MJ, 2013) |
| "We investigated the effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in children undergoing elective strabismus surgery." | 9.10 | [The effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in pediatric strabismus surgery]. ( Fukumitsu, K; Hirao, O; Kawaraguchi, Y; Kinouchi, K; Kitamura, S; Miyamoto, Y; Taniguchi, A, 2002) |
| "Ketamine is widely used in emergency departments (EDs) to facilitate painful procedures; however, existing descriptors of predictors of emesis and recovery agitation are derived from relatively small studies." | 8.85 | Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children. ( Agrawal, D; Brown, L; Garcia Pena, BM; Gerber, AC; Green, SM; Hostetler, MA; Krauss, B; Losek, JD; McGlone, RG; McKee, M; Pitetti, RD; Roback, MG; Treston, G; Wathen, JE; Weiss, M, 2009) |
| "The present study attempted to elucidate whether intravesical instillation of platelet-rich plasma (PRP) could decrease bladder inflammation and ameliorate bladder hyperactivity in ketamine ulcerative cystitis (KIC) rat model." | 8.12 | Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model. ( Chuang, SM; Chueh, KS; Huang, KH; Juan, TJ; Juan, YS; Lee, YC; Lin, RJ; Long, CY; Lu, JH; Shen, MC; Sun, TW, 2022) |
| "To determine the effectiveness of intravenous (IV) ketamine on anxiety, irritability, agitation, and suicidality, in adults with treatment-resistant major depressive disorder (MDD) or bipolar disorder (BD)." | 7.96 | The effectiveness of ketamine on anxiety, irritability, and agitation: Implications for treating mixed features in adults with major depressive or bipolar disorder. ( Cha, DS; Fagiolini, A; Gill, H; Ho, R; Kratiuk, K; Lee, Y; Lin, K; Lipsitz, O; Malhi, GS; Mansur, RB; McIntyre, RS; Nasri, F; Rodrigues, NB; Rosenblat, JD; Subramaniapillai, M; Suppes, T; Vinberg, M, 2020) |
| "We report a case series on the observed effects of low-dose ketamine infusions in 4 critically ill patients with varying complications related to prolonged critical illness." | 7.83 | Low-Dose Ketamine in Chronic Critical Illness. ( Darrah, D; Moitra, A; Moitra, VK; Patel, MK; Wunsch, H, 2016) |
| "Ketamine has a role for agitation management in the prehospital setting; however, emergency personnel education and ketamine protocols should be utilized to aid in safe and effective pharmacotherapy and provide guidance on the management of adverse events." | 6.58 | Ketamine for the Acute Management of Excited Delirium and Agitation in the Prehospital Setting. ( Linder, LM; Ross, CA; Weant, KA, 2018) |
| "Ketamine is a noncompetitive N-methyl-D-aspartic acid receptor antagonist, making it an effective dissociative agent." | 5.46 | A Novel Agent for Management of Agitated Delirium: A Case Series of Ketamine Utilization in the Pediatric Emergency Department. ( Kopec, KT; Kowalski, JM; Lavelle, J; Osterhoudt, K, 2017) |
| "We conducted a randomized clinical trial comparing the rapidity of onset, level of sedation, and adverse effect profile of ketamine compared to a combination of midazolam and haloperidol for behavioral control of emergency department patients with severe psychomotor agitation." | 5.41 | Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial. ( Andolfatto, G; Barbic, D; Barbic, SP; Grunau, B; Honer, WG; Macewan, B; Qian, H; Scheuermeyer, FX; Wong, H, 2021) |
| "We present a novel study to determine whether ketamine is a rapid and safe option, compared to a combination of midazolam and haloperidol for the sedation of patients presenting to the ED with psychomotor agitation and violent behavior." | 5.27 | Rapid agitation control with ketamine in the emergency department (RACKED): a randomized controlled trial protocol. ( Andolfatto, G; Barbic, D; Barbic, SP; Grunau, B; Honer, WG; MacEwan, W; Scheuermeyer, FX; Wong, H, 2018) |
| "Dexmedetomidine and ketamine appear to prevent postoperative agitation and pain after sevoflurane anesthesia for pediatric strabismus surgery." | 5.17 | Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. ( Chen, JY; Jia, JE; Li, WX; Liu, TJ; Qin, MJ, 2013) |
| "We investigated the effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in children undergoing elective strabismus surgery." | 5.10 | [The effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in pediatric strabismus surgery]. ( Fukumitsu, K; Hirao, O; Kawaraguchi, Y; Kinouchi, K; Kitamura, S; Miyamoto, Y; Taniguchi, A, 2002) |
| "Ketamine is widely used in emergency departments (EDs) to facilitate painful procedures; however, existing descriptors of predictors of emesis and recovery agitation are derived from relatively small studies." | 4.85 | Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children. ( Agrawal, D; Brown, L; Garcia Pena, BM; Gerber, AC; Green, SM; Hostetler, MA; Krauss, B; Losek, JD; McGlone, RG; McKee, M; Pitetti, RD; Roback, MG; Treston, G; Wathen, JE; Weiss, M, 2009) |
| "The present study attempted to elucidate whether intravesical instillation of platelet-rich plasma (PRP) could decrease bladder inflammation and ameliorate bladder hyperactivity in ketamine ulcerative cystitis (KIC) rat model." | 4.12 | Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model. ( Chuang, SM; Chueh, KS; Huang, KH; Juan, TJ; Juan, YS; Lee, YC; Lin, RJ; Long, CY; Lu, JH; Shen, MC; Sun, TW, 2022) |
