ketamine has been researched along with Osteoarthritis in 4 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study evaluated the effect of intra-articular injections of ketamine and 25% dextrose with triamcinolone acetate (TA) and hyaluronic acid (HA) on joint pathology and pain behavior in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in experimental mice." | 7.85 | Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis. ( Brahma, S; Jalgaonkar, SV; Koli, PG; Kshirsagar, S; Patil, AE; Rege, NN; Salgaonkar, S; Shetty, YC; Teltumbde, PA, 2017) |
| "The aim of the present study was to investigate the efficacy of ketamine in attenuating osteoarthritis (OA) and modulating the expression of inflammatory mediators." | 7.83 | Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model. ( Lu, W; Wang, L; Wo, C; Yao, J, 2016) |
| " Osteoarthritis was induced in male adult control Wistar rats without any interventions and in Wisket rats after juvenile social isolation and ketamine treatment." | 3.96 | Distinct changes in chronic pain sensitivity and oxytocin receptor expression in a new rat model (Wisket) of schizophrenia. ( Banki, L; Büki, A; Horvath, G; Jancsó, G; Kekesi, G; Kis, G; Somogyvári, F; Tuboly, G; Varga, E; Vécsei, L, 2020) |
| "The study evaluated the effect of intra-articular injections of ketamine and 25% dextrose with triamcinolone acetate (TA) and hyaluronic acid (HA) on joint pathology and pain behavior in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in experimental mice." | 3.85 | Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis. ( Brahma, S; Jalgaonkar, SV; Koli, PG; Kshirsagar, S; Patil, AE; Rege, NN; Salgaonkar, S; Shetty, YC; Teltumbde, PA, 2017) |
| "The aim of the present study was to investigate the efficacy of ketamine in attenuating osteoarthritis (OA) and modulating the expression of inflammatory mediators." | 3.83 | Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model. ( Lu, W; Wang, L; Wo, C; Yao, J, 2016) |
| "Our report describes for the first time the continuous long-term intrathecal application of S(+)-ketamine in a patient with chronic pain and morphine tolerance." | 3.71 | The long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance. ( Deusch, E; Kress, HG; Maier, P; Sator-Katzenschlager, S; Spacek, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banki, L | 1 |
| Büki, A | 1 |
| Horvath, G | 1 |
| Kekesi, G | 1 |
| Kis, G | 1 |
| Somogyvári, F | 1 |
| Jancsó, G | 1 |
| Vécsei, L | 1 |
| Varga, E | 1 |
| Tuboly, G | 1 |
| Shetty, YC | 1 |
| Patil, AE | 1 |
| Jalgaonkar, SV | 1 |
| Rege, NN | 1 |
| Salgaonkar, S | 1 |
| Teltumbde, PA | 1 |
| Kshirsagar, S | 1 |
| Koli, PG | 1 |
| Brahma, S | 1 |
| Lu, W | 1 |
| Wang, L | 1 |
| Wo, C | 1 |
| Yao, J | 1 |
| Sator-Katzenschlager, S | 1 |
| Deusch, E | 1 |
| Maier, P | 1 |
| Spacek, A | 1 |
| Kress, HG | 1 |
4 other studies available for ketamine and Osteoarthritis
| Article | Year |
|---|---|
Distinct changes in chronic pain sensitivity and oxytocin receptor expression in a new rat model (Wisket) of schizophrenia.
Topics: Analgesics, Opioid; Animals; Ankle Joint; Brain; Brain Stem; Chronic Pain; Diencephalon; Disease Mod | 2020 |
Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis.
Topics: Animals; Arthritis, Experimental; Behavior, Animal; Drug Therapy, Combination; Glucose; Hyaluronic A | 2017 |
Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent As | 2016 |
The long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Back Pain; Drug Tolerance; Female; Humans | 2001 |