| "To determine the effectiveness of intravenous (IV) ketamine on anxiety, irritability, agitation, and suicidality, in adults with treatment-resistant major depressive disorder (MDD) or bipolar disorder (BD)." | 3.96 | The effectiveness of ketamine on anxiety, irritability, and agitation: Implications for treating mixed features in adults with major depressive or bipolar disorder. ( Cha, DS; Fagiolini, A; Gill, H; Ho, R; Kratiuk, K; Lee, Y; Lin, K; Lipsitz, O; Malhi, GS; Mansur, RB; McIntyre, RS; Nasri, F; Rodrigues, NB; Rosenblat, JD; Subramaniapillai, M; Suppes, T; Vinberg, M, 2020) |
| "We report a case series on the observed effects of low-dose ketamine infusions in 4 critically ill patients with varying complications related to prolonged critical illness." | 3.83 | Low-Dose Ketamine in Chronic Critical Illness. ( Darrah, D; Moitra, A; Moitra, VK; Patel, MK; Wunsch, H, 2016) |
| " The objective is to demonstrate that ketamine, given as a single intramuscular injection for violent and agitated patients, including those with suspected excited delirium syndrome (ExDS), is both safe and effective during the prehospital phase of care, and allows for the rapid sedation and control of this difficult patient population." | 3.80 | Prehospital use of i.m. ketamine for sedation of violent and agitated patients. ( Braghiroli, J; Chait, R; Scheppke, KA; Shalaby, M, 2014) |
| "This is the first confirmed case to be reported of toxicity with delayed onset of severe agitation, hallucinations and tonic-clonic seizures associated with recreational use of Bromo-dragonFLY (1-(8-bromobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane) in combination with ketamine and cannabis." | 3.75 | Delayed onset of seizures and toxicity associated with recreational use of Bromo-dragonFLY. ( Button, J; Dargan, PI; Davies, S; Holt, DW; Lidder, S; Looker, JJ; Puchnarewicz, M; Ramsey, J; Shaikh, L; Wood, DM, 2009) |
| "The incidence of postoperative pain was significantly less in the KETODEX group (15." | 2.80 | The effect of KETODEX on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane based-anesthesia. ( Daoud, A; Hadi, SM; Mei, X; Ouyang, W; Saleh, AJ; Tang, YZ, 2015) |
| "Tramadol was used for postoperative analgesia." | 2.71 | Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2004) |
| "Ketamine has a role for agitation management in the prehospital setting; however, emergency personnel education and ketamine protocols should be utilized to aid in safe and effective pharmacotherapy and provide guidance on the management of adverse events." | 2.58 | Ketamine for the Acute Management of Excited Delirium and Agitation in the Prehospital Setting. ( Linder, LM; Ross, CA; Weant, KA, 2018) |
| "When ketamine was administered in the ED, the intubation rate was 1." | 2.58 | Ketamine for Rapid Sedation of Agitated Patients in the Prehospital and Emergency Department Settings: A Systematic Review and Proportional Meta-Analysis. ( Cole, JB; Kaldan, J; Mankowitz, SL; Regenberg, P, 2018) |
| " It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia." | 2.48 | Ketamine, propofol, and ketofol use for pediatric sedation. ( Alletag, MJ; Auerbach, MA; Baum, CR, 2012) |
| " We sought to measure the frequency of ED intubation at a Midwest academic medical center after prehospital ketamine use for profound agitation, hypothesizing that intubation has become less frequent as prehospital ketamine has become more common and prehospital dosing has improved." | 1.62 | Outcomes Associated with Lower Doses of Ketamine by Emergency Medical Services for Profound Agitation. ( Ahmed, A; Coffey, SK; Egan, H; Harland, KK; Mohr, NM; Vakkalanka, JP; Wallace, K, 2021) |
| "Background Psychomotor agitation can be problematic in an overcrowded emergency department (ED) during uncontrolled procedural sedation." | 1.51 | Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia. ( Akbari, H; Bahreini, M; Jalali, A, 2019) |
| "Ketamine is an emerging drug used in the management of undifferentiated, severe agitation in the prehospital setting." | 1.51 | Psychiatric Outcomes of Patients With Severe Agitation Following Administration of Prehospital Ketamine. ( Akhavan, AR; Gittinger, MH; Hippe, DS; Lebin, JA; McCoy, AM; Pasic, J; Vrablik, MC, 2019) |
| "Ketamine is a noncompetitive N-methyl-D-aspartic acid receptor antagonist, making it an effective dissociative agent." | 1.46 | A Novel Agent for Management of Agitated Delirium: A Case Series of Ketamine Utilization in the Pediatric Emergency Department. ( Kopec, KT; Kowalski, JM; Lavelle, J; Osterhoudt, K, 2017) |
| "Ketamine is an emerging drug for the treatment of acute undifferentiated agitation in the prehospital environment, however no prospective comparative studies have evaluated its effectiveness or safety in this clinical setting." | 1.43 | A prospective study of ketamine versus haloperidol for severe prehospital agitation. ( Bache-Wiig, P; Cole, JB; Engebretsen, KM; Fryza, BJ; Ho, JD; Kornas, RL; Moore, JC; Nystrom, PC; O'Brien-Lambert, A; Orozco, BS; Steinberg, LW; Stellpflug, SJ, 2016) |
| "Prehospital ketamine is associated with a high rate of endotracheal intubation in profoundly agitated patients; however, ketamine dosing is not associated with intubation rate when adjusted for potential confounders." | 1.43 | Intubation of Profoundly Agitated Patients Treated with Prehospital Ketamine. ( Cole, JB; Dodd, KW; Ho, JD; Nystrom, PC; Olives, TD, 2016) |
| "Ketamine was administered for agitation on 32 visits involving 27 patients." | 1.42 | Ketamine use for acute agitation in the emergency department. ( Campillo, A; Castillo, EM; Davie, T; Hopper, AB; Vilke, GM; Wilson, MP, 2015) |
| "Ketamine is an effective agent for procedural sedation in the emergency department." | 1.35 | Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study. ( Fitton, L; Newton, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.74) | 18.7374 |
| 1990's | 2 (2.74) | 18.2507 |
| 2000's | 10 (13.70) | 29.6817 |
| 2010's | 43 (58.90) | 24.3611 |
| 2020's | 16 (21.92) | 2.80 |
| Authors | Studies |
|---|---|
| Coffey, SK | 1 |
| Vakkalanka, JP | 1 |
| Egan, H | 1 |
| Wallace, K | 1 |
| Harland, KK | 1 |
| Mohr, NM | 1 |
| Ahmed, A | 1 |
| deSouza, IS | 1 |
| Thode, HC | 1 |
| Shrestha, P | 1 |
| Allen, R | 1 |
| Koos, J | 1 |
| Singer, AJ | 1 |
| Chueh, KS | 1 |
| Huang, KH | 1 |
| Lu, JH | 1 |
| Juan, TJ | 1 |
| Chuang, SM | 1 |
| Lin, RJ | 1 |
| Lee, YC | 1 |
| Long, CY | 1 |
| Shen, MC | 1 |
| Sun, TW | 1 |
| Juan, YS | 1 |
| Krenz, JR | 1 |
| Medeiros, K | 1 |
| Lupez, K | 1 |
| Wolfe, C | 1 |
| McCoin, N | 1 |
| Springer, B | 1 |
| Jalali, A | 1 |
| Akbari, H | 1 |
| Bahreini, M | 1 |
| Sullivan, N | 1 |
| Chen, C | 1 |
| Siegel, R | 1 |
| Ma, Y | 1 |
| Pourmand, A | 1 |
| Montano, N | 1 |
| Meltzer, A | 1 |
| Lin, J | 1 |
| Figuerado, Y | 1 |
| Montgomery, A | 1 |
| Lee, J | 1 |
| Cannis, M | 1 |
| Norton, VC | 1 |
| Calvo, R | 1 |
| Sikand, H | 1 |
| McIntyre, RS | 1 |
| Lipsitz, O | 1 |
| Rodrigues, NB | 1 |
| Lee, Y | 1 |
| Cha, DS | 1 |
| Vinberg, M | 1 |
| Lin, K | 1 |
| Malhi, GS | 1 |
| Subramaniapillai, M | 1 |
| Kratiuk, K | 1 |
| Fagiolini, A | 1 |
| Gill, H | 1 |
| Nasri, F | 1 |
| Mansur, RB | 1 |
| Suppes, T | 1 |
| Ho, R | 1 |
| Rosenblat, JD | 1 |
| Parks, DJ | 1 |
| Alter, SM | 1 |
| Shih, RD | 1 |
| Solano, JJ | 1 |
| Hughes, PG | 1 |
| Clayton, LM | 1 |
| Kim, HK | 1 |
| Leonard, JB | 1 |
| Corwell, BN | 1 |
| Connors, NJ | 1 |
| Cunningham, C | 1 |
| Gross, K | 1 |
| Broach, JP | 1 |
| O'Connor, L | 1 |
| Bernard, S | 1 |
| Roggenkamp, R | 1 |
| Delorenzo, A | 1 |
| Stephenson, M | 1 |
| Smith, K | 1 |
| Zhang, F | 1 |
| Hillhouse, TM | 1 |
| Anderson, PM | 1 |
| Koppenhaver, PO | 1 |
| Kegen, TN | 1 |
| Manicka, SG | 1 |
| Lane, JT | 1 |
| Pottanat, E | 1 |
| Van Fossen, M | 1 |
| Rice, R | 1 |
| Porter, JH | 1 |
| Barbic, D | 2 |
| Andolfatto, G | 2 |
| Grunau, B | 2 |
| Scheuermeyer, FX | 2 |
| Macewan, B | 1 |
| Qian, H | 1 |
| Wong, H | 2 |
| Barbic, SP | 2 |
| Honer, WG | 2 |
| Azizkhani, R | 1 |
| Kouhestani, S | 1 |
| Heydari, F | 1 |
| Majidinejad, S | 1 |
| Lee, A | 1 |
| Bhullar, IS | 1 |
| Gonin, P | 1 |
| Beysard, N | 1 |
| Yersin, B | 1 |
| Carron, PN | 1 |
| Cole, JB | 5 |
| Klein, LR | 2 |
| Nystrom, PC | 4 |
| Moore, JC | 3 |
| Driver, BE | 2 |
| Fryza, BJ | 2 |
| Harrington, J | 1 |
| Ho, JD | 4 |
| Linder, LM | 1 |
| Ross, CA | 1 |
| Weant, KA | 1 |
| Miner, JR | 1 |
| Gottlieb, M | 1 |
| Long, B | 1 |
| Koyfman, A | 1 |
| Steenblock, D | 1 |
| Hurwitz, J | 1 |
| Abdel-Ghaffar, HS | 1 |
| Kamal, SM | 1 |
| El Sherif, FA | 1 |
| Mohamed, SA | 1 |
| Mankowitz, SL | 1 |
| Regenberg, P | 1 |
| Kaldan, J | 1 |
| MacEwan, W | 1 |
| Tian, LL | 1 |
| Newman, WJ | 1 |
| Lebin, JA | 1 |
| Akhavan, AR | 1 |
| Hippe, DS | 1 |
| Gittinger, MH | 1 |
| Pasic, J | 1 |
| McCoy, AM | 1 |
| Vrablik, MC | 1 |
| Tan, D | 1 |
| Xia, H | 1 |
| Sun, S | 1 |
| Wang, F | 1 |
| Rosen, HD | 1 |
| Cravero, JP | 1 |
| Bilgen, S | 1 |
| Köner, Ö | 1 |
| Karacay, S | 1 |
| Sancar, NK | 1 |
| Kaspar, EC | 1 |
| Sözübir, S | 1 |
| Scheppke, KA | 1 |
| Braghiroli, J | 1 |
| Shalaby, M | 1 |
| Chait, R | 1 |
| Schultz, CH | 2 |
| Hadi, SM | 1 |
| Saleh, AJ | 1 |
| Tang, YZ | 1 |
| Daoud, A | 1 |
| Mei, X | 1 |
| Ouyang, W | 1 |
| Hopper, AB | 1 |
| Vilke, GM | 1 |
| Castillo, EM | 1 |
| Campillo, A | 1 |
| Davie, T | 1 |
| Wilson, MP | 1 |
| Moitra, VK | 1 |
| Patel, MK | 1 |
| Darrah, D | 1 |
| Moitra, A | 1 |
| Wunsch, H | 1 |
| Kowalski, JM | 1 |
| Kopec, KT | 1 |
| Lavelle, J | 1 |
| Osterhoudt, K | 1 |
| Normandin, PA | 1 |
| Khorey, SJ | 1 |
| Donahue, MA | 1 |
| Benotti, SA | 1 |
| Manning, BA | 1 |
| Kidd, LR | 1 |
| Lyons, SC | 1 |
| Lloyd, G | 1 |
| Strote, J | 1 |
| Vincent, JL | 1 |
| Shehabi, Y | 1 |
| Walsh, TS | 1 |
| Pandharipande, PP | 1 |
| Ball, JA | 1 |
| Spronk, P | 1 |
| Longrois, D | 1 |
| Strøm, T | 1 |
| Conti, G | 1 |
| Funk, GC | 1 |
| Badenes, R | 1 |
| Mantz, J | 1 |
| Spies, C | 1 |
| Takala, J | 1 |
| Orozco, BS | 1 |
| Stellpflug, SJ | 1 |
| Kornas, RL | 1 |
| Steinberg, LW | 1 |
| O'Brien-Lambert, A | 1 |
| Bache-Wiig, P | 1 |
| Engebretsen, KM | 1 |
| Vrana, B | 1 |
| Olives, TD | 1 |
| Dodd, KW | 1 |
| Riddell, J | 1 |
| Tran, A | 1 |
| Bengiamin, R | 1 |
| Hendey, GW | 1 |
| Armenian, P | 1 |
| Newton, A | 1 |
| Fitton, L | 1 |
| Green, SM | 1 |
| Roback, MG | 1 |
| Krauss, B | 1 |
| Brown, L | 1 |
| McGlone, RG | 1 |
| Agrawal, D | 1 |
| McKee, M | 1 |
| Weiss, M | 1 |
| Pitetti, RD | 1 |
| Hostetler, MA | 1 |
| Wathen, JE | 1 |
| Treston, G | 1 |
| Garcia Pena, BM | 1 |
| Gerber, AC | 1 |
| Losek, JD | 1 |
| Wood, DM | 1 |
| Looker, JJ | 1 |
| Shaikh, L | 1 |
| Button, J | 1 |
| Puchnarewicz, M | 1 |
| Davies, S | 1 |
| Lidder, S | 1 |
| Ramsey, J | 1 |
| Holt, DW | 1 |
| Dargan, PI | 1 |
| Khattab, AM | 1 |
| El-Seify, ZA | 1 |
| Shaaban, A | 1 |
| Radojevic, D | 1 |
| Jankovic, I | 1 |
| Chen, J | 1 |
| Li, W | 1 |
| Hu, X | 1 |
| Wang, D | 1 |
| Sener, S | 1 |
| Eken, C | 1 |
| Serinken, M | 1 |
| Ozsarac, M | 1 |
| Eich, C | 1 |
| Verhagen-Henning, S | 1 |
| Roessler, M | 1 |
| Cremer, F | 1 |
| Cremer, S | 1 |
| Strack, M | 1 |
| Russo, SG | 1 |
| Bauchat, JR | 1 |
| Higgins, N | 1 |
| Wojciechowski, KG | 1 |
| McCarthy, RJ | 1 |
| Toledo, P | 1 |
| Wong, CA | 1 |
| Le Cong, M | 1 |
| Gynther, B | 1 |
| Hunter, E | 1 |
| Schuller, P | 1 |
| Anghelescu, DL | 1 |
| Rakes, LC | 1 |
| Shearer, JR | 1 |
| Bikhazi, GB | 1 |
| Chatterjee, M | 1 |
| Singh, S | 1 |
| Kumari, R | 1 |
| Verma, AK | 1 |
| Palit, G | 1 |
| Kranaster, L | 1 |
| Janke, C | 1 |
| Hoyer, C | 1 |
| Sartorius, A | 1 |
| Alletag, MJ | 1 |
| Auerbach, MA | 1 |
| Baum, CR | 1 |
| Chen, JY | 1 |
| Jia, JE | 1 |
| Liu, TJ | 1 |
| Qin, MJ | 1 |
| Li, WX | 1 |
| Kawaraguchi, Y | 2 |
| Miyamoto, Y | 1 |
| Fukumitsu, K | 1 |
| Taniguchi, A | 1 |
| Hirao, O | 1 |
| Kitamura, S | 1 |
| Kinouchi, K | 1 |
| Kararmaz, A | 1 |
| Kaya, S | 1 |
| Turhanoglu, S | 1 |
| Ozyilmaz, MA | 1 |
| Horiuchi, T | 1 |
| Kawaguchi, M | 1 |
| Kurehara, K | 1 |
| Sasaoka, N | 1 |
| Furuya, H | 1 |
| Dalens, BJ | 1 |
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| Erk, G | 1 |
| Ornek, D | 1 |
| Dönmez, NF | 1 |
| Taşpinar, V | 1 |
| Abu-Shahwan, I | 1 |
| Chowdary, K | 1 |
| Aouad, MT | 1 |
| Moussa, AR | 1 |
| Dagher, CM | 1 |
| Muwakkit, SA | 1 |
| Jabbour-Khoury, SI | 1 |
| Zbeidy, RA | 1 |
| Abboud, MR | 1 |
| Kanazi, GE | 1 |
| Geist, ET | 1 |
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| Warner, DL | 1 |
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| Venturini, AH | 1 |
| Parietti, A | 1 |
| Giménez, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| Premedication With Different Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children[NCT02935959] | Phase 1/Phase 2 | 90 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural Sedation: a Randomized Controlled Trial[NCT04822064] | 70 participants (Anticipated) | Interventional | 2022-09-22 | Recruiting | |||
| Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children: a Randomized Controlled Trial[NCT04820205] | 136 participants (Anticipated) | Interventional | 2021-09-03 | Recruiting | |||
| Rapid Agitation Control With Ketamine in the Emergency Department (RACKED): a Randomized Controlled Trial[NCT03375671] | Phase 2 | 81 participants (Actual) | Interventional | 2018-05-29 | Completed | ||
| Comparison of Ketamine 0.1 mg/kg, 0.2 mg/kg, and 0.3 mg/kg Intravenous Doses for Acute Pain in the Emergency Department: A Prospective, Randomized, Double-blind, Active-controlled, Clinical Trial[NCT03896230] | Phase 4 | 11 participants (Actual) | Interventional | 2019-05-03 | Terminated (stopped due to Due to resource limitations the study was on hold and was then terminated.) | ||
| Emergence Delirium in Children: a Randomized Clinical Trial of Different Doses of Sevoflurane During Induction of Anesthesia[NCT02707016] | 80 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| KETODEX for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery[NCT03779282] | 90 participants (Actual) | Observational | 2018-02-15 | Completed | |||
| ED Treatment of Suicidal Patients With Ketamine Infusion[NCT03502551] | Phase 2 | 0 participants (Actual) | Interventional | 2019-04-01 | Withdrawn (stopped due to Trial never received funding.) | ||
| Epidemiology of Weaning From Invasive Mechanical Ventilation in COVID-19. Observational and Multicenter Study.[NCT05049200] | 326 participants (Actual) | Observational [Patient Registry] | 2020-04-01 | Completed | |||
| Southern Medical University Clinical Research Project Initiative：Efficacy and Safety of a Multicomponent Physical Therapy Program in Mechanically Ventilated Patient With Sepsis[NCT03406494] | 800 participants (Anticipated) | Interventional | 2018-03-31 | Not yet recruiting | |||
| Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion[NCT03751423] | Phase 3 | 123 participants (Anticipated) | Interventional | 2019-06-10 | Suspended (stopped due to Study on-hold due to COVID-19 pandemic restrictions. Will resume when possible.) | ||
| A Comparison of Midazolam or Haloperidol Premedication Versus Placebo for Reducing Ketamine Induced Agitation After Adult Procedural Sedation in the Emergency Department[NCT02909465] | Phase 4 | 185 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy[NCT02643979] | Phase 4 | 22 participants (Actual) | Interventional | 2016-01-01 | Terminated (stopped due to Lack of Enrollment) | ||
| Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine[NCT04746079] | 180 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | |||
| [NCT01506622] | 222 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| Efficacy and Safety of Esketamine or Sevoflurane Add to Dexmedetomidine-based Sedation for Ophthalmology Procedure in Children[NCT05321160] | 116 participants (Actual) | Interventional | 2021-03-10 | Completed | |||
| Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries: A Randomized Clinical Trial[NCT03470675] | Phase 4 | 67 participants (Actual) | Interventional | 2018-06-27 | Active, not recruiting | ||
| Effect of Intravenous Nalbuphine on Emergence Agitation in Children Undergoing Repair of Rupture Globe[NCT03470077] | Phase 2 | 80 participants (Actual) | Interventional | 2019-07-31 | Completed | ||
| Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)[NCT02422290] | Phase 1/Phase 2 | 5 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Frequency of adverse events secondary to ketamine including fatigue, dizziness, nausea, headache, feeling of unreality, changes in hearing or vision, mood changes, generalized discomfort, and hallucinations, changes in vital signs.~Adverse events were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| at 15 min post infusion | at 30 min post infusion | at 60 min post infusion | at 90 min post infusion | at 120 min post infusion | |
| Arm 1: 0.1 mg/kg Ketamine | 2 | 1 | 1 | 1 | 1 |
| Arm 1: 0.2 mg/kg Ketamine | 3 | 2 | 2 | 2 | 0 |
| Arm 1: 0.3 mg/kg Ketamine | 2 | 1 | 0 | 0 | 0 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | |
| Arm 1: 0.3 mg/kg Ketamine | 7.5 | 2 | 6 | 5 | 2 |
| Arm 1: 0.2 mg/kg Ketamine | 8.5 | 6 | 5.75 | 7 | 7 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | Pain score at 120 min | |
| Arm 1: 0.1 mg/kg Ketamine | 9.4 | 5.25 | 5.25 | 5.25 | 4.5 | 4 |
The Anesthesiologist caring for the patient during the upper endoscopy made note of any obstructive events defined on a scale ranging from the patient audibly snoring (obstructing) to the patient obstructing and requiring assistance such as a chin lift or jaw thrust to relieve the obstruction and continue to move air adequately. (NCT02643979)
Timeframe: Day 1
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketofol: Ketamine and Propofol | 4 |
| Propofol Only | 3 |
Number of participants with emergence delirium measured from the procedure end until time of discharge. (NCT02643979)
Timeframe: Day 1
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketofol: Ketamine and Propofol | 0 |
| Propofol Only | 0 |
"Number of participants with gagging or vomit-like reaction on endoscopic insertion" (NCT02643979)
Timeframe: Day 1
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketofol: Ketamine and Propofol | 2 |
| Propofol Only | 1 |
(NCT02643979)
Timeframe: up to 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketofol: Ketamine and Propofol | 0 |
| Propofol Only | 0 |
Monitored via the electronic medical record system as the time between the anesthesia end time and when the patient was safe for discharge from the hospital. (NCT02643979)
Timeframe: Day 1
| Intervention | minutes (Mean) |
|---|---|
| Ketofol: Ketamine and Propofol | 21 |
| Propofol Only | 25 |
Propofol doses are logged in the computerized Compurecord system used in the operating room. Patients involved in the study had their total Propofol dose required quantified and compared between groups who received Ketamine and groups who did not. (NCT02643979)
Timeframe: Day 1
| Intervention | mg/kg (Mean) |
|---|---|
| Ketofol: Ketamine and Propofol | 9.09 |
| Propofol Only | 39 |
Using the computerized record system, the amount of Propofol a patient required to allow for the procedure to start quantified and compared between groups. (NCT02643979)
Timeframe: Day 1
| Intervention | mg/kg (Mean) |
|---|---|
| Ketofol: Ketamine and Propofol | 78 |
| Propofol Only | 61 |
The CY-BOCS is a semi-structured measure of OCD severity with excellent inter-rater reliability, internal consistency, and test-retest reliability. It is validated in those starting at age 7 and used in studies up to age 20. The CYBOCS differs from the adult YBOCS only in its use of simpler language. The CY-BOCS consists of 10 items which are summed up to derive the total CY-BOCS score. The total score ranges from 0-40 with higher scores indicating greater severity of OCD symptoms. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| CY-BOCS Baseline | CY-BOCS Day 14 | |
| Ketamine Treatment Group | 29.00 | 26.20 |
The CGI-S is a clinician rated 7-point rating scale for the severity of a participant's illness relative to the clinician's experience of working with this particular population. The score ranges from 1-7 with higher scores indicating greater illness severity. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| CGI-S Baseline | CGI-S Day 14 | |
| Ketamine Treatment Group | 5.80 | 5.00 |
"The OCD-VAS is a one-item unipolar scale to assess OCD symptoms over a rapid time frame (No obsessions to Constant obsessions). The scale ranges from 0-10 with higher scores indicating higher presence of obsessions." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| OCD-VAS Baseline | OCD-VAS Day 14 | |
| Ketamine Treatment Group | 5.00 | 5.00 |
"The Y-BOCCS is self-report scale which assesses OCD symptoms on a 5-point likert scale (None to Extreme). It consists of 10 items which are summed up to derive the total Y-BOCCS score. The total score ranges from 0-40 with higher scores indicating higher prevalence of OCD symptoms." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Y-BOCCS Baseline | Y-BOCCS Day 14 | |
| Ketamine Treatment Group | 18.25 | 16.50 |
14 reviews available for ketamine and Psychomotor Agitation
| Article | Year |
|---|---|
Rapid tranquilization of the agitated patient in the emergency department: A systematic review and network meta-analysis.
Topics: Adult; Droperidol; Emergence Delirium; Emergency Service, Hospital; Humans; Ketamine; Network Meta-A | 2022 |
Management of the Agitated Patient.
Topics: Antipsychotic Agents; Benzodiazepines; Emergency Service, Hospital; Humans; Ketamine; Psychomotor Ag | 2024 |
Hyperactive Delirium with Severe Agitation.
Topics: Delirium; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; Ketamine; Psychomotor Agitat | 2024 |
Ketamine for emergency sedation of agitated patients: A systematic review and meta-analysis.
Topics: Airway Management; Anesthesia; Anesthetics, Dissociative; Emergencies; Emergency Medical Services; H | 2020 |
Safety and efficacy of pharmacologic agents used for rapid tranquilization of emergency department patients with acute agitation or excited delirium.
Topics: Acute Disease; Aggression; Antipsychotic Agents; Benzodiazepines; Delirium; Emergency Service, Hospi | 2021 |
Intravenous Ketamine for Agitation in Critical Care.
Topics: Adult; Burns; Critical Care; Follow-Up Studies; Humans; Infusions, Intravenous; Injury Severity Scor | 2017 |
Excited Delirium: A Systematic Review.
Topics: Antipsychotic Agents; Delirium; Female; Humans; Ketamine; Male; Psychomotor Agitation; Retrospective | 2018 |
Ketamine for the Acute Management of Excited Delirium and Agitation in the Prehospital Setting.
Topics: Algorithms; Delirium; Emergency Medical Services; Excitatory Amino Acid Antagonists; Humans; Ketamin | 2018 |
Ketamine for Rapid Sedation of Agitated Patients in the Prehospital and Emergency Department Settings: A Systematic Review and Proportional Meta-Analysis.
Topics: Anesthetics, Dissociative; Emergency Service, Hospital; Humans; Ketamine; Psychomotor Agitation | 2018 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theo | 2019 |
Use of Intranasal Ketamine for the Severely Agitated or Violent ED Patient.
Topics: Administration, Intranasal; Analgesics; Emergency Nursing; Emergency Service, Hospital; Humans; Keta | 2016 |
Comfort and patient-centred care without excessive sedation: the eCASH concept.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Critical Care; Deep Sedation; De | 2016 |
Comfort and patient-centred care without excessive sedation: the eCASH concept.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Critical Care; Deep Sedation; De | 2016 |
Comfort and patient-centred care without excessive sedation: the eCASH concept.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Critical Care; Deep Sedation; De | 2016 |
Comfort and patient-centred care without excessive sedation: the eCASH concept.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Critical Care; Deep Sedation; De | 2016 |
Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data meta-analysis of 8,282 children.
Topics: Age Factors; Anesthesia Recovery Period; Anesthetics, Dissociative; Benzodiazepines; Child; Child, P | 2009 |
Ketamine, propofol, and ketofol use for pediatric sedation.
Topics: Adolescent; Amnesia; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Antiemetics; An | 2012 |
20 trials available for ketamine and Psychomotor Agitation
| Article | Year |
|---|---|
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Anti-Anxiety Agents; Antipsychotic Agents | 2021 |
Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial.
Topics: Adult; Anesthetics, Dissociative; Canada; Female; Haloperidol; Humans; Hypnotics and Sedatives; Inje | 2021 |
A comparative study of dexmedetomidine and propofol to prevent recovery agitation in adults undergoing procedural sedation with ketamine: A randomized double-blind clinical trial.
Topics: Adult; Anesthetics, Dissociative; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Emergenc | 2021 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination | 2018 |
Rapid agitation control with ketamine in the emergency department (RACKED): a randomized controlled trial protocol.
Topics: Adult; Anesthetics, Dissociative; British Columbia; Emergency Service, Hospital; Female; Haloperidol | 2018 |
Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: a prospective randomized clinical trial.
Topics: Alfentanil; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Drug Thera | 2014 |
The effect of KETODEX on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane based-anesthesia.
Topics: Adenoidectomy; Adrenergic alpha-2 Receptor Agonists; Airway Extubation; Anesthesia Recovery Period; | 2015 |
The effect of KETODEX on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane based-anesthesia.
Topics: Adenoidectomy; Adrenergic alpha-2 Receptor Agonists; Airway Extubation; Anesthesia Recovery Period; | 2015 |
The effect of KETODEX on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane based-anesthesia.
Topics: Adenoidectomy; Adrenergic alpha-2 Receptor Agonists; Airway Extubation; Anesthesia Recovery Period; | 2015 |
The effect of KETODEX on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane based-anesthesia.
Topics: Adenoidectomy; Adrenergic alpha-2 Receptor Agonists; Airway Extubation; Anesthesia Recovery Period; | 2015 |
Emergence agitation after cataract surgery in children: a comparison of midazolam, propofol and ketamine.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; | 2010 |
Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial.
Topics: Adult; Analgesics; Conscious Sedation; Double-Blind Method; Drug Therapy, Combination; Emergency Ser | 2011 |
Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial.
Topics: Adult; Analgesics; Conscious Sedation; Double-Blind Method; Drug Therapy, Combination; Emergency Ser | 2011 |
Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial.
Topics: Adult; Analgesics; Conscious Sedation; Double-Blind Method; Drug Therapy, Combination; Emergency Ser | 2011 |
Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial.
Topics: Adult; Analgesics; Conscious Sedation; Double-Blind Method; Drug Therapy, Combination; Emergency Ser | 2011 |
Low-dose ketamine with multimodal postcesarean delivery analgesia: a randomized controlled trial.
Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal | 2011 |
Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children.
Topics: Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Inhalation; Child; Child, Presch | 2013 |
[The effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in pediatric strabismus surgery].
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Combined; Child; Child, Preschool; | 2002 |
Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia.
Topics: Adenoidectomy; Administration, Oral; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, In | 2004 |
Evaluation of relatively low dose of oral transmucosal ketamine premedication in children: a comparison with oral midazolam.
Topics: Administration, Buccal; Anesthesia, Inhalation; Anesthetics, Dissociative; Anxiety, Separation; Chil | 2005 |
Prevention of emergence agitation after sevoflurane anesthesia for pediatric cerebral magnetic resonance imaging by small doses of ketamine or nalbuphine administered just before discontinuing anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Brain; Chi-Square Distribution; Humans; Infant; | 2006 |
The use of ketamine or ketamine-midazolam for adenotonsillectomy.
Topics: Adenoidectomy; Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Atropin | 2007 |
Ketamine is effective in decreasing the incidence of emergence agitation in children undergoing dental repair under sevoflurane general anesthesia.
Topics: Anesthesia, Dental; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Child; | 2007 |
Addition of ketamine to propofol for initiation of procedural anesthesia in children reduces propofol consumption and preserves hemodynamic stability.
Topics: Adolescent; Analgesics; Anesthesia; Anesthetics, Intravenous; Biopsy, Needle; Blood Pressure; Child; | 2008 |
Ketamine plus midazolam, a most effective paediatric oral premedicant.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia, Inhalation; Anesthetics, Dissociative; Anxi | 1995 |
[Flunitrazepam (Ro 5-4200): a new benzodiazepinic derivative. Comparative double blind study with diazepam to control the psychomotor reactions of ketamine].
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anti-Anxiety Agents; Diazepam; Dilatation and Cure | 1977 |
39 other studies available for ketamine and Psychomotor Agitation
| Article | Year |
|---|---|
Outcomes Associated with Lower Doses of Ketamine by Emergency Medical Services for Profound Agitation.
Topics: Adult; Analgesics; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Emergency Medical Se | 2021 |
Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model.
Topics: Animals; Cystitis; Female; Humans; Ketamine; Platelet-Rich Plasma; Psychomotor Agitation; Rats; Rats | 2022 |
Retrospective evaluation of ketamine versus droperidol on time to restraint removal in agitated emergency department patients.
Topics: Bradycardia; Droperidol; Emergency Service, Hospital; Humans; Ketamine; Psychomotor Agitation; Respi | 2023 |
Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia.
Topics: Analgesia; Analgesics; Conscious Sedation; Emergency Service, Hospital; Humans; Injections, Intramus | 2019 |
The effectiveness of ketamine on anxiety, irritability, and agitation: Implications for treating mixed features in adults with major depressive or bipolar disorder.
Topics: Adult; Anxiety; Bipolar Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resista | 2020 |
Rescue Intubation in the Emergency Department After Prehospital Ketamine Administration for Agitation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Cohort Studies; Emergency Med | 2020 |
Patient Outcomes Following Ketamine Administration for Acute Agitation with a Decreased Dosing Protocol in the Prehospital Setting.
Topics: Adult; Emergency Service, Hospital; Female; Humans; Injections, Intramuscular; Ketamine; Male; Psych | 2021 |
Use of intramuscular ketamine by paramedics in the management of severely agitated patients.
Topics: Adult; Allied Health Personnel; Female; Humans; Ketamine; Male; Prospective Studies; Psychomotor Agi | 2021 |
Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice.
Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; E | 2021 |
A prospective study of ketamine as primary therapy for prehospital profound agitation.
Topics: Adult; Aged; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Emergency Medical Services | 2018 |
In reply: Ketamine is an important therapy for prehospital agitation - Its exact role and side effect profile are still undefined.
Topics: Anesthetics, Dissociative; Humans; Ketamine; Psychomotor Agitation | 2018 |
Ketamine is a good first-line option for severely agitated patients in the prehospital environment.
Topics: Anesthetics, Dissociative; Emergency Medical Services; Humans; Ketamine; Psychomotor Agitation | 2018 |
Approach to the Agitated Emergency Department Patient.
Topics: Anesthetics, Dissociative; Antipsychotic Agents; Benzodiazepines; Disease Management; Emergency Serv | 2018 |
Treatment of Behavior Disturbances with Ketamine in a Patient Diagnosed with Major Neurocognitive Disorder.
Topics: Aged; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intramuscular; Ketamine; Neuroc | 2018 |
Can We Finally Dispense With Ketamine's Many Myths?
Topics: Anesthetics, Dissociative; Antidepressive Agents; Drug-Related Side Effects and Adverse Reactions; E | 2018 |
Psychiatric Considerations Regarding Prehospital Administration of Ketamine for Agitation.
Topics: Conscious Sedation; Emergency Medical Services; Humans; Hypnotics and Sedatives; Ketamine; Male; Psy | 2019 |
Psychiatric Outcomes of Patients With Severe Agitation Following Administration of Prehospital Ketamine.
Topics: Administration, Intravenous; Adult; Anesthetics, Dissociative; Benzodiazepines; Emergency Medical Se | 2019 |
Research on emergence agitation in children.
Topics: Dexmedetomidine; Female; Humans; Ketamine; Male; Psychomotor Agitation; Strabismus | 2013 |
Prehospital use of i.m. ketamine for sedation of violent and agitated patients.
Topics: Anesthetics, Dissociative; Dangerous Behavior; Delirium; Emergency Medical Services; Emergency Medic | 2014 |
Prehospital use of i.m. ketamine for sedation of violent and agitated patients.
Topics: Anesthetics, Dissociative; Dangerous Behavior; Delirium; Emergency Medical Services; Emergency Medic | 2014 |
Prehospital use of i.m. ketamine for sedation of violent and agitated patients.
Topics: Anesthetics, Dissociative; Dangerous Behavior; Delirium; Emergency Medical Services; Emergency Medic | 2014 |
Prehospital use of i.m. ketamine for sedation of violent and agitated patients.
Topics: Anesthetics, Dissociative; Dangerous Behavior; Delirium; Emergency Medical Services; Emergency Medic | 2014 |
Ketamine for pre-hospital control of agitated delirious patients: promising but not yet ready for prime time.
Topics: Anesthetics, Dissociative; Delirium; Emergency Medical Services; Emergency Medical Technicians; Huma | 2014 |
Ketamine use for acute agitation in the emergency department.
Topics: Adult; Aged; Aggression; Alcoholic Intoxication; Anesthetics, Dissociative; Antipsychotic Agents; Be | 2015 |
Low-Dose Ketamine in Chronic Critical Illness.
Topics: Analgesics; Anxiety; Chronic Disease; Critical Care; Critical Illness; Dose-Response Relationship, D | 2016 |
A Novel Agent for Management of Agitated Delirium: A Case Series of Ketamine Utilization in the Pediatric Emergency Department.
Topics: Adolescent; Anesthetics, Dissociative; Delirium; Emergency Service, Hospital; Female; Humans; Inject | 2017 |
Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review of practice.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Databases, Factu | 2016 |
Caution When Using the Term and Diagnosis of Agitated Delirium.
Topics: Delirium; Diagnostic Errors; Emergency Service, Hospital; Humans; Ketamine; Psychomotor Agitation; R | 2016 |
A prospective study of ketamine versus haloperidol for severe prehospital agitation.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dose-Response Relationship, Drug; Emergency Service, | 2016 |
Use of Intranasal Ketamine for the Severely Agitated or Violent ED Patient.
Topics: Analgesics; Humans; Ketamine; Psychomotor Agitation | 2016 |
Intubation of Profoundly Agitated Patients Treated with Prehospital Ketamine.
Topics: Adult; Emergency Medical Services; Excitatory Amino Acid Antagonists; Female; Humans; Intubation, In | 2016 |
Ketamine as a first-line treatment for severely agitated emergency department patients.
Topics: Adolescent; Adult; Anesthetics, Dissociative; California; Conscious Sedation; Dose-Response Relation | 2017 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Conscious Sedation; Dose-Response Relations | 2008 |
Delayed onset of seizures and toxicity associated with recreational use of Bromo-dragonFLY.
Topics: Adolescent; Benzodiazepines; Bromobenzoates; Chromatography, Liquid; Chromatography, Thin Layer; Cri | 2009 |
Sevoflurane-emergence agitation: effect of supplementary low-dose oral ketamine premedication in preschool children undergoing dental surgery.
Topics: Administration, Oral; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2010 |
Low-dose S-ketamine added to propofol anesthesia for magnetic resonance imaging in children is safe and ensures faster recovery--a prospective evaluation.
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Child, Preschoo | 2011 |
Ketamine sedation for patients with acute agitation and psychiatric illness requiring aeromedical retrieval.
Topics: Acute Disease; Adolescent; Adult; Air Ambulances; Anesthetics, Dissociative; Child; Female; Humans; | 2012 |
Prevention of emergence agitation in seven children receiving low-dose ketamine and propofol total intravenous anesthesia.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Child, Preschool; Drug Interactions; Humans; In | 2011 |
Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Ketamine; Male; | 2012 |
Management of severe postictal agitation after electroconvulsive therapy with bispectrum electroencephalogram index monitoring: a case report.
Topics: Aged; Anesthesia; Anesthetics, Dissociative; Consciousness Monitors; Depressive Disorder, Major; Ele | 2012 |
Reduction of ketamine-induced emergence phenomena by preoperative promethazine.
Topics: Child; Child, Preschool; Double-Blind Method; Hallucinations; Humans; Ketamine; Nausea; Promethazine | 1982 |
Intramuscular ketamine, midazolam, and glycopyrrolate for pediatric sedation in the emergency department.
Topics: Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Dissociative; Child; Child Behavior; Ch | 1995 